2022
Spinal cord protection in open and endovascular approaches to thoracoabdominal aortic aneurysms
Amabile A, Lewis E, Costa V, Tadros RO, Han DK, Di Luozzo G. Spinal cord protection in open and endovascular approaches to thoracoabdominal aortic aneurysms. Vascular 2022, 31: 874-883. PMID: 35507464, DOI: 10.1177/17085381221094411.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCord injuryAortic aneurysmSpinal cordDistal aortic perfusionSubclavian artery revascularizationSpinal cord protectionThoracoabdominal aortic aneurysmsCerebrospinal fluid drainageThoracic aortic aneurysmArtery revascularizationAortic repairEndovascular repairAortic perfusionAortic proceduresEndovascular approachSystemic hypothermiaPostoperative managementExtracorporeal circulationLocal edemaPersistent complicationsFluid drainageCurrent evidenceInjuryAdjunct
2012
Imaging of vascular remodeling after simulated thoracoabdominal aneurysm repair
Geisbüsch S, Schray D, Bischoff MS, Lin HM, Griepp RB, Di Luozzo G. Imaging of vascular remodeling after simulated thoracoabdominal aneurysm repair. Journal Of Thoracic And Cardiovascular Surgery 2012, 144: 1471-1478. PMID: 23010582, PMCID: PMC3496032, DOI: 10.1016/j.jtcvs.2012.08.062.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicArteriesBarium SulfateBehavior, AnimalCollateral CirculationContrast MediaDilatation, PathologicDisease Models, AnimalFemaleLatexLigationMammary ArteriesMultidetector Computed TomographyNeovascularization, PhysiologicParaplegiaReplica TechniquesSpinal CordSpinal Cord IschemiaSwineTime FactorsVascular Surgical ProceduresConceptsAnterior spinal arterySpinal cord blood supplySmall collateral vesselsAneurysm repairCollateral vesselsBlood supplyJuvenile Yorkshire pigsRisk of paraplegiaThoracoabdominal aneurysm repairThoracoabdominal aortic aneurysmsSpinal cord circulationEndovascular repairSpinal arteryArtery sacrificeIntercostal arteriesCord circulationInternal thoracicAortic aneurysmTomographic scanTomographic scanningVascular remodelingGroup 2Group 1Group 3Previous interventions
2011
Staged Approach Prevents Spinal Cord Injury in Hybrid Surgical-Endovascular Thoracoabdominal Aortic Aneurysm Repair: An Experimental Model
Bischoff MS, Scheumann J, Brenner RM, Ladage D, Bodian CA, Kleinman G, Ellozy SH, Di Luozzo G, Etz CD, Griepp RB. Staged Approach Prevents Spinal Cord Injury in Hybrid Surgical-Endovascular Thoracoabdominal Aortic Aneurysm Repair: An Experimental Model. The Annals Of Thoracic Surgery 2011, 92: 138-146. PMID: 21718839, DOI: 10.1016/j.athoracsur.2011.03.098.Peer-Reviewed Original ResearchMeSH KeywordsAngiographyAngioplastyAnimalsAortic Aneurysm, ThoracicCombined Modality TherapyDisease Models, AnimalFemaleFollow-Up StudiesIntraoperative ComplicationsMonitoring, IntraoperativeRandom AllocationRisk AssessmentSpinal CordSpinal Cord InjuriesStentsSurvival RateSwineTreatment OutcomeVascular Surgical ProceduresConceptsGroup 1Group 2Thoracoabdominal aortic aneurysm repairJuvenile Yorkshire pigsSevere ischemic damageHind limb functionAortic aneurysm repairStent graft occlusionLumbar spinal cordModified Tarlov scoreSpinal cord injuryEndovascular coverageTarlov scoreGraft occlusionAneurysm repairArtery ligationIntercostal arteriesIschemic damageCord injuryLimb functionSudden occlusionSpinal cordLower thoracicHistopathologic analysisPorcine modelSpinal Cord Preservation in Thoracoabdominal Aneurysm Repair
Bischoff MS, Di Luozzo G, Griepp EB, Griepp RB. Spinal Cord Preservation in Thoracoabdominal Aneurysm Repair. Perspectives In Vascular Surgery And Endovascular Therapy 2011, 23: 214-222. PMID: 21502113, DOI: 10.1177/1531003511400622.Peer-Reviewed Original ResearchConceptsSpinal cord injuryThoracoabdominal aneurysm repairAneurysm repairIncidence of paraplegiaSpinal cord preservationSpinal cord protectionEndovascular aortic repairOpen surgical repairSpinal cord vasculatureAortic repairEndovascular approachSurgical repairDreadful complicationCord injuryEndovascular proceduresCollateral networkInvasive natureRepairRecent technical advancementsParaparesisComplicationsParaplegiaInjuryIncidenceVasculature
2010
Measuring the collateral network pressure to minimize paraplegia risk in thoracoabdominal aneurysm resection
Etz CD, Zoli S, Bischoff MS, Bodian C, Di Luozzo G, Griepp RB. Measuring the collateral network pressure to minimize paraplegia risk in thoracoabdominal aneurysm resection. Journal Of Thoracic And Cardiovascular Surgery 2010, 140: s125-s130. PMID: 21092778, DOI: 10.1016/j.jtcvs.2010.07.040.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicBlood PressureBlood Pressure DeterminationCatheterization, PeripheralCentral Venous PressureCerebrospinal Fluid PressureCollateral CirculationDisease Models, AnimalHumansParaplegiaRisk AssessmentRisk FactorsSpinal CordSwineTime FactorsVascular Surgical ProceduresConceptsMean aortic pressureSpinal cord injurySegmental arteriesCord injuryAortic pressureSpinal cord perfusion pressureThoracoabdominal aortic aneurysm repairThoracoabdominal aneurysm resectionSpinal cord perfusionAortic aneurysm repairAneurysm resectionParaplegia riskDistal bypassCord perfusionHypogastric arteryAneurysm repairPerfusion pressureArterial ligationEpidural spaceCollateral networkParavertebral musclesPulsatile perfusionArteryOutflow pressureInjuryExperimental Two-Stage Simulated Repair of Extensive Thoracoabdominal Aneurysms Reduces Paraplegia Risk
Zoli S, Etz CD, Roder F, Brenner RM, Bodian CA, Kleinman G, Di Luozzo G, Griepp RB. Experimental Two-Stage Simulated Repair of Extensive Thoracoabdominal Aneurysms Reduces Paraplegia Risk. The Annals Of Thoracic Surgery 2010, 90: 722-729. PMID: 20732484, DOI: 10.1016/j.athoracsur.2010.04.047.Peer-Reviewed Original ResearchConceptsSpinal cord perfusion pressureHind limb functionGroup 2Artery sacrificeLimb functionExtensive segmental artery sacrificeExtensive thoracoabdominal aneurysmsJuvenile Yorkshire pigsSevere ischemic damageMotor-evoked potentialsLumbar spinal cordSpinal cord functionModified Tarlov scoreSpinal cord injuryParaplegia riskTarlov scoreThoracoabdominal aneurysmsAneurysm repairCord functionDistal stumpIschemic damagePerfusion pressureCord injurySpinal cordLower thoracic
2009
Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair
Etz CD, Di Luozzo G, Zoli S, Lazala R, Plestis KA, Bodian CA, Griepp RB. Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair. The Annals Of Thoracic Surgery 2009, 87: 1764-1774. PMID: 19463592, DOI: 10.1016/j.athoracsur.2009.02.101.Peer-Reviewed Original ResearchConceptsSpinal cord perfusion pressureDeep hypothermic circulatory arrestThoracoabdominal aortic aneurysmsAortic aneurysm repairHypothermic circulatory arrestNonpulsatile cardiopulmonary bypassCardiopulmonary bypassPerfusion pressureSegmental arteriesEndovascular repairAneurysm repairCirculatory arrestAortic aneurysmThoracoabdominal aortic aneurysm repairNormal spinal cord functionPerfusion pressure monitoringThoracic segmental arteriesMean arterial pressureSpinal cord functionSpinal cord recoveryParaspinal collateral networkArterial pressureCord functionCollateral networkPressure monitoring