Effects of Androgens and Estradiol on Spine Synapse Formation in the Prefrontal Cortex of Normal and Testicular Feminization Mutant Male Rats
Hajszan T, MacLusky NJ, Johansen JA, Jordan CL, Leranth C. Effects of Androgens and Estradiol on Spine Synapse Formation in the Prefrontal Cortex of Normal and Testicular Feminization Mutant Male Rats. Endocrinology 2007, 148: 1963-1967. PMID: 17317772, PMCID: PMC2128740, DOI: 10.1210/en.2006-1626.Peer-Reviewed Original ResearchConceptsSpine synapse formationMale ratsWild-type animalsPrefrontal cortexTfm ratsSpine synapsesAndrogen receptorSynapse formationEffects of androgensSynaptogenic actionsTfm malesGonadal steroidsSynaptogenic effectsGonadal hormonesSynaptic remodelingTfm animalsFemale monkeysRatsCortexCortical spinesCognitive effectsAndrogensReceptorsSynapsesAdult males