2018
False-Positive Light Chain Clonal Restriction by Flow Cytometry in Patients Treated With Alemtuzumab
Chen PP, Tormey CA, Eisenbarth SC, Torres R, Richardson SS, Rinder HM, Smith BR, Siddon AJ. False-Positive Light Chain Clonal Restriction by Flow Cytometry in Patients Treated With Alemtuzumab. American Journal Of Clinical Pathology 2018, 151: 154-163. PMID: 30307483, DOI: 10.1093/ajcp/aqy129.Peer-Reviewed Original ResearchConceptsHealthy donor bloodAlemtuzumab treatmentDonor bloodBone marrowFlow cytometryLight chain restrictionT-cell prolymphocytic leukemiaB-cell neoplasmsLight chain clonalityFlow cytometry analysisAutoimmune diseasesHematologic malignanciesImmunophenotypic analysisChain restrictionAlemtuzumabT cellsB cellsProlymphocytic leukemiaImmunoglobulin G1PatientsMonoclonal antibodiesCytometry analysisSimilar findingsBloodClonal restriction
1989
Flow cytometric surface light chain analysis of lymphocyte‐rich effusions. A useful adjunct to cytologic diagnosis
Ibrahim R, Teich D, Smith B, Antin J, Olivier A, Weinberg D. Flow cytometric surface light chain analysis of lymphocyte‐rich effusions. A useful adjunct to cytologic diagnosis. Cancer 1989, 63: 2024-2029. PMID: 2495164, DOI: 10.1002/1097-0142(19890515)63:10<2024::aid-cncr2820631026>3.0.co;2-h.Peer-Reviewed Original ResearchConceptsLymphocyte-rich effusionsLight chain analysisCytologic diagnosisFalse-positive resultsCytologic studyFalse negative rateCell marker studiesSmall lymphocytic lymphomaBody cavity fluidsClinical outcomesLymphoproliferative disordersLymphocytic lymphomaLymphatic leukemiaCytologic evaluationSmall lymphocytesCytologic analysisBenign effusionsUseful adjunctClinical diagnosisPatientsEffusionLymphomaDiagnosisMarker studiesCavity fluid