2005
Exercise and improved insulin sensitivity in older women: evidence of the enduring benefits of higher intensity training
DiPietro L, Dziura J, Yeckel CW, Neufer PD. Exercise and improved insulin sensitivity in older women: evidence of the enduring benefits of higher intensity training. Journal Of Applied Physiology 2005, 100: 142-149. PMID: 16141382, DOI: 10.1152/japplphysiol.00474.2005.Peer-Reviewed Original ResearchConceptsHigh-intensity exercise trainingIntensity exercise trainingExercise trainingAerobic trainingInsulin sensitivityExercise volumeOlder womenGlucose utilizationModerate-intensity aerobic trainingTwo-step euglycemic-hyperinsulinemic clampInsulin-stimulated glucose utilizationHigh-intensity aerobic trainingDual-energy X-ray absorptiometryHigher insulin doseLower insulin doseHealthy older womenEuglycemic hyperinsulinemic clampLow-intensity exerciseTotal body fatAdipose tissue lipolysisImproved glucose utilizationX-ray absorptiometrySuppression of lipolysisFinal exercise boutInsulin-stimulated suppression
2004
Leg glucose and protein metabolism during an acute bout of resistance exercise in humans
Durham WJ, Miller SL, Yeckel CW, Chinkes DL, Tipton KD, Rasmussen BB, Wolfe RR. Leg glucose and protein metabolism during an acute bout of resistance exercise in humans. Journal Of Applied Physiology 2004, 97: 1379-1386. PMID: 15194677, DOI: 10.1152/japplphysiol.00635.2003.Peer-Reviewed Original ResearchConceptsLeg blood flowResistance exercisePhenylalanine rateLeg glucoseAcute boutBlood flowLactate releaseProtein breakdownWhole-body protein breakdownLower body resistance exerciseGlucose uptakeLeg glucose uptakeLeg lactate releaseBody resistance exerciseVenous blood samplesMuscle protein synthesisProtein metabolismBody protein breakdownExercise regimenExercise boutLeg pressGlutamate uptakeMuscle biopsyProtein synthesisBlood samples