2022
A neuromarker for drug and food craving distinguishes drug users from non-users
Koban L, Wager T, Kober H. A neuromarker for drug and food craving distinguishes drug users from non-users. Nature Neuroscience 2022, 26: 316-325. PMID: 36536243, DOI: 10.1038/s41593-022-01228-w.Peer-Reviewed Original ResearchConceptsFood cravingsFunctional magnetic resonance imaging studySelf-regulation strategiesCue-induced drugMagnetic resonance imaging studySelf-reported intensityResonance imaging studyFood cuesVentromedial prefrontalSubstance use disordersIntrospective accessMaladaptive behaviorsNeurobiological markersNeurobiological mechanismsParietal association areasCingulate cortexVentral striatumConvergent validityCore featuresCravingAssociation areasSubstance useNeuromarkersUse disordersClinical interventionsBrief training in regulation of craving reduces cigarette smoking
Lopez RB, Ochsner KN, Kober H. Brief training in regulation of craving reduces cigarette smoking. Journal Of Substance Use And Addiction Treatment 2022, 138: 108749. PMID: 35216868, DOI: 10.1016/j.jsat.2022.108749.Peer-Reviewed Original ResearchConceptsRegulation of cravingCognitive behavioral therapySmoking behaviorCognitive regulationLikelihood of relapseCognitive strategiesCue exposureRegulation strategiesTraining conditionsBrief trainingSubsequent smoking behaviorParticipants' smokingTraining procedureSmoking cessationCravingDSM-5Training groupNegative consequencesDaily diariesTraining sessionsCigarette smokingParticipantsDaily lifeAverage cigarettesDiagnostic criteria
2020
Regulating food craving: From mechanisms to interventions
Sun W, Kober H. Regulating food craving: From mechanisms to interventions. Physiology & Behavior 2020, 222: 112878. PMID: 32298667, PMCID: PMC7321886, DOI: 10.1016/j.physbeh.2020.112878.Peer-Reviewed Original ResearchConceptsCognitive strategiesCue reactivityNeural mechanismsCue-induced cravingUnderlying neural mechanismsToxic food environmentSubsequent food choiceFood cravingsCommon experienceCravingFood choicesStrong desireWeight outcomesFuture directionsCausal effectClinical perspectiveImportant lineInterventionTaskFood environmentCaloric consumptionPromising effectsObesity epidemicIndividualsExperience
2018
Training in cognitive strategies reduces eating and improves food choice
Boswell RG, Sun W, Suzuki S, Kober H. Training in cognitive strategies reduces eating and improves food choice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2018, 115: e11238-e11247. PMID: 30420496, PMCID: PMC6275472, DOI: 10.1073/pnas.1717092115.Peer-Reviewed Original ResearchConceptsCognitive strategiesFood valuationBrief trainingUnhealthy foodsCognitive regulation strategiesFood choicesEffects of framingRegulation strategiesStudy 5Study 1Study 3Unhealthy eatingStudy 6Training componentHealthy food choicesNegative consequencesPositive benefitsCravingHealthy foodsTrainingClinical implicationsPrior workIndividualsImplicationsEating
2015
Food cue reactivity and craving predict eating and weight gain: a meta‐analytic review
Boswell RG, Kober H. Food cue reactivity and craving predict eating and weight gain: a meta‐analytic review. Obesity Reviews 2015, 17: 159-177. PMID: 26644270, PMCID: PMC6042864, DOI: 10.1111/obr.12354.Peer-Reviewed Original ResearchConceptsFood cue reactivityCue-induced cravingCue reactivityWeight gainEffect sizeBody mass indexWeight-related outcomesSubsequent weight gainVisual food cuesMass indexTonic cravingFood exposureOverall medium effectClinical implicationsSimilar effect sizesCue exposureMedium effect sizeDietary restraintMeta-analytic reviewFood-related outcomesFood cuesStrong effect sizesCravingSignificant differencesPresent findingsBoundary Conditions of Methamphetamine Craving
Lopez RB, Onyemekwu C, Hart CL, Ochsner KN, Kober H. Boundary Conditions of Methamphetamine Craving. Experimental And Clinical Psychopharmacology 2015, 23: 436-444. PMID: 26302338, PMCID: PMC4658228, DOI: 10.1037/pha0000049.Peer-Reviewed Original ResearchConceptsCognitive strategiesStudy 1Study 2Cognitive regulation strategiesMethamphetamine useNegative consequencesSmoking stimuliRegulation strategiesStrong cravingsMethamphetamine cravingCravingIntranasal stimuliMethamphetamine smokingPositive aspectsMethamphetamine usersMethamphetamine smokersParticipantsSignificant interactionStimuliClinical implicationsExploratory studyRoute of administrationMethamphetamineSmoking methamphetamineAbstinenceNeural Mechanisms Underlying Craving and the Regulation of Craving
Kober H, Mell M. Neural Mechanisms Underlying Craving and the Regulation of Craving. 2015, 195-218. DOI: 10.1002/9781118472415.ch9.ChaptersFunctional magnetic resonance imagingVentral striatumNeural activityRegulation of cravingVentrolateral prefrontal cortexCue-induced cravingMindfulness-based treatmentsAnterior cingulate cortexCentral causal roleWealth of researchCognitive strategiesRegulation strategiesPrefrontal cortexCingulate cortexBrain regionsCravingPositron emission tomography studyCausal roleEmission tomography studiesDrug useAddictionCortexMagnetic resonance imagingResonance imagingAmygdala
2011
Mindful attention reduces neural and self-reported cue-induced craving in smokers
Westbrook C, Creswell JD, Tabibnia G, Julson E, Kober H, Tindle HA. Mindful attention reduces neural and self-reported cue-induced craving in smokers. Social Cognitive And Affective Neuroscience 2011, 8: 73-84. PMID: 22114078, PMCID: PMC3541484, DOI: 10.1093/scan/nsr076.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingMindful attentionCue-induced cravingSmoking cuesSmoking imagesPresent-moment experienceTreatment-seeking smokersPsychophysiological interaction analysisMindfulness-based interventionsSubgenual anterior cingulate cortexAnterior cingulate cortexNeural reactivityNeutral imagesBody of researchMoment experienceNeural markersAddictive disordersCingulate cortexFunctional connectivityNeural activityCuesMindfulnessCravingSmoking cessationAttention