2021
Multisystem Inflammatory Syndrome in Children — Initial Therapy and Outcomes
Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG. Multisystem Inflammatory Syndrome in Children — Initial Therapy and Outcomes. New England Journal Of Medicine 2021, 385: 23-34. PMID: 34133855, PMCID: PMC8220972, DOI: 10.1056/nejmoa2102605.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolCohort StudiesCombined Modality TherapyCOVID-19COVID-19 Drug TreatmentDrug Therapy, CombinationFemaleGlucocorticoidsHospitalizationHumansImmunoglobulins, IntravenousImmunomodulationInfantLogistic ModelsMalePropensity ScorePublic Health SurveillanceShockSystemic Inflammatory Response SyndromeTreatment OutcomeVentricular Dysfunction, LeftYoung AdultConceptsIntravenous immune globulinMultisystem inflammatory syndromeCardiovascular dysfunctionDay 2Immunomodulatory therapyInflammatory syndromePrimary outcomeInitial treatmentLower riskRisk of feverReal-world effectivenessYears of agePropensity-score matchingImmunomodulatory medicationsVasopressor useVentricular dysfunctionAdjunctive therapyComposite outcomeImmune globulinSecondary outcomesAdjunctive treatmentRecurrent feverInverse probability weightingDay 1GlucocorticoidsIncidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2
Payne AB, Gilani Z, Godfred-Cato S, Belay ED, Feldstein LR, Patel MM, Randolph AG, Newhams M, Thomas D, Magleby R, Hsu K, Burns M, Dufort E, Maxted A, Pietrowski M, Longenberger A, Bidol S, Henderson J, Sosa L, Edmundson A, Tobin-D’Angelo M, Edison L, Heidemann S, Singh AR, Giuliano JS, Kleinman LC, Tarquinio KM, Walsh RF, Fitzgerald JC, Clouser KN, Gertz SJ, Carroll RW, Carroll CL, Hoots BE, Reed C, Dahlgren FS, Oster ME, Pierce TJ, Curns AT, Langley GE, Campbell AP, Balachandran N, Murray T, Burkholder C, Brancard T, Lifshitz J, Leach D, Charpie I, Tice C, Coffin S, Perella D, Jones K, Marohn K, Yager P, Fernandes N, Flori H, Koncicki M, Walker K, Di Pentima M, Li S, Horwitz S, Gaur S, Coffey D, Harwayne-Gidansky I, Hymes S, Thomas N, Ackerman K, Cholette J. Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2. JAMA Network Open 2021, 4: e2116420. PMID: 34110391, PMCID: PMC8193431, DOI: 10.1001/jamanetworkopen.2021.16420.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionMultisystem inflammatory syndromeRace/ethnicityInflammatory syndromeCohort studyPacific Islander personsAge groupsCurrent SARS-CoV-2 infectionIncidence of MISPopulation-based incidenceWhite personsPopulation-based estimatesEnhanced surveillance dataSARS-CoV-2Rare complicationCOVID-19 casesLatino personsNational surveillanceMAIN OUTCOMEInfectionDisease controlIncidenceSurveillance dataCOVID-19Further studies
2018
End-Tidal Carbon Dioxide Use for Tracheal Intubation
Langhan ML, Emerson BL, Nett S, Pinto M, Harwayne-Gidansky I, Rehder KJ, Krawiec C, Meyer K, Giuliano JS, Owen EB, Tarquinio KM, Sanders RC, Shepherd M, Bysani GK, Shenoi AN, Napolitano N, Gangadharan S, Parsons SJ, Simon DW, Nadkarni VM, Nishisaki A. End-Tidal Carbon Dioxide Use for Tracheal Intubation. Pediatric Critical Care Medicine 2018, 19: 98-105. PMID: 29140968, DOI: 10.1097/pcc.0000000000001372.Peer-Reviewed Original ResearchConceptsCapnography useTracheal intubationCardiac arrestEmergency departmentEsophageal intubationOxygen desaturationWaveform capnographyAdverse tracheal intubation-associated eventsMulticenter retrospective cohort studyNational Emergency Airway RegistryTracheal intubation-associated eventsEnd-tidal carbon dioxide measurementPrimary tracheal intubationsRetrospective cohort studyUse of capnographyTracheal intubation procedureQuality improvement initiativesAirway RegistryCohort studyProvider characteristicsSafety outcomesIntubationIntubation procedureCapnographyImprovement initiatives