2024
Interleukin-7-based identification of liver lymphatic endothelial cells reveals their unique structural features
Yang Y, Jeong J, Su T, Lai S, Zhang P, Garcia-Milian R, Graham M, Liu X, McConnell M, Utsumi T, Pereira J, Iwakiri Y. Interleukin-7-based identification of liver lymphatic endothelial cells reveals their unique structural features. JHEP Reports 2024, 6: 101069. PMID: 38966234, PMCID: PMC11222939, DOI: 10.1016/j.jhepr.2024.101069.Peer-Reviewed Original ResearchCell surface structuresLymphatic endothelial cellsPublished single-cell RNA-sequencingRNA-seq analysisScRNA-seq analysisSingle-cell RNA sequencingLymphatic systemEndothelial cellsInterleukin-7RNA-seqScRNA-seqExpressed genesRNA sequencingTranscriptomic changesLow abundanceI/R liver injuryGenesIsolation protocolLiver cell typesCell typesIsolation methodLiver of miceHuman liver specimensHeterozygous miceMouse liver
2018
Cell circuits between B cell progenitors and IL-7+ mesenchymal progenitor cells control B cell development
Fistonich C, Zehentmeier S, Bednarski JJ, Miao R, Schjerven H, Sleckman BP, Pereira JP. Cell circuits between B cell progenitors and IL-7+ mesenchymal progenitor cells control B cell development. Journal Of Experimental Medicine 2018, 215: 2586-2599. PMID: 30158115, PMCID: PMC6170173, DOI: 10.1084/jem.20180778.Peer-Reviewed Original ResearchConceptsB cell progenitorsCell progenitorsUnrepaired double-strand DNA breaksDouble-strand DNA breaksB cell developmentMesenchymal progenitor cellsInterleukin-7IL-7R signalingFocal adhesion kinase expressionBone marrow stromal cellsCell movementMarrow stromal cellsDNA breaksPreB cellsCell developmentParacrine signalsCell behaviorAcute lymphoblastic leukemic cellsProgenitor cellsKinase expressionProgenitorsIL-7RCell exposureStromal cellsLow-adhesion state
2017
Chapter Two A Chemoattractant-Guided Walk Through Lymphopoiesis From Hematopoietic Stem Cells to Mature B Lymphocytes
Lim VY, Zehentmeier S, Fistonich C, Pereira JP. Chapter Two A Chemoattractant-Guided Walk Through Lymphopoiesis From Hematopoietic Stem Cells to Mature B Lymphocytes. Advances In Immunology 2017, 134: 47-88. PMID: 28413023, PMCID: PMC5784265, DOI: 10.1016/bs.ai.2017.02.001.Peer-Reviewed Original ResearchConceptsHematopoietic stem cellsBone marrow parenchymaProgenitor cellsCell motility machinerySpecialized bone marrow nichesMarrow parenchymaStem cellsMultipotent progenitor cellsCommon lymphoid progenitor cellsStem/progenitor cellsBone marrow nicheBone marrow sinusoidsMotility machineryMature B cell poolStem cell factorLymphoid progenitor cellsEndothelial cellsMature B lymphocytesBCR signalingInterleukin-7Multilineage differentiationMarrow nicheHematopoietic cellsCell factorMarrow sinusoids