Featured Publications
Standardized measurement of coronary inflammation using cardiovascular computed tomography: integration in clinical care as a prognostic medical device
Oikonomou EK, Antonopoulos AS, Schottlander D, Marwan M, Mathers C, Tomlins P, Siddique M, Klüner LV, Shirodaria C, Mavrogiannis MC, Thomas S, Fava A, Deanfield J, Channon KM, Neubauer S, Desai MY, Achenbach S, Antoniades C. Standardized measurement of coronary inflammation using cardiovascular computed tomography: integration in clinical care as a prognostic medical device. Cardiovascular Research 2021, 117: 2677-2690. PMID: 34450625, DOI: 10.1093/cvr/cvab286.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueAdiposityAdolescentAdultAgedAged, 80 and overAlgorithmsCloud ComputingComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseCoronary VesselsDecision Support TechniquesEnglandFemaleGermanyHeart Disease Risk FactorsHumansInflammationMaleMiddle AgedNomogramsOhioPredictive Value of TestsPrognosisRisk AssessmentTime FactorsYoung AdultConceptsFat attenuation indexPerivascular fat attenuation indexRisk factor-based modelCoronary artery inflammationClinical risk factorsFatal cardiac eventsCoronary artery diseaseCoronary inflammationRisk factorsFAI scorePlaque metricsCardiac eventsArtery inflammationAbsolute riskCoronary arteryClinical careNon-invasive detectionTraditional cardiovascular risk factorsPatient's absolute riskCardiovascular risk factorsFat compositionNet clinical benefitCardiovascular risk predictionDecision curve analysisFirst-line modality
2024
Young and Older Patients with Acute Myocardial Infarction: Differences in Risk Factors and Angiographic Characteristics
Sagris M, Theofilis P, Mistakidou V, Oikonomou E, Tsioufis K, Tousoulis D. Young and Older Patients with Acute Myocardial Infarction: Differences in Risk Factors and Angiographic Characteristics. Hellenic Journal Of Cardiology 2024 PMID: 38734305, DOI: 10.1016/j.hjc.2024.05.008.Peer-Reviewed Original ResearchPulse wave velocityFlow-mediated dilationSingle-vessel diseaseAngiographic characteristicsMyocardial infarctionAugmentation indexOlder patientsCompared to older patientsRisk factorsMI patientsRates of diabetes mellitusPatient baseline characteristicsYoung MI patientsLower pulse wave velocityBiomarkers of inflammationAge groupsCentral augmentation indexCoronary artery diseaseBlood test resultsRisk factor profileIncidence of myocardial infarctionAcute myocardial infarctionYoung adultsMedian ageYounger age groups
2023
Acute Coronary Syndromes in Women: A Narrative Review of Sex-Specific Characteristics.
Theofilis P, Vlachakis P, Mantzouranis E, Sakalidis A, Chrysohoou C, Leontsinis I, Lazaros G, Dimitriadis K, Drakopoulou M, Vordoni A, Oikonomou E, Tsioufis K, Tousoulis D. Acute Coronary Syndromes in Women: A Narrative Review of Sex-Specific Characteristics. Angiology 2023, 33197231218331. PMID: 37995282, DOI: 10.1177/00033197231218331.Peer-Reviewed Original ResearchAcute coronary syndromeCoronary syndromeUnstable anginaSex-specific characteristicsManagement of ACSLife-threatening cardiovascular conditionSex-based differencesClinical presentationFemale patientsMyocardial infarctionClinical managementDiagnostic challengeRisk factorsTreatment strategiesCardiovascular conditionsCardiovascular careNarrative reviewMale populationClinical researchWomenSyndromePivotal roleReview articleSignificant knowledge gapsGreater awarenessThe effect of anthracycline-based chemotherapy on endothelial function and arterial stiffness in breast cancer patients
Anastasiou M, Oikonomou E, Theofilis P, Papamikroulis G, Gazouli M, Pesiridis T, Goliopoulou A, Papatheodoridi D, Psyrri A, Zagouri F, Siasos G, Tousoulis D. The effect of anthracycline-based chemotherapy on endothelial function and arterial stiffness in breast cancer patients. European Heart Journal 2023, 44: ehad655.2675. DOI: 10.1093/eurheartj/ehad655.2675.Peer-Reviewed Original ResearchFlow-mediated dilatationPulse wave velocityAnthracycline-based chemotherapyBreast cancer patientsBreast cancerEndothelial functionArterial stiffnessEndothelial dysfunctionCancer patientsHuman epidermal growth factor receptor-2 (HER2) positive early breast cancerPositive early breast cancerSignificant cardiovascular risk factorsCardiovascular risk factorsInitiation of chemotherapyAddition of trastuzumabEarly breast cancerCase-control studyTrastuzumab treatmentRisk factorsChemotherapyControl groupConsiderable impairmentPatientsCancerTrastuzumabAssociation of fatty liver with left ventricular concentric remodeling: Insights from the Corinthia study
Theofilis P, Mystakidi V, Goliopoulou A, Papamikroulis G, Lazaros G, Vogiatzi G, Anastasiou M, Tsalamandris S, Vavuranaki G, Korakas E, Lambadiari V, Siasos G, Oikonomou E, Tousoulis D. Association of fatty liver with left ventricular concentric remodeling: Insights from the Corinthia study. European Heart Journal 2023, 44: ehad655.2415. DOI: 10.1093/eurheartj/ehad655.2415.Peer-Reviewed Original ResearchNon-alcoholic fatty liver diseaseBody surface areaLeft ventricular concentric remodelingNon-steatosis groupVentricular concentric remodelingCardiovascular risk factorsHepatic steatosis indexLV hypertrophyLV massRisk factorsConcentric remodelingLiver diseasePredictors of NAFLDCardiometabolic risk factorsLV mass indexFatty liver diseaseMajority of patientsIndependent predictive valueLeft ventricular remodelingCross-sectional studyAssociation of steatosisLogistic regression analysisCorinthia studyClinical characteristicsSteatosis indexUse of Smart Devices to Track Cardiovascular Health Goals in the United States
Aminorroaya A, Dhingra L, Nargesi A, Oikonomou E, Krumholz H, Khera R. Use of Smart Devices to Track Cardiovascular Health Goals in the United States. JACC Advances 2023, 2: 100544. PMID: 38094515, PMCID: PMC10718569, DOI: 10.1016/j.jacadv.2023.100544.Peer-Reviewed Original ResearchHealth goalsRisk of cardiovascular diseaseCardiovascular risk factorsNationally representative Health Information National Trends SurveyHealth Information National Trends SurveyU.S. adultsCardiovascular diseaseNational Trends SurveyRisk factors of hypertensionDigital health interventionsCardiovascular health goalsHealth-related goalsRisk of CVDFactors of hypertensionU.S. adult populationCardiovascular risk managementHigher educational attainmentLow-income individualsSmart devicesTrends SurveyImprove careHealth interventionsNational estimatesRisk factorsSurvey participants