Featured Publications
The Use of Opioids in the Management of Chronic Pain.
Sall J, Sandbrink F, Murphy J, Spevak C, Edens E. The Use of Opioids in the Management of Chronic Pain. Annals Of Internal Medicine 2023, 176: el230225. PMID: 37722120, DOI: 10.7326/l23-0225.Peer-Reviewed Original ResearchThe Use of Opioids in the Management of Chronic Pain: Synopsis of the 2022 Updated U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline.
Sandbrink F, Murphy J, Johansson M, Olson J, Edens E, Clinton-Lont J, Sall J, Spevak C, Sandbrink F, Murphy J, Johansson M, Spevak C, Clinton-Lont J, MD E, Olson J, Brown N, Guinta R, Macedo F, Nazario M, Pangarkar S, Preston S, Prince M, Real D, Riegleman D, Steil E, Institute E, Group L, Consulting S. The Use of Opioids in the Management of Chronic Pain: Synopsis of the 2022 Updated U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline. Annals Of Internal Medicine 2023, 176: 388-397. PMID: 36780654, DOI: 10.7326/m22-2917.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidChronic PainHumansUnited StatesUnited States Department of Veterans AffairsVeteransConceptsClinical practice guidelinesUse of opioidsChronic painOpioid therapyPractice guidelinesGuideline teamVeterans AffairsVA/DOD Clinical Practice GuidelineDefense Clinical Practice GuidelineJoint clinical practice guidelineVA/DoD EvidenceTrustworthy clinical practice guidelinesFull agonist opioidsGuideline development teamsPractice Work GroupUse of buprenorphineBehavioral health conditionsUse of painSystematic evidence reviewMedicine's tenetsPostsurgical painAgonist opioidsOpioid useOpioid educationHigh riskAddiction and Chronic Pain: Training Addiction Psychiatrists
Edens EL, Gafni I, Encandela J. Addiction and Chronic Pain: Training Addiction Psychiatrists. Academic Psychiatry 2015, 40: 489-493. PMID: 26626792, DOI: 10.1007/s40596-015-0412-z.Peer-Reviewed Original Research
2021
Optimizing Interdisciplinary Virtual Pain Care and Buprenorphine Initiation During COVID-19: A Quality Improvement Study
Edmond SN, Currie S, Gehrke A, Falker CG, Sung M, Abelleira A, Edens EL, Becker WC. Optimizing Interdisciplinary Virtual Pain Care and Buprenorphine Initiation During COVID-19: A Quality Improvement Study. Pain Medicine 2021, 23: 1043-1046. PMID: 34940877, PMCID: PMC9383145, DOI: 10.1093/pm/pnab348.Peer-Reviewed Original Research
2020
Switching From High-Dose, Long-Term Opioids to Buprenorphine: A Case Series.
Becker WC, Frank JW, Edens EL. Switching From High-Dose, Long-Term Opioids to Buprenorphine: A Case Series. Annals Of Internal Medicine 2020, 173: 70-71. PMID: 32252072, DOI: 10.7326/l19-0725.Peer-Reviewed Original Research
2018
Multimodal Treatment Options, Including Rotating to Buprenorphine, Within a Multidisciplinary Pain Clinic for Patients on Risky Opioid Regimens: A Quality Improvement Study
Oldfield BJ, Edens EL, Agnoli A, Bone CW, Cervone DJ, Edmond SN, Manhapra A, Sellinger JJ, Becker WC. Multimodal Treatment Options, Including Rotating to Buprenorphine, Within a Multidisciplinary Pain Clinic for Patients on Risky Opioid Regimens: A Quality Improvement Study. Pain Medicine 2018, 19: s38-s45. PMID: 30203007, DOI: 10.1093/pm/pny086.Peer-Reviewed Original ResearchConceptsPrimary care providersIntake appointmentMorphine equivalent daily dosePartial opioid agonist buprenorphineVeterans Health Administration hospitalsPartial agonist therapiesPrescribed opioid dosesRetrospective cohort studyUnsafe useEquivalent daily doseMultidisciplinary pain clinicMultimodal treatment optionsChronic pain managementPrimary care settingQuality improvement studyHealth system levelHealth system improvementOpioid dosesCohort studyPain clinicDaily doseOpioid regimensPain managementMultidisciplinary clinicTreatment options
2017
Ultra–High-Dose Opioids With Low Efficacy and Significant Harm—Time to Make a Change: A Teachable Moment
Guillod P, Edens EL, Becker WC. Ultra–High-Dose Opioids With Low Efficacy and Significant Harm—Time to Make a Change: A Teachable Moment. JAMA Internal Medicine 2017, 177: 17-18. PMID: 27893881, DOI: 10.1001/jamainternmed.2016.7344.Peer-Reviewed Original Research
2016
Management of patients with issues related to opioid safety, efficacy and/or misuse: a case series from an integrated, interdisciplinary clinic
Becker WC, Merlin JS, Manhapra A, Edens EL. Management of patients with issues related to opioid safety, efficacy and/or misuse: a case series from an integrated, interdisciplinary clinic. Addiction Science & Clinical Practice 2016, 11: 3. PMID: 26818474, PMCID: PMC4730605, DOI: 10.1186/s13722-016-0050-0.Peer-Reviewed Original ResearchConceptsChronic painOpioid safetyInterdisciplinary clinicClinical scenariosCo-occurring chronic painMultimodal pain careManagement of patientsOpioid use disorderTreatment of patientsLack of efficacySimilar clinical scenariosComplex clinical scenariosQuality of careHazardous alcohol useSubstance abuse treatmentOpioid treatmentBuprenorphine/Case seriesPain careMultimodal treatmentClinical equipoisePrimary careUse disordersPainPatients