2020
Prospective, randomized, double-blind, placebo-controlled evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia
Paidas MJ, Tita ATN, Macones GA, Saade GA, Ehrenkranz RA, Triche EW, Streisand JB, Lam GK, Magann EF, Lewis DF, Dombrowski MP, Werner EF, Branch DW, Habli MA, Grotegut CA, Silver RM, Longo SA, Amon E, Cleary K, How HY, Novotny SR, Grobman WA, Whiteman VE, Wing DA, Scifres CM, Sibai BM. Prospective, randomized, double-blind, placebo-controlled evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia. American Journal Of Obstetrics And Gynecology 2020, 223: 739.e1-739.e13. PMID: 32780999, DOI: 10.1016/j.ajog.2020.08.004.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAdolescentAdultAntithrombin ProteinsCesarean SectionDelivery, ObstetricDouble-Blind MethodFemaleFetal DistressGestational AgeHumansInfant, Premature, DiseasesInfant, Small for Gestational AgeMiddle AgedNeonatal SepsisPerinatal MortalityPre-EclampsiaPregnancyPregnancy Trimester, SecondPregnancy Trimester, ThirdProspective StudiesRecombinant ProteinsYoung AdultConceptsRecombinant human antithrombinPreterm preeclampsiaExpectant managementMorbidity scoreHuman antithrombinPlacebo-controlled clinical trialPlacebo-controlled evaluationPlacebo-controlled trialMedian gestational ageMaternal complicationsVersus PlaceboFetal outcomesMaternal outcomesPreterm deliveryEndothelial dysfunctionSecondary outcomesSingleton pregnanciesStandard therapyLoading dosePrimary outcomeWeeks' gestationGestational ageContinuous infusionClinical trialsSaline infusion
2019
Development and Validation of a Risk Prediction Model for Cesarean Delivery After Labor Induction
Danilack VA, Hutcheon JA, Triche EW, Dore DD, Muri JH, Phipps MG, Savitz DA. Development and Validation of a Risk Prediction Model for Cesarean Delivery After Labor Induction. Journal Of Women's Health 2019, 29: 656-669. PMID: 31657668, PMCID: PMC8935479, DOI: 10.1089/jwh.2019.7822.Peer-Reviewed Original ResearchConceptsLabor inductionCesarean deliveryHistory of herpesTerm labor inductionInternal validationExcessive fetal growthBetter risk stratificationExternal validation cohortVariables gestational ageRisk prediction modelStart of inductionRisk stratificationTime of inductionDevelopment cohortValidation cohortMaternal ageFetal growthMaternal raceMedical indicationsWoman's riskU.S. hospitalsCharacteristic curveHospitalCohortInduction
2016
Comparing expectant management and spontaneous labor approaches in studying the effect of labor induction on cesarean delivery
Danilack VA, Triche EW, Dore DD, Muri JH, Phipps MG, Savitz DA. Comparing expectant management and spontaneous labor approaches in studying the effect of labor induction on cesarean delivery. Annals Of Epidemiology 2016, 26: 405-411.e1. PMID: 27211604, DOI: 10.1016/j.annepidem.2016.04.009.Peer-Reviewed Original ResearchConceptsCesarean deliveryLabor inductionExpectant managementRisk ratioWeek 34Week 37Comparison groupRisk of CDIntrauterine growth restrictionMother-newborn dyadsSpontaneous laborVaginal deliveryWeeks' gestationWeek 36Maternal ageSpontaneous onsetGrowth restrictionDiabetic disordersWeek 40High riskLower riskClinical practiceWeek 41Member hospitalsGestation
2015
The Rising Burden of Preeclampsia in the United States Impacts Both Maternal and Child Health
Shih T, Peneva D, Xu X, Sutton A, Triche E, Ehrenkranz RA, Paidas M, Stevens W. The Rising Burden of Preeclampsia in the United States Impacts Both Maternal and Child Health. American Journal Of Perinatology 2015, 33: 329-338. PMID: 26479171, DOI: 10.1055/s-0035-1564881.Peer-Reviewed Original ResearchConceptsEarly-onset preeclampsiaNumerous adverse health consequencesHealth consequencesConsiderable perinatal morbidityAdverse health consequencesEstimates of burdenSeverity of outcomePerinatal morbidityPreterm deliveryPreterm birthTerm pregnancyMaternal mortalityUS incidencePreeclampsiaChild healthEffective treatmentEconomic burdenRising BurdenSocial burdenHealth careBurdenMortalityUnited StatesHealthMothersThe effect of labour induction on the risk of caesarean delivery: using propensity scores to control confounding by indication
Danilack V, Dore D, Triche E, Muri J, Phipps M, Savitz D. The effect of labour induction on the risk of caesarean delivery: using propensity scores to control confounding by indication. BJOG An International Journal Of Obstetrics & Gynaecology 2015, 123: 1521-1529. PMID: 26411752, DOI: 10.1111/1471-0528.13682.Peer-Reviewed Original ResearchConceptsWeeks of gestationCaesarean deliveryLabor inductionRisk ratioPropensity scoreElevated riskNational Perinatal Information CenterPrimary caesarean deliveryRisk of caesareanAdministrative hospital discharge dataHospital discharge dataMedical record informationCross-sectional analysisExpectant managementPreterm deliveryLiveborn deliveryPropensity score methodsGestationMember hospitalsPS adjustmentWeeksCovariate adjustmentSubsequent weeksTraditional covariatesRiskGestational weight gain among American Samoan women and its impact on delivery and infant outcomes
Hawley NL, Johnson W, Hart CN, Triche EW, Ah Ching J, Muasau-Howard B, McGarvey ST. Gestational weight gain among American Samoan women and its impact on delivery and infant outcomes. BMC Pregnancy And Childbirth 2015, 15: 10. PMID: 25643752, PMCID: PMC4324802, DOI: 10.1186/s12884-015-0451-1.Peer-Reviewed Original ResearchConceptsGestational weight gainEarly pregnancy weightTrimester weight gainThird trimester weight gainAmerican Samoan womenPregnancy weightWeight gainInfant outcomesSamoan womenSecond trimester weight gainExcess gestational weight gainExcessive gestational weight gainAppropriate gestational weight gainGreater gestational weight gainMedicine GWG guidelinesPrenatal care recordsOverweight/obeseOverweight/obesityExcess weight gainLevels of obesityOutcomes of interestBinary logistic regressionAdverse pregnancyInfant overweightLGA infants
2014
Low-to-moderate prenatal alcohol consumption and the risk of selected birth outcomes: a prospective cohort study
Lundsberg LS, Illuzzi JL, Belanger K, Triche EW, Bracken MB. Low-to-moderate prenatal alcohol consumption and the risk of selected birth outcomes: a prospective cohort study. Annals Of Epidemiology 2014, 25: 46-54.e3. PMID: 25453352, PMCID: PMC4255148, DOI: 10.1016/j.annepidem.2014.10.011.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingConfidence IntervalsConfounding Factors, EpidemiologicConnecticutFemaleFetal Growth RetardationGestational AgeHumansInfant, Low Birth WeightInfant, NewbornLogistic ModelsMassachusettsMaternal-Fetal ExchangeOdds RatioPregnancyPregnancy ComplicationsPregnancy OutcomePremature BirthProspective StudiesRisk FactorsConceptsIntrauterine growth restrictionLow birthweightPreterm deliveryBirth lengthBirth outcomesGrowth restrictionAlcohol exposureOdds ratioLower oddsModerate prenatal alcohol exposureModerate alcohol exposureThird-trimester drinkingProspective cohort studyMultivariable logistic regressionConfidence intervalsPrenatal alcohol consumptionPrenatal alcohol exposurePregnancy drinkingNeonatal outcomesPerinatal outcomesSingleton infantsCohort studyAlcohol drinkingReduced oddsHead circumference
2012
Correction of Systematic Bias in Ultrasound Dating in Studies of Small-for-Gestational-Age Birth: An Example From the Iowa Health in Pregnancy Study
Harland K, Saftlas A, Wallis A, Yankowitz J, Triche E, Zimmerman M. Correction of Systematic Bias in Ultrasound Dating in Studies of Small-for-Gestational-Age Birth: An Example From the Iowa Health in Pregnancy Study. American Journal Of Epidemiology 2012, 176: 443-455. PMID: 22886591, PMCID: PMC3499119, DOI: 10.1093/aje/kws120.Peer-Reviewed Original ResearchConceptsLast menstrual periodUltrasound gestational ageGestational ageSGA birthEarly ultrasoundPreterm deliveryPopulation-based case-control studyFirst trimester vaginal bleedingFirst trimester prenatal careGestational age fetusesGestational-age birthsCase-control studyStandard guidelinesMultivariable linear regressionDifferent study populationsVaginal bleedingGestational durationSGA fetusesSGA subjectsPrenatal careMaternal ageMenstrual periodPregnancy StudyStudy populationUnadjusted models
2010
Association Between Placental Morphology and Childhood Systolic Blood Pressure
Wen X, Triche E, Hogan J, Shenassa E, Buka S. Association Between Placental Morphology and Childhood Systolic Blood Pressure. Hypertension 2010, 57: 48-55. PMID: 21079045, PMCID: PMC3074204, DOI: 10.1161/hypertensionaha.110.162792.Peer-Reviewed Original ResearchConceptsSystolic blood pressureBlood pressureChildhood systolic blood pressureShort-term blood pressureHigher systolic blood pressureLong-term blood pressureLarger placental sizeFull-term singletonsCollaborative Perinatal ProjectDecidual vesselsPlacental inefficiencyPlacental thicknessPregnancy courseVascular resistancePlacental weightPlacental volumePlacental sizeVascular lesionsCord vesselsPlacental morphologyPerinatal ProjectAuscultation methodLesionsAssociationVessels
2009
Preterm delivery and risk of subsequent cardiovascular morbidity and type‐II diabetes in the mother
Lykke J, Paidas M, Damm P, Triche E, Kuczynski E, Langhoff‐Roos J. Preterm delivery and risk of subsequent cardiovascular morbidity and type‐II diabetes in the mother. BJOG An International Journal Of Obstetrics & Gynaecology 2009, 117: 274-281. PMID: 20015308, DOI: 10.1111/j.1471-0528.2009.02448.x.Peer-Reviewed Original ResearchConceptsRisk of thromboembolismType II diabetesPreterm deliveryCardiovascular morbiditySingleton deliveriesRegistry-based retrospective cohort studyCox proportional hazards modelFirst singleton deliveryHypertensive pregnancy disordersMaternal cardiovascular morbiditySecond singleton deliverySpecific cardiovascular eventsSubsequent cardiovascular morbidityRetrospective cohort studyIschemic heart diseaseWeeks of gestationYear of deliveryProportional hazards modelFetal growth deviationsMaternal hypertensionAdjusted riskCardiovascular eventsPlacental abruptionPregnancy complicationsCohort study
2000
Abortion and Its Effect on Risk of Preeclampsia and Transient Hypertension
Eras J, Saftlas A, Triche E, Hsu C, Risch H, Bracken M. Abortion and Its Effect on Risk of Preeclampsia and Transient Hypertension. Epidemiology 2000, 11: 36-43. PMID: 10615841, DOI: 10.1097/00001648-200001000-00009.Peer-Reviewed Original ResearchConceptsRisk of preeclampsiaTransient hypertensionNulliparous womenDecreased riskMore abortionsPregnancy-related risk factorsHistory of abortionHypertensive disordersWeeks' gestationGestational ageSubsequent pregnancyPrenatal careRisk factorsObstetric practicePrior abortionMonths gestationPreeclampsiaHypertensionInduced abortionReproductive historyReferent groupProtective factorsGestationWomenAbortion