Featured Publications
Myelin Oligodendrocyte Glycoprotein–Associated Disorders
Longbrake E. Myelin Oligodendrocyte Glycoprotein–Associated Disorders. CONTINUUM Lifelong Learning In Neurology 2022, 28: 1171-1193. PMID: 35938661, PMCID: PMC9523511, DOI: 10.1212/con.0000000000001127.Peer-Reviewed Original ResearchConceptsAcute disseminated encephalomyelitisClinical spectrumCentral nervous system autoimmune diseaseNatural historyFuture therapeutic trialsLarge cohort studyRecent case reportsDistinct clinical phenotypesDisseminated encephalomyelitisGlycoprotein autoantibodiesOptic neuritisCohort studyMost patientsRelapse patternsNeuromyelitis opticaTherapeutic trialsMultiple sclerosisAutoimmune diseasesCNS diseaseCase reportCNS diseasesAccurate diagnosisClinical phenotypeDiseaseDisorders
2023
Anti-CRMP5 optic neuropathy associated with oral squamous cell carcinoma
Nulton C, Longbrake E, Alkawadri R, Alkawadri C. Anti-CRMP5 optic neuropathy associated with oral squamous cell carcinoma. Neuroimmunology Reports 2023, 3: 100170. DOI: 10.1016/j.nerep.2023.100170.Peer-Reviewed Original ResearchSquamous cell carcinomaParaneoplastic optic neuropathyOptic neuropathyCell carcinomaMagnetic resonance imagingVisual lossDifferential diagnosisHigh-dose intravenous corticosteroidsBilateral optic disc edemaSmall cell lung cancerOral squamous cell carcinomaPositron emission tomography scanNegative infectious workupOptic disc edemaCervical lymph nodesCerebrospinal fluid analysisEmission tomography scanPainless visual lossFirst case reportAntibody elevationDisc edemaInfectious workupIntravenous corticosteroidsOptic neuritisParaneoplastic etiology
2016
Quantitative visual tests after poorly recovered optic neuritis due to multiple sclerosis
Longbrake EE, Lancia S, Tutlam N, Trinkaus K, Naismith RT. Quantitative visual tests after poorly recovered optic neuritis due to multiple sclerosis. Multiple Sclerosis And Related Disorders 2016, 10: 198-203. PMID: 27919490, PMCID: PMC5392253, DOI: 10.1016/j.msard.2016.10.009.Peer-Reviewed Original ResearchConceptsRetinal nerve fiber layerOptic neuritisVisual dysfunctionMS patientsContrast chartsVisual fieldVFQ-25 scoresPelli-Robson contrast sensitivity chartNerve fiber layerSevere visual dysfunctionSnellen eye chartLow contrast chartsCross-sectional studyContrast sensitivity testQuality of lifeContrast sensitivity chartLow-contrast testsOptical coherence tomographyMultiple sclerosisVisual acuityElectrophysiologic functionPatientsEye chartPR chartNeuritis