2017
Chapter Two A Chemoattractant-Guided Walk Through Lymphopoiesis From Hematopoietic Stem Cells to Mature B Lymphocytes
Lim VY, Zehentmeier S, Fistonich C, Pereira JP. Chapter Two A Chemoattractant-Guided Walk Through Lymphopoiesis From Hematopoietic Stem Cells to Mature B Lymphocytes. Advances In Immunology 2017, 134: 47-88. PMID: 28413023, PMCID: PMC5784265, DOI: 10.1016/bs.ai.2017.02.001.Peer-Reviewed Original ResearchConceptsHematopoietic stem cellsBone marrow parenchymaProgenitor cellsCell motility machinerySpecialized bone marrow nichesMarrow parenchymaStem cellsMultipotent progenitor cellsCommon lymphoid progenitor cellsStem/progenitor cellsBone marrow nicheBone marrow sinusoidsMotility machineryMature B cell poolStem cell factorLymphoid progenitor cellsEndothelial cellsMature B lymphocytesBCR signalingInterleukin-7Multilineage differentiationMarrow nicheHematopoietic cellsCell factorMarrow sinusoids
2014
CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow
Beck TC, Gomes AC, Cyster JG, Pereira JP. CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow. Journal Of Experimental Medicine 2014, 211: 2567-2581. PMID: 25403444, PMCID: PMC4267240, DOI: 10.1084/jem.20140457.Peer-Reviewed Original ResearchConceptsGαi protein-coupled receptorsBone marrowCell egressImmature-B cell egressB cell egressTwo-photon intravital microscopyB cell retentionImmature B cellsBM parenchymaProtein-coupled receptorsNK cellsB lineage cellsImmature BLymphoid organsVCAM-1Pertussis toxinB cellsSinusoidal endotheliumIntravital microscopyCXCR4Lineage cellsHematopoietic cellsMarrowCellsMotility