Featured Publications
CORR Insights®: Imposter Syndrome Among Surgeons is Associated With Intolerance of Uncertainty and Lower Confidence in Problem Solving
Friedlaender GE. CORR Insights®: Imposter Syndrome Among Surgeons is Associated With Intolerance of Uncertainty and Lower Confidence in Problem Solving. Clinical Orthopaedics And Related Research® 2022, 481: 672-674. PMID: 36166271, PMCID: PMC10013620, DOI: 10.1097/corr.0000000000002427.Peer-Reviewed Original ResearchReply to the Letter to the Editor: Art in Science: Quackery and Promises Not Kept
Friedlaender GE, Friedlaender LK. Reply to the Letter to the Editor: Art in Science: Quackery and Promises Not Kept. Clinical Orthopaedics And Related Research® 2022, 480: 2060-2060. PMID: 36001023, PMCID: PMC9473757, DOI: 10.1097/corr.0000000000002350.Peer-Reviewed Original ResearchHumansQuackeryArt in Science: Quackery and Promises Not Kept
Friedlaender GE, Friedlaender LK. Art in Science: Quackery and Promises Not Kept. Clinical Orthopaedics And Related Research® 2022, 480: 1458-1460. PMID: 35767816, PMCID: PMC9278922, DOI: 10.1097/corr.0000000000002290.Peer-Reviewed Original ResearchHumansQuackeryArt in Science: Alchemy As Seen Through The Eyes of David Teniers the Younger
Friedlaender GE, Friedlaender LK. Art in Science: Alchemy As Seen Through The Eyes of David Teniers the Younger. Clinical Orthopaedics And Related Research® 2021, 480: 235-236. PMID: 34870955, PMCID: PMC8747614, DOI: 10.1097/corr.0000000000002069.Peer-Reviewed Original ResearchArt in Science: The Boxer at Rest
Chan SM, Moran J, Friedlaender LK, Friedlaender GE. Art in Science: The Boxer at Rest. Clinical Orthopaedics And Related Research® 2021, 479: 1441-1443. PMID: 34106904, PMCID: PMC8208444, DOI: 10.1097/corr.0000000000001847.Peer-Reviewed Original ResearchArt in Science-Humility: As Portrayed by Pietro Lorenzetti.
Flores M, Friedlaender LK, Friedlaender GE. Art in Science-Humility: As Portrayed by Pietro Lorenzetti. Clinical Orthopaedics And Related Research® 2021, 479: 458-460. PMID: 33543878, PMCID: PMC7899731, DOI: 10.1097/corr.0000000000001666.Peer-Reviewed Original ResearchArt in Science-Goya to Dr. Arrieta: An Illustration of Patient-Physician Trust.
Chan SM, Friedlaender GE, Friedlaender LK. Art in Science-Goya to Dr. Arrieta: An Illustration of Patient-Physician Trust. Clinical Orthopaedics And Related Research® 2020, 478: 2221-2224. PMID: 32898044, PMCID: PMC7491894, DOI: 10.1097/corr.0000000000001470.Peer-Reviewed Original ResearchArt in Science: Pieter Bruegel the Elder and the Plague.
Friedlaender GE, Friedlaender LK. Art in Science: Pieter Bruegel the Elder and the Plague. Clinical Orthopaedics And Related Research® 2020, 478: 1416-1418. PMID: 32574469, PMCID: PMC7310395, DOI: 10.1097/corr.0000000000001325.Peer-Reviewed Original Research
2023
Comparison of Percutaneous Interventional Ablation-Osteoplasty-Reinforcement-Internal Fixation (AORIF), Long Intramedullary Nailing, and Hemiarthroplasty for the Treatment of Focal Metastatic Osteolytic Lesions in the Femoral Head and Neck
Jiang W, Friedlaender G, Lindskog D, Latich I, Lee F. Comparison of Percutaneous Interventional Ablation-Osteoplasty-Reinforcement-Internal Fixation (AORIF), Long Intramedullary Nailing, and Hemiarthroplasty for the Treatment of Focal Metastatic Osteolytic Lesions in the Femoral Head and Neck. CardioVascular And Interventional Radiology 2023, 46: 649-657. PMID: 37052716, DOI: 10.1007/s00270-023-03425-x.Peer-Reviewed Original ResearchConceptsOsteolytic lesionsFemoral headSurgical complicationsRevision proceduresLong intramedullary nailingResultsSixty-seven patientsPost-operative complicationsEffective alternative treatmentTraditional surgical approachesAmbulatory scoreCombined painPrimary outcomeMedical complicationsMetastatic lesionsOncologic careRetrospective studyIntramedullary nailingSurgical approachFunction scoresNeck lesionsEarly improvementIM groupHemiarthroplastyComparative efficacyAlternative treatmentPercutaneous Ablation, Osteoplasty, Reinforcement, and Internal Fixation for Pain and Ambulatory Function in Periacetabular Osteolytic Malignancies.
Dussik C, Toombs C, Alder K, Yu K, Berson E, Ibe I, Li F, Lindskog D, Friedlaender G, Latich I, Lee F. Percutaneous Ablation, Osteoplasty, Reinforcement, and Internal Fixation for Pain and Ambulatory Function in Periacetabular Osteolytic Malignancies. Radiology 2023, 307: e221401. PMID: 36916888, DOI: 10.1148/radiol.221401.Peer-Reviewed Original ResearchConceptsOsteolytic neoplasmAmbulatory functionInternal fixationEastern Cooperative Oncology Group scoreIndex scoreConversion hip arthroplastyRetrospective observational studySurgical site infectionKaplan-Meier analysisLong-term painQuality of lifeLong-term improvementWilcoxon signed-rank testNonambulatory patientsSecondary outcomesPrimary outcomeSite infectionOncologic careECOG scorePercutaneous ablationPeriacetabular metastasisProtrusio acetabuliFunctional improvementSigned-rank testClinical data
2020
Bone Scans Have Little Utility in the Evaluation of Well-Differentiated Cartilaginous Lesions of the Humerus.
Samuel AM, Munger AM, Lee FY, Friedlaender GE, Ibe IK, Lindskog DM. Bone Scans Have Little Utility in the Evaluation of Well-Differentiated Cartilaginous Lesions of the Humerus. Orthopedics 2020, 43: e498-e502. PMID: 32882054, DOI: 10.3928/01477447-20200827-05.Peer-Reviewed Original ResearchConceptsRadionuclide bone scanBone scanMRI scansPositive findingsNegative findingsMagnetic resonance imaging (MRI) scansBone scan findingsProgression of lesionsResonance imaging scansDiagnosis of enchondromaAcademic medical centerBivariate logistic regressionAssociation of boneScan findingsAggressive featuresRadiographic findingsEndosteal scallopingBenign enchondromaImaging scansMedical recordsMedical CenterMalignant lesionsCartilaginous lesionsEnchondromaPatientsMinimally Invasive Image-Guided Ablation, Osteoplasty, Reinforcement, and Internal Fixation (AORIF) for Osteolytic Lesions in the Pelvis and Periarticular Regions of Weight-Bearing Bones
Lee FY, Latich I, Toombs C, Mungur A, Conway D, Alder K, Ibe I, Lindskog D, Friedlaender G. Minimally Invasive Image-Guided Ablation, Osteoplasty, Reinforcement, and Internal Fixation (AORIF) for Osteolytic Lesions in the Pelvis and Periarticular Regions of Weight-Bearing Bones. Journal Of Vascular And Interventional Radiology 2020, 31: 649-658.e1. PMID: 32139256, DOI: 10.1016/j.jvir.2019.11.029.Peer-Reviewed Original ResearchMeSH KeywordsAblation TechniquesAdultAgedAged, 80 and overBone CementsBone NeoplasmsBone RemodelingBone ScrewsCalcaneusCementoplastyFemaleFemoral NeoplasmsFemurFracture Fixation, InternalHumansMaleMiddle AgedOsteolysisPelvic BonesPostoperative ComplicationsProspective StudiesRecovery of FunctionTibiaTime FactorsTreatment OutcomeWeight-BearingConceptsOsteolytic lesionsInternal fixationVisual analog scale pain scoreMusculoskeletal Tumor Society scoreProspective clinical cohort studyFunctional ambulation scoreOsteolytic skeletal lesionsPainful osteolytic lesionsScale pain scoresClinical cohort studyInvasive percutaneous approachWeight-bearing boneInternal fixation screwsBalloon osteoplastyPain scoresCohort studyProphylactic stabilizationSevere painSociety ScoreConsecutive patientsSurgical treatmentEarly outcomesTreatment optionsPercutaneous approachFunctional improvement
2016
Case of a Missed Giant Cell Tumor of Bone: An Opportunity to Observe its Natural History Disease.
Russo GS, Rubio DR, Yacob A, Lindskog DM, Alomari AK, Friedlaender GE. Case of a Missed Giant Cell Tumor of Bone: An Opportunity to Observe its Natural History Disease. Connecticut Medicine 2016, 80: 399-403. PMID: 29782126.Peer-Reviewed Case Reports and Technical NotesConceptsGiant cell tumorAnterior cruciate ligamentCell tumorsIncidental findingRoutine preoperative imagingPre-operative MRIInitial MRIPreoperative imagingSecond MRIMetaphyseal lesionsCruciate ligamentEnlarged massBenign neoplasmsRetrospective evaluationNatural historyTumorsYoung womenHistory diseaseMRIBoneLesionsPainPatientsNeoplasmsHistologySaints Cosmas and Damian: Patron Saints of Medicine
Friedlaender GE, Friedlaender LK. Saints Cosmas and Damian: Patron Saints of Medicine. Clinical Orthopaedics And Related Research® 2016, 474: 1765-1769. PMID: 27283584, PMCID: PMC4925431, DOI: 10.1007/s11999-016-4929-6.Peer-Reviewed Original Research
2013
Art in Science: Enhancing Observational Skills
Friedlaender GE, Friedlaender LK. Art in Science: Enhancing Observational Skills. Clinical Orthopaedics And Related Research® 2013, 471: 2065-2067. PMID: 23609813, PMCID: PMC3676632, DOI: 10.1007/s11999-013-3000-0.Peer-Reviewed Original ResearchThe role of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic bone repair and regeneration.
Friedlaender GE, Lin S, Solchaga LA, Snel LB, Lynch SE. The role of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic bone repair and regeneration. Current Pharmaceutical Design 2013, 19: 3384-90. PMID: 23432673, DOI: 10.2174/1381612811319190005.Peer-Reviewed Original ResearchConceptsRecombinant human platelet-derived growth factor-BBClinical studiesMesenchymal stem cellsRecombinant human PDGFStrong mitogenic factorHuman platelet-derived growth factor-BBPlatelet-derived growth factor-BBPivotal clinical studiesImproved safety profileTissue repairGrowth factor-BBMechanism of actionDiabetic patientsChronic footSafety profileAnkle fusionPeriodontal diseaseChronic infectionClinical developmentSoft tissue repairAlveolar boneBone autograftHuman PDGFMitogenic factorFactor-BB
2009
The Need for Increased Access to the U.S. Health-Care System
Bible JE, Lee RS, Friedlaender GE. The Need for Increased Access to the U.S. Health-Care System. Journal Of Bone And Joint Surgery 2009, 91: 476-484. PMID: 19181995, DOI: 10.2106/jbjs.h.00735.Peer-Reviewed Original Research
2007
Measuring the Attitudes and Impact of the Eighty-Hour Workweek Rules on Orthopaedic Surgery Residents
Kusuma S, Mehta S, Sirkin M, Yates A, Miclau T, Templeton K, Friedlaender G. Measuring the Attitudes and Impact of the Eighty-Hour Workweek Rules on Orthopaedic Surgery Residents. Journal Of Bone And Joint Surgery 2007, 89: 679-685. PMID: 17332119, DOI: 10.2106/jbjs.f.00526.Peer-Reviewed Original Research
2006
The 80-hour Duty Week
Friedlaender GE. The 80-hour Duty Week. Clinical Orthopaedics And Related Research® 2006, 449: 138-142. PMID: 16760807, DOI: 10.1097/01.blo.0000224038.31474.30.Peer-Reviewed Original ResearchConceptsMotor vehicle accidentsOperative casesOrthopaedic surgeonsPatient careVehicle accidentsAmerican AcademyGreater riskResidency training programsPoor healthLoss of continuityOrthopaedic residentsGraduate Medical EducationMedical errorsAccreditation CouncilWeeksCareHousestaffSerious consequencesTraining programHoursInjuryHouse dutiesSurgeonsResidents
2003
Malignant bone tumors: limb sparing versus amputation.
DiCaprio MR, Friedlaender GE. Malignant bone tumors: limb sparing versus amputation. Journal Of The American Academy Of Orthopaedic Surgeons 2003, 11: 25-37. PMID: 12699369, DOI: 10.5435/00124635-200301000-00005.Peer-Reviewed Original ResearchConceptsLimb-sparing proceduresAppropriate surgical alternativesFunctional outcome studiesMainstay of treatmentExtent of diseaseAllograft-prosthetic compositeMalignant bone tumorsImportant outcome measureEffective chemotherapeutic agentLimb sparingMost patientsPatient ageReconstructed limbExpandable prosthesisSurgical alternativeTumor locationBone tumorsReconstructive surgeryOutcome measuresOutcome studiesSatisfactory functionModular endoprosthesesSurvival rateBone graftChemotherapeutic agents