2020
Prospective, randomized, double-blind, placebo-controlled evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia
Paidas MJ, Tita ATN, Macones GA, Saade GA, Ehrenkranz RA, Triche EW, Streisand JB, Lam GK, Magann EF, Lewis DF, Dombrowski MP, Werner EF, Branch DW, Habli MA, Grotegut CA, Silver RM, Longo SA, Amon E, Cleary K, How HY, Novotny SR, Grobman WA, Whiteman VE, Wing DA, Scifres CM, Sibai BM. Prospective, randomized, double-blind, placebo-controlled evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia. American Journal Of Obstetrics And Gynecology 2020, 223: 739.e1-739.e13. PMID: 32780999, DOI: 10.1016/j.ajog.2020.08.004.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAdolescentAdultAntithrombin ProteinsCesarean SectionDelivery, ObstetricDouble-Blind MethodFemaleFetal DistressGestational AgeHumansInfant, Premature, DiseasesInfant, Small for Gestational AgeMiddle AgedNeonatal SepsisPerinatal MortalityPre-EclampsiaPregnancyPregnancy Trimester, SecondPregnancy Trimester, ThirdProspective StudiesRecombinant ProteinsYoung AdultConceptsRecombinant human antithrombinPreterm preeclampsiaExpectant managementMorbidity scoreHuman antithrombinPlacebo-controlled clinical trialPlacebo-controlled evaluationPlacebo-controlled trialMedian gestational ageMaternal complicationsVersus PlaceboFetal outcomesMaternal outcomesPreterm deliveryEndothelial dysfunctionSecondary outcomesSingleton pregnanciesStandard therapyLoading dosePrimary outcomeWeeks' gestationGestational ageContinuous infusionClinical trialsSaline infusion
2016
Physical Activity During Pregnancy and Subsequent Risk of Preeclampsia and Gestational Hypertension: A Case Control Study
Spracklen C, Ryckman K, Triche E, Saftlas A. Physical Activity During Pregnancy and Subsequent Risk of Preeclampsia and Gestational Hypertension: A Case Control Study. Maternal And Child Health Journal 2016, 20: 1193-1202. PMID: 26910608, PMCID: PMC5538351, DOI: 10.1007/s10995-016-1919-y.Peer-Reviewed Original ResearchConceptsRisk of preeclampsiaLeisure-time PAGestational hypertensionSedentary activitiesMedical chart reviewCase-control studyGestational hypertensiveObjectivePhysical activityPreeclampsia resultsPregnancy hypertensionPrepregnancy BMINormotensive womenChart reviewHypertension riskPreeclampsia riskSubsequent riskPreeclampsiaEpidemiologic studiesPA exposurePhysical activityMultinomial logistic regressionHypertensionControl studyDisease statusBirth records
2015
Cigarette smoking and emergency care utilization among asthmatic adults in the 2011 Asthma Call-back Survey
Khokhawalla S, Rosenthal S, Pearlman D, Triche E. Cigarette smoking and emergency care utilization among asthmatic adults in the 2011 Asthma Call-back Survey. Journal Of Asthma 2015, 52: 732-739. PMID: 25563058, DOI: 10.3109/02770903.2015.1004337.Peer-Reviewed Original ResearchConceptsAsthma Call-back SurveyUrgent visitsCall-back SurveyAsthmatic adultsFormer smokersEmergency departmentEmergency careCurrent smokersED visitsEmergency care useEmergency care visitsCessation of smokingCross-sectional study designEmergency care utilizationMultivariable logistic regressionPopulation attributable riskPopulation-based estimatesHealth care costsFormer smokingAdult asthmaticsCare visitsCurrent smokingCare utilizationSmoking statusCigarette smoking
2014
Accuracy of Brief Screening Tools for Identifying Postpartum Depression Among Adolescent Mothers
Venkatesh K, Zlotnick C, Triche E, Ware C, Phipps M. Accuracy of Brief Screening Tools for Identifying Postpartum Depression Among Adolescent Mothers. Pediatrics 2014, 133: e45-e53. PMID: 24344102, PMCID: PMC3876181, DOI: 10.1542/peds.2013-1628.Peer-Reviewed Original ResearchConceptsEdinburgh Postnatal Depression ScalePostpartum depressionPsychiatric diagnostic interviewBrief screening toolScreening toolAdolescent mothersOptimal cutoff scoreCutoff scoreDiagnostic InterviewPatient Health Questionnaire-2Primary care pediatric settingPostnatal Depression ScaleMajor depressive disorderPositive depression screenPrimiparous adolescent mothersDepression screening toolsDepressive symptoms subscalePostpartum visitDepression screenMonths postpartumDepressive disorderDepression ScalePediatric settingDiagnostic criteriaSymptom subscales
2013
The Relationship Between Parental Stress and Postpartum Depression Among Adolescent Mothers Enrolled in a Randomized Controlled Prevention Trial
Venkatesh K, Phipps M, Triche E, Zlotnick C. The Relationship Between Parental Stress and Postpartum Depression Among Adolescent Mothers Enrolled in a Randomized Controlled Prevention Trial. Maternal And Child Health Journal 2013, 18: 1532-1539. PMID: 24281848, PMCID: PMC4603360, DOI: 10.1007/s10995-013-1394-7.Peer-Reviewed Original ResearchConceptsAdjusted odds ratioDepression Rating ScalePostpartum depressionPrimiparous adolescent mothersSubthreshold depressionAdolescent mothersMonths postpartumRisk factorsParental stressDSM-IV Childhood DiagnosesSubsequent postpartum depressionChildren's Depression Rating ScaleSignificant risk factorsStructured Clinical InterviewPostpartum visitMedian agePrevention trialsStudy armsParenting Stress IndexOdds ratioStudy visitDepression diagnosisPrior historyDepression severityClinical InterviewThe association between epilepsy and autism symptoms and maladaptive behaviors in children with autism spectrum disorder
Viscidi E, Johnson A, Spence S, Buka S, Morrow E, Triche E. The association between epilepsy and autism symptoms and maladaptive behaviors in children with autism spectrum disorder. Autism 2013, 18: 996-1006. PMID: 24165273, PMCID: PMC4002664, DOI: 10.1177/1362361313508027.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderAutism symptomsMaladaptive behaviorsAutism phenotypeHyperactivity symptomsSpectrum disorderMore autism symptomsCo-occurring intellectual disabilitySimons Simplex CollectionEpilepsy groupLower IQGreater impairmentMore irritabilityIntellectual disabilityIQChildrenImportant clinical implicationsClinical implicationsDisordersSymptomsBehaviorImpairmentIrritabilityImplicationsAssociationCumulative exposure to paternal seminal fluid prior to conception and subsequent risk of preeclampsia
Saftlas A, Rubenstein L, Prater K, Harland K, Field E, Triche E. Cumulative exposure to paternal seminal fluid prior to conception and subsequent risk of preeclampsia. Journal Of Reproductive Immunology 2013, 101: 104-110. PMID: 24011785, DOI: 10.1016/j.jri.2013.07.006.Peer-Reviewed Original ResearchConceptsRisk of preeclampsiaVaginal exposureNulliparous womenImmune maladaptation hypothesisOdds of preeclampsiaMedical chart reviewPercentile of exposureBarrier contraceptive methodsCase-control studyVaginal sexual intercourseAllogeneic fetusChart reviewIowa womenPaternal HLAAntigen exposureImmune toleranceNormotensive controlsPaternal antigensMaternal tolerancePreeclampsia casesPreeclampsia riskSubsequent riskSeminal fluidLive birthsContraceptive useClinical Characteristics of Children with Autism Spectrum Disorder and Co-Occurring Epilepsy
Viscidi E, Triche E, Pescosolido M, McLean R, Joseph R, Spence S, Morrow E. Clinical Characteristics of Children with Autism Spectrum Disorder and Co-Occurring Epilepsy. PLOS ONE 2013, 8: e67797. PMID: 23861807, PMCID: PMC3701630, DOI: 10.1371/journal.pone.0067797.Peer-Reviewed Original ResearchConceptsPrevalence of epilepsyClinical characteristicsDevelopmental regressionOlder ageAverage prevalenceCo-occurring epilepsyAutism spectrum disorderDate of patientsMultivariate logistic regressionLarger patient populationCross-sectional studyPopulation-based samplePatient populationChildren ages 10Independent associationRisk factorsMultivariate regression modelSpectrum disorderEpilepsyAlert cliniciansSample of childrenLarger studyLogistic regressionPrevalenceAge 10Exploring the Role of Antithrombin Replacement for the Treatment of Preeclampsia: A Prospective Randomized Evaluation of the Safety and Efficacy of Recombinant Antithrombin in Very Preterm Preeclampsia (PRESERVE‐1)
Paidas MJ, Sibai BM, Triche EW, Frieling J, Lowry S, Group T. Exploring the Role of Antithrombin Replacement for the Treatment of Preeclampsia: A Prospective Randomized Evaluation of the Safety and Efficacy of Recombinant Antithrombin in Very Preterm Preeclampsia (PRESERVE‐1). American Journal Of Reproductive Immunology 2013, 69: 539-544. PMID: 23444920, DOI: 10.1111/aji.12091.Peer-Reviewed Original ResearchConceptsProspective Randomized EvaluationAntithrombin replacementWeeks' gestationRandomized EvaluationRecombinant antithrombinTreatment of preeclampsiaRecombinant human ATExpectant managementPreterm preeclampsiaPrimary endpointMaternal indicationsGestational ageStudy enrollmentAT therapyPreeclampsia studyPreeclampsiaGestationHuman ATAT replacementPharmacokinetic activityAntithrombinEfficacySafetyLaboratory assaysDelivery
2012
Implementing Provider‐based Sampling for the National Children's Study: Opportunities and Challenges
Belanger K, Buka S, Cherry DC, Dudley DJ, Elliott MR, Hale DE, Hertz‐Picciotto I, Illuzzi JL, Paneth N, Robbins JM, Triche EW, Bracken MB. Implementing Provider‐based Sampling for the National Children's Study: Opportunities and Challenges. Paediatric And Perinatal Epidemiology 2012, 27: 20-26. PMID: 23215706, DOI: 10.1111/ppe.12005.Peer-Reviewed Original ResearchConceptsNational Children's StudyProvider-based samplingChildren's StudyNational cohort studyPrenatal care providersNational probability sampleType of providerProbability sampleCohort studyPrenatal careCare providersChild healthProvider groupsAge 21Risk estimatesPrimary sampling unitsWomenBirthProvidersHealthSampling frameSecondary sampling unitsPregnancyNumber of strategiesUteroFetal growth and later maternal death, cardiovascular disease and diabetes
LYKKE JA, PAIDAS MJ, TRICHE EW, LANGHOFF‐ROOS J. Fetal growth and later maternal death, cardiovascular disease and diabetes. Acta Obstetricia Et Gynecologica Scandinavica 2012, 91: 503-510. PMID: 22372730, DOI: 10.1111/j.1600-0412.2011.01355.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBirth WeightCardiovascular DiseasesCohort StudiesDenmarkDiabetes MellitusFemaleFetal DevelopmentFollow-Up StudiesHealth Status IndicatorsHumansInfant, NewbornMiddle AgedMortality, PrematurePregnancyProportional Hazards ModelsReference StandardsRegistriesRetrospective StudiesRiskYoung AdultConceptsSubsequent maternal deathIschemic heart diseaseFetal growthPonderal indexMaternal deathsStandardized birthweightHeart diseaseCardiovascular diseaseSubsequent mortalityCox proportional hazards modelFirst singleton deliverySmaller risk estimatesSubsequent diabetes mellitusRetrospective cohort studyProportional hazards modelCardiovascular morbidityPregnancy complicationsCohort studySingleton deliveriesDiabetes mellitusGestational ageLow birthweightPrimary exposureSubsequent riskEarly death
2011
Changes in Sexual Risk Behavior Before and After HIV Seroconversion in Southern African Women Enrolled in a HIV Prevention Trial
Venkatesh K, de Bruyn G, Mayer K, Cheng H, Blanchard K, Ramjee G, Chipato T, Triche E, Padian N, van der Straten A. Changes in Sexual Risk Behavior Before and After HIV Seroconversion in Southern African Women Enrolled in a HIV Prevention Trial. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2011, 57: 435-441. PMID: 21546849, DOI: 10.1097/qai.0b013e318220379b.Peer-Reviewed Original ResearchConceptsSexual risk behaviorsHIV seroconversionRisk behaviorsStudy visitSouthern African womenAnal sexSex partnersCondom useConsistent male condom useImproving Reproductive HealthHIV prevention trialsMale sex partnersMale condom useConsistent condom useSexual behaviorEpisodes of sexAfrican womenSecondary preventionHIV infectionHIV testingHIV statusPrevention trialsAfrica trialSeroconversionFemale condom
2010
Speed- and cane-related alterations in gait parameters in individuals with multiple sclerosis
Gianfrancesco M, Triche E, Fawcett J, Labas M, Patterson T, Lo A. Speed- and cane-related alterations in gait parameters in individuals with multiple sclerosis. Gait & Posture 2010, 33: 140-142. PMID: 20952198, DOI: 10.1016/j.gaitpost.2010.09.016.Peer-Reviewed Original ResearchConceptsGait parametersPreferred speedMultiple sclerosisGait impairmentMS populationBilateral coordinationAdditional trialsStance timeMS participantsCane useSwing timeStride lengthDouble supportDaily activitiesStep length ratioSingle supportAssistive devicesParticipantsIndividualsSclerosisMaximal speedImpairmentTrialsDailyDoes Chocolate Intake During Pregnancy Reduce the Risks of Preeclampsia and Gestational Hypertension?
Saftlas AF, Triche EW, Beydoun H, Bracken MB. Does Chocolate Intake During Pregnancy Reduce the Risks of Preeclampsia and Gestational Hypertension? Annals Of Epidemiology 2010, 20: 584-591. PMID: 20609337, PMCID: PMC2901253, DOI: 10.1016/j.annepidem.2010.05.010.Peer-Reviewed Original ResearchConceptsGestational hypertensionRisk of preeclampsiaAdjusted odds ratioChocolate intakeReduced oddsCardiovascular disease risk markersChocolate consumptionAdverse pregnancy outcomesProspective cohort studyDisease risk markersPrenatal care practicesGH womenCohort studyNormotensive pregnanciesPregnancy outcomesBlood pressureWeeks' gestationThird trimesterHospital deliveryProspective studyRisk markersRisk factorsOdds ratioPrenatal recordsProtective effect
2009
Preterm delivery and risk of subsequent cardiovascular morbidity and type‐II diabetes in the mother
Lykke J, Paidas M, Damm P, Triche E, Kuczynski E, Langhoff‐Roos J. Preterm delivery and risk of subsequent cardiovascular morbidity and type‐II diabetes in the mother. BJOG An International Journal Of Obstetrics & Gynaecology 2009, 117: 274-281. PMID: 20015308, DOI: 10.1111/j.1471-0528.2009.02448.x.Peer-Reviewed Original ResearchConceptsRisk of thromboembolismType II diabetesPreterm deliveryCardiovascular morbiditySingleton deliveriesRegistry-based retrospective cohort studyCox proportional hazards modelFirst singleton deliveryHypertensive pregnancy disordersMaternal cardiovascular morbiditySecond singleton deliverySpecific cardiovascular eventsSubsequent cardiovascular morbidityRetrospective cohort studyIschemic heart diseaseWeeks of gestationYear of deliveryProportional hazards modelFetal growth deviationsMaternal hypertensionAdjusted riskCardiovascular eventsPlacental abruptionPregnancy complicationsCohort study
2002
Dust mite, cockroach, cat, and dog allergen concentrations in homes of asthmatic children in the northeastern United States: impact of socioeconomic factors and population density.
Leaderer BP, Belanger K, Triche E, Holford T, Gold DR, Kim Y, Jankun T, Ren P, McSharry Je JE, Platts-Mills TA, Chapman MD, Bracken MB. Dust mite, cockroach, cat, and dog allergen concentrations in homes of asthmatic children in the northeastern United States: impact of socioeconomic factors and population density. Environmental Health Perspectives 2002, 110: 419-425. PMID: 11940461, PMCID: PMC1240806, DOI: 10.1289/ehp.02110419.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAir Pollution, IndoorAllergensAnimalsAsthmaCatsChildChild, PreschoolCockroachesCohort StudiesConnecticutDogsEducational StatusEnvironmental MonitoringEnzyme-Linked Immunosorbent AssayEpidemiological MonitoringEthnicityFemaleHousingHumansMaleMassachusettsMitesPopulation DensityPovertyRisk AssessmentUrban PopulationConceptsExacerbation of asthmaDog allergensDust miteCockroach allergensLower cut pointCut pointsMore allergensLongitudinal birth cohort studyOngoing longitudinal birth cohort studyBirth cohort studyMultiple logistic regressionSocioeconomic factorsAllergic sensitizationCohort studyAsthmatic childrenAllergen burdenIndividual allergensAsthmatic homesHome exposureAllergen concentrationsHigher household incomeAllergensLogistic regressionMain living areaHome concentrations