2024
Neuromarkers in addiction: definitions, development strategies, and recent advances
Harp N, Wager T, Kober H. Neuromarkers in addiction: definitions, development strategies, and recent advances. Journal Of Neural Transmission 2024, 131: 509-523. PMID: 38630190, DOI: 10.1007/s00702-024-02766-2.Peer-Reviewed Original ResearchConceptsSubstance use disordersFeatures of substance use disordersResponse to treatmentNeurobiological basisAddiction neuroscienceIndividual treatment outcomesPsychiatric conditionsDetecting response to treatmentPsychological phenomenaNeuromarkersIndex riskSeverity of pathologyTreatment outcomesAbnormal processingAddictionPutative markerClinical practiceStable indicatorSevere pathologyAssess riskNeurosciencePathologyReview recent advancesDisordersTreatment
2021
The self in context: brain systems linking mental and physical health
Koban L, Gianaros PJ, Kober H, Wager TD. The self in context: brain systems linking mental and physical health. Nature Reviews Neuroscience 2021, 22: 309-322. PMID: 33790441, PMCID: PMC8447265, DOI: 10.1038/s41583-021-00446-8.Peer-Reviewed Original ResearchConceptsVentromedial prefrontal cortexDefault mode networkPhysical healthPrefrontal cortexHigh-level cognitionCause of experienceBrain systemsSomatic physiologySensory modalitiesNeural systemsPersonal meaningPeripheral physiologyMental healthFormation of narrativesConvergent alterationsSelfContext modelCortexImmune functionCognitionExperienceContextHealthBeliefsMindset
2020
Computational Models of Drug Use and Addiction: A Review
Mollick JA, Kober H. Computational Models of Drug Use and Addiction: A Review. Journal Of Psychopathology And Clinical Science 2020, 129: 544-555. PMID: 32757599, PMCID: PMC7416739, DOI: 10.1037/abn0000503.Peer-Reviewed Original ResearchConceptsBrain-based modelsBehavioral controlComputational modelGoal-directed systemAspects of addictionCurrent computational modelsExecutive control circuitPredictive coding approachSymptoms of addictionModel of learningComputational accountPrediction errorComputational theoryPrefrontal cortexDrug useBrain areasDorsal striatumAddictionDopamine systemEffects of drugsBasal gangliaHuman dataCoding approachesBroad categoriesMotivation
2019
Let it be: mindful acceptance down-regulates pain and negative emotion
Kober H, Buhle J, Weber J, Ochsner KN, Wager TD. Let it be: mindful acceptance down-regulates pain and negative emotion. Social Cognitive And Affective Neuroscience 2019, 14: 1147-1158. PMID: 31989171, PMCID: PMC7057281, DOI: 10.1093/scan/nsz104.Peer-Reviewed Original ResearchConceptsMindful acceptanceEmotion regulation strategiesCognitive control systemPrefrontal control systemsMeditation-naïve participantsSelf-report measuresKinds of stimuliEmotion regulationNeutral imagesNegative emotionsAmygdala responseMindfulness trainingNegative affectAffective significanceEmotional intensityRegulation strategiesBrain processesNegative imageInitial appraisalEmotionsLateral pain systemPain systemStimuliParticipantsChronic pain
2016
Neural stress reactivity relates to smoking outcomes and differentiates between mindfulness and cognitive-behavioral treatments
Kober H, Brewer JA, Height KL, Sinha R. Neural stress reactivity relates to smoking outcomes and differentiates between mindfulness and cognitive-behavioral treatments. NeuroImage 2016, 151: 4-13. PMID: 27693614, PMCID: PMC5373945, DOI: 10.1016/j.neuroimage.2016.09.042.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentFunctional magnetic resonance imagingStress reactivityMindfulness-based treatmentsAmerican Lung Association's FreedomUnderstanding of stressPsychological mechanismsMindfulness trainingNegative affectConjunction analysisMid insulaCBT groupStress provocationSmoking outcomesBrain regionsCessation treatmentEfficacy of MTCurrent studyEntire sampleDrug useSmoking cessationImportant implicationsMagnetic resonance imagingMindfulnessInsula
2013
Cognitive Reappraisal of Emotion: A Meta-Analysis of Human Neuroimaging Studies
Buhle JT, Silvers JA, Wager TD, Lopez R, Onyemekwu C, Kober H, Weber J, Ochsner KN. Cognitive Reappraisal of Emotion: A Meta-Analysis of Human Neuroimaging Studies. Cerebral Cortex 2013, 24: 2981-2990. PMID: 23765157, PMCID: PMC4193464, DOI: 10.1093/cercor/bht154.Peer-Reviewed Original ResearchConceptsLateral temporal cortexCognitive reappraisalEmotional respondingTemporal cortexSemantic representationEmotion regulation strategiesCognitive control regionsParietal control regionsVentromedial prefrontal cortexHuman neuroimaging studiesEmotion-related responsesCognitive controlEmotional stimuliFear extinctionAmygdala responseNegative affectRegulation strategiesNeuroimaging studiesBilateral amygdalaPrefrontal cortexAffective impactBrain regionsAttenuate activityAmygdalaReappraisal
2012
The brain basis of emotion: A meta-analytic review
Lindquist KA, Wager TD, Kober H, Bliss-Moreau E, Barrett LF. The brain basis of emotion: A meta-analytic review. Behavioral And Brain Sciences 2012, 35: 121-143. PMID: 22617651, PMCID: PMC4329228, DOI: 10.1017/s0140525x11000446.Peer-Reviewed Original ResearchConceptsDiscrete emotion categoriesBrain basisEmotion categoriesBrain regionsMeta-analytic findingsMeta-analytic reviewDistinct brain regionsConstructionist approachMeta-analytic summaryEmotion experienceAffective neurosciencePsychological scienceNeuroimaging literatureHuman emotionsPsychological operationsTarget articleEmotionsSurge of studiesNeurosciencePerceptionLittle evidenceHypothesisMindCategoriesExperience