2024
bSSFP Phase Contrast (PC-SSFP) at 0.55T Applied to Aortic Flow
Xiang J, Ramasawmy R, Seemann F, Peters D, Campbell-Washburn A. bSSFP Phase Contrast (PC-SSFP) at 0.55T Applied to Aortic Flow. Journal Of Cardiovascular Magnetic Resonance 2024, 101098. PMID: 39278416, DOI: 10.1016/j.jocmr.2024.101098.Peer-Reviewed Original ResearchBalanced steady state free precessionPhase contrastGradient momentsBreath-holdFree-breathing protocolFree breathingGradient echoCardiac outputFree precessionStroke volumeAortic flow quantificationAortic flowPhantomSteady state free precessionSpoiled gradient echoFlow imagingMeasured aortic flowFraction measurementsTeHealthy volunteersVelocity measurementsPlanimetry measurementsCardiac MRHealthy subjectsIncreased SNRTricuspid valve flow measurement using a deep learning framework for automated valve‐tracking 2D phase contrast
Lamy J, Gonzales R, Xiang J, Seemann F, Huber S, Steele J, Wieben O, Heiberg E, Peters D. Tricuspid valve flow measurement using a deep learning framework for automated valve‐tracking 2D phase contrast. Magnetic Resonance In Medicine 2024, 92: 1838-1850. PMID: 38817154, PMCID: PMC11341256, DOI: 10.1002/mrm.30163.Peer-Reviewed Original ResearchStroke volumeHealthy subjectsLong-axis cine imagesTricuspid valve planeTricuspid regurgitation velocityDiastolic function evaluationVentricular stroke volumePhase contrastSystolic excursionRegurgitation velocityTricuspid valveTrace regurgitationDiastolic flowCine imagesTricuspidClinical challengeCardiovascular MRValve planeValvular planeAcquisition planeHigh-velocity jetPatientsTraining deep learning networksPlanimetryDeep learning frameworkConstrained alternating minimization for parameter mapping (CAMP)
Elsaid N, Dispenza N, Hu C, Peters D, Constable R, Tagare H, Galiana G. Constrained alternating minimization for parameter mapping (CAMP). Magnetic Resonance Imaging 2024, 110: 176-183. PMID: 38657714, PMCID: PMC11193090, DOI: 10.1016/j.mri.2024.04.029.Peer-Reviewed Original ResearchConceptsAlternating minimizationAccelerated parameter mappingImage qualityReconstructed image qualityEfficient reconstruction algorithmSacrificing model accuracyParameter mapsPhantom studyK-space samplingAcceleration datasetsK-spaceUndersampling artifactsCartesian acquisitionConsecutive imagesReconstruction algorithmIndividual imagesModel cost functionExponential decayEcho timeReconstruction methodCost functionReduce artifactsPhantomScan timeObjective functionClinical physiology: the crucial role of MRI in evaluation of peripheral artery disease
Elsaid N, Peters D, Galiana G, Sinusas A. Clinical physiology: the crucial role of MRI in evaluation of peripheral artery disease. AJP Heart And Circulatory Physiology 2024, 326: h1304-h1323. PMID: 38517227, PMCID: PMC11381027, DOI: 10.1152/ajpheart.00533.2023.Peer-Reviewed Original ResearchPeripheral arterial diseaseMagnetic resonance imagingArtery diseaseClinical applicationEvaluation of peripheral arterial diseaseTranslation to clinical researchPre-clinical modelsMedial vascular calcificationDiagnosis of peripheral arterial diseaseExcellent soft tissue contrastPathophysiology of peripheral arterial diseaseAssessment of peripheral arterial diseaseNoninvasive imaging toolMR imaging technologyMR imaging techniquesSoft tissue contrastMultiplanar imaging capabilityAutonomic dysfunctionMicrovascular dysfunctionRisk stratificationPeripheral neuropathyComprehensive physiological assessmentTreatment outcomesVascular calcificationTherapy planningThe future of CMR: All-in-one vs. real-time CMR (Part 2)
Contijoch F, Rasche V, Seiberlich N, Peters D. The future of CMR: All-in-one vs. real-time CMR (Part 2). Journal Of Cardiovascular Magnetic Resonance 2024, 26: 100998. PMID: 38237901, PMCID: PMC11211235, DOI: 10.1016/j.jocmr.2024.100998.Peer-Reviewed Original ResearchThe future of cardiovascular magnetic resonance: All-in-one vs. real-time (Part 1)
Christodoulou A, Cruz G, Arami A, Weingärtner S, Artico J, Peters D, Seiberlich N. The future of cardiovascular magnetic resonance: All-in-one vs. real-time (Part 1). Journal Of Cardiovascular Magnetic Resonance 2024, 26: 100997. PMID: 38237900, PMCID: PMC11211239, DOI: 10.1016/j.jocmr.2024.100997.Peer-Reviewed Original ResearchKiosk 5R-TA-01 Left Atrial Evaluation in Immune Check Point Inhibitor Myocarditis Using Cardiac Magnetic Resonance Imaging and Correlations with Cardiovascular Outcomes
Jeyashanmugaraja G, Kwan J, Shah N, Lamy J, Khattab M, Chehayeb R, Guajardo A, Lin D, Christofides A, Alkhatib D, Martinez C, Im Y, Salem J, Redheuil A, Peters D, Baldassarre L. Kiosk 5R-TA-01 Left Atrial Evaluation in Immune Check Point Inhibitor Myocarditis Using Cardiac Magnetic Resonance Imaging and Correlations with Cardiovascular Outcomes. Journal Of Cardiovascular Magnetic Resonance 2024, 26: 100677. DOI: 10.1016/j.jocmr.2024.100677.Peer-Reviewed Original ResearchKiosk 9R-TA-01 Automated CMR Index of Left Ventricular Diastolic Function (e’): A Validation Study Against Echocardiography in the Large-scale beta3-lvh Trial
Gonzales R, Arvidsson P, Lukaschuk E, Balligand J, Heiberg E, Peters D, Zhang Q, Ferreira V, Piechnik S. Kiosk 9R-TA-01 Automated CMR Index of Left Ventricular Diastolic Function (e’): A Validation Study Against Echocardiography in the Large-scale beta3-lvh Trial. Journal Of Cardiovascular Magnetic Resonance 2024, 26: 100955. DOI: 10.1016/j.jocmr.2024.100955.Peer-Reviewed Original ResearchKiosk 10R-TB-11 Automated CMR Index of Left Ventricular Diastolic Function Post-acute Myocardial Infarction Provides Independent and Incremental Prediction of Long-term Prognosis When Added to Conventional Indices
Shanmuganathan M, Gonzales R, Burrage M, Arvidsson P, Banerjee A, Cakir I, Seemann F, Heiberg E, Peters D, Zhang Q, Channon K, Piechnik S, Ferreira V. Kiosk 10R-TB-11 Automated CMR Index of Left Ventricular Diastolic Function Post-acute Myocardial Infarction Provides Independent and Incremental Prediction of Long-term Prognosis When Added to Conventional Indices. Journal Of Cardiovascular Magnetic Resonance 2024, 26: 100268. DOI: 10.1016/j.jocmr.2024.100268.Peer-Reviewed Original ResearchKiosk 5R-TB-01 Prospective Evaluation of Immune Checkpoint Inhibitor Myocarditis with Serial Quantitative Cardiovascular Magnetic Resonance and Correlations with Cardiovascular Outcomes
Khattab M, Kwan J, Chehayeb R, Guajardo A, Lin D, Christophides A, Alkhatib D, Martinez C, Shah N, Im Y, Jeyashanmugaraja G, Ragheb E, Higgins A, Redheiul A, Salem J, Peters D, Mohjibian H, Baldassarre L. Kiosk 5R-TB-01 Prospective Evaluation of Immune Checkpoint Inhibitor Myocarditis with Serial Quantitative Cardiovascular Magnetic Resonance and Correlations with Cardiovascular Outcomes. Journal Of Cardiovascular Magnetic Resonance 2024, 26: 100686. DOI: 10.1016/j.jocmr.2024.100686.Peer-Reviewed Original Research
2023
High-sensitivity deuterium metabolic MRI differentiates acute pancreatitis from pancreatic cancers in murine models
Montrazi E, Sasson K, Agemy L, Peters D, Brenner O, Scherz A, Frydman L. High-sensitivity deuterium metabolic MRI differentiates acute pancreatitis from pancreatic cancers in murine models. Scientific Reports 2023, 13: 19998. PMID: 37968574, PMCID: PMC10652017, DOI: 10.1038/s41598-023-47301-7.Peer-Reviewed Original ResearchCover Image, Volume 36, Issue 11
Montrazi E, Bao Q, Martinho R, Peters D, Harris T, Sasson K, Agemy L, Scherz A, Frydman L. Cover Image, Volume 36, Issue 11. NMR In Biomedicine 2023, 36 DOI: 10.1002/nbm.5067.Peer-Reviewed Original ResearchDeuterium imaging of the Warburg effect at sub‐millimolar concentrations by joint processing of the kinetic and spectral dimensions
Montrazi E, Bao Q, Martinho R, Peters D, Harris T, Sasson K, Agemy L, Scherz A, Frydman L. Deuterium imaging of the Warburg effect at sub‐millimolar concentrations by joint processing of the kinetic and spectral dimensions. NMR In Biomedicine 2023, 36: e4995. PMID: 37401393, DOI: 10.1002/nbm.4995.Peer-Reviewed Original ResearchTime-resolved spectroscopic imagingSub-millimolar concentrationsDeuterated substratesLow-concentration metabolitesDeuterium metabolic imagingSignal-to-noise ratioResonance positionsWarburg effectDeuteriumDetection of low-concentration metabolitesPancreatic cancer studiesSteady-state free precessionBalanced steady-state free precessionKineticsDiagnosed cancerMetabolic kineticsSignal-to-noise ratio improvementMetabolic imagingChemical shift imagingImproving SNR in deuterium metabolic imaging of cancer: spatial denoising, joint spectral/metabolic-kinetics processing, and beyond
Montrazi E, Bao Q, Martinho R, Peters D, Harris T, Sasson K, Agemy L, Scherz A, Frydman L. Improving SNR in deuterium metabolic imaging of cancer: spatial denoising, joint spectral/metabolic-kinetics processing, and beyond. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/3869.Peer-Reviewed Original Research2.5D Flow MRI: 2D phase-contrast of the tricuspid valvular flow with automated valve-tracking
Lamy J, Xiang J, Seemann F, Gonzales R, Huber S, Steele J, Heiberg E, Peters D. 2.5D Flow MRI: 2D phase-contrast of the tricuspid valvular flow with automated valve-tracking. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/0930.Peer-Reviewed Original ResearchAssociated with diastolic dysfunctionTricuspid regurgitation velocityRV stroke volumePhase contrastDiastolic dysfunctionTricuspid regurgitationPulmonary hypertensionRegurgitation velocityPressure overloadRight heartHealthy subjectsTricuspidPhase contrast methodStroke volumeFlow MRIRegurgitationValvular flowPatientsPhase-dependent mannerFlow volumeEchocardiographyImproved Deuterium Metabolic Imaging of Cancer by CSI-SSFP MRSI
Montrazi E, Peters D, Sasson K, Agemy L, Scherz A, Frydman L. Improved Deuterium Metabolic Imaging of Cancer by CSI-SSFP MRSI. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/0016.Peer-Reviewed Original ResearchImpaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis
Feher A, Miller E, Peters D, Mojibian H, Sinusas A, Hinchcliff M, Baldassarre L. Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis. Rheumatology International 2023, 43: 849-858. PMID: 36894756, DOI: 10.1007/s00296-023-05294-6.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementLV-GLSSystemic sclerosisWorse survivalClinical indicationsImpaired left ventricular global longitudinal strainLeft ventricular global longitudinal strainPresence of LGECMR strainLV cardiac indexWorse LV-GLSLV ejection fractionCox regression analysisGlobal longitudinal strainLV cardiac outputGlobal radialCardiac indexOverall survivalRetrospective cohortEjection fractionPrognostic valueAdverse outcomesCardiac outputGadolinium enhancementRV strain
2022
Balanced Steady‐State Free Precession Cine MR Imaging in the Presence of Cardiac Devices: Value of Interleaved Radial Linear Combination Acquisition With Partial Dephasing
Xiang J, Lamy J, Lampert R, Peters D. Balanced Steady‐State Free Precession Cine MR Imaging in the Presence of Cardiac Devices: Value of Interleaved Radial Linear Combination Acquisition With Partial Dephasing. Journal Of Magnetic Resonance Imaging 2022, 58: 782-791. PMID: 36373998, PMCID: PMC11238270, DOI: 10.1002/jmri.28528.Peer-Reviewed Original ResearchTVnet: automated global analysis of tricuspid valve plane motion in CMR long-axis cines with residual neural networks for assessment of right ventricular function
Gonzales R, Lamy J, Thomas K, Zhang Q, Shanmuganathan M, Heiberg E, Ferreira V, Piechnik S, Peters D. TVnet: automated global analysis of tricuspid valve plane motion in CMR long-axis cines with residual neural networks for assessment of right ventricular function. European Heart Journal - Cardiovascular Imaging 2022, 23: jeac141.019. DOI: 10.1093/ehjci/jeac141.019.Peer-Reviewed Original ResearchTricuspid annular plane systolic excursionCardiovascular magnetic resonanceRV SRoutine clinical workflowHealth Research Oxford Biomedical Research CentreRight ventricular function evaluationAnnular plane systolic excursionTricuspid valve motionRight ventricular functionVentricular function evaluationCongenital heart diseaseNational InstituteComprehensive cardiac assessmentClinical workflowHigh diagnostic performanceBiomedical Research CentreArrhythmogenic RVPulmonary hypertensionRV functionSystolic excursionVentricular functionBland-Altman plotsRV structureCardiac assessmentMyocardial infarction2H multi-echo bSSFP highlights pancreatic ductal adenocarcinomas and distinguishes them from pancreatitis in murine models
Montrazi E, Bao Q, Peters D, Sasson K, Agemy L, Scherz A, Frydman L. 2H multi-echo bSSFP highlights pancreatic ductal adenocarcinomas and distinguishes them from pancreatitis in murine models. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2022 DOI: 10.58530/2022/1354.Peer-Reviewed Original Research