2023
Utility of Hook Sign in the Diagnosis of Median Arcuate Ligament Syndrome
Chan S, Weininger G, Kozhimala M, Sumpio B, Levine L, Harris S, Zheng S, Ochoa Chaar C, Guzman R, Sumpio B. Utility of Hook Sign in the Diagnosis of Median Arcuate Ligament Syndrome. Annals Of Vascular Surgery 2023, 94: 165-171. PMID: 37023920, DOI: 10.1016/j.avsg.2023.03.018.Peer-Reviewed Original ResearchConceptsMedian arcuate ligament syndromeBody mass indexCeliac artery compressionArcuate ligament syndromeCeliac arteryInstitutional review board-approved retrospective chart reviewDiagnosis of MALSElectronic medical record reviewMedian arcuate ligamentNonspecific abdominal painRetrospective chart reviewMedical record reviewTertiary academic centerSignificant predictorsHook signWilcoxon rank sum testRank sum testMALS patientsAbdominal painTomography angiography imagesArtery compressionChart reviewPatient demographicsArcuate ligamentRadiologic characteristicsHyperspectral imaging in systemic sclerosis-associated Raynaud phenomenon
Teaw S, Gupta A, Williams A, Wilson F, Sumpio B, Sumpio B, Hinchcliff M. Hyperspectral imaging in systemic sclerosis-associated Raynaud phenomenon. Arthritis Research & Therapy 2023, 25: 10. PMID: 36670487, PMCID: PMC9854186, DOI: 10.1186/s13075-023-02990-3.Peer-Reviewed Original ResearchConceptsRaynaud's condition scoreCochin Hand Function ScaleSSc patientsClinic settingPatient-reported outcome instrumentsResultsNinety-two percentSystemic sclerosis patientsMann-Whitney U testHealthy control participantsCHF scoreSSc durationSSc-RPDigital ulcersCutaneous SScProvocation challengeRaynaud's phenomenonSclerosis patientsClinical trialsOutcome instrumentsOxygen saturationBurden assessmentPatientsCold provocationHemoglobin concentrationDisease severity
2022
Prevalence and Characteristics of Patients with Median Arcuate Ligament Syndrome in a Cohort Diagnosed with Celiac Artery Compression.
Kozhimala M, Chan S, Weininger G, Sumpio B, Levine L, Harris S, Zheng S, Longo W, Ochoa Chaar C, Guzman R, Sumpio B. Prevalence and Characteristics of Patients with Median Arcuate Ligament Syndrome in a Cohort Diagnosed with Celiac Artery Compression. Journal Of The American College Of Surgeons 2022, 236: 1085-1091. PMID: 36476640, DOI: 10.1097/xcs.0000000000000500.Peer-Reviewed Original ResearchConceptsMedian arcuate ligament syndromeCeliac artery compressionArcuate ligament syndromeCharacteristics of patientsMALS patientsArtery compressionArtery diseaseRenal diseaseMesenteric artery diseasePeripheral arterial diseasePeripheral artery diseaseRetrospective chart reviewCohort of patientsMedical record reviewFrequent differential diagnosisSignificant differencesAbdominal symptomsAtherosclerotic characteristicsEpigastric painGastrointestinal comorbiditiesChart reviewArterial diseaseAtherosclerotic diseaseRecord reviewClinical symptoms
2019
Safety and efficacy of venous ablation in octogenarians
Aurshina A, Zhang Y, Zhuo H, Cardella J, Orion K, Sumpio B, Sarac T, Chaar C. Safety and efficacy of venous ablation in octogenarians. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2019, 7: 685-692. PMID: 31421837, DOI: 10.1016/j.jvsv.2019.05.006.Peer-Reviewed Original ResearchConceptsVenous ablationYounger patientsTechnical successClinical successAge groupsRetrospective single-center reviewSingle-center reviewResolution of symptomsNumeric rating scaleAdvanced clinical stageSuperficial venous insufficiencyLarger vein diametersIntensity of symptomsYounger age groupsCardiovascular comorbiditiesPain improvementConsecutive patientsOutpatient officePathophysiology (CEAP) classificationVenous insufficiencyVenous diseaseClinical stageDuplex ultrasoundPatient populationUltrasound findingsA Pilot Study of a Standardized Smoking Cessation Intervention for Patients with Vascular Disease
Rajaee S, Holder T, Indes JE, Muhs B, Sarac T, Sumpio B, Toll BA, Ochoa Chaar CI. A Pilot Study of a Standardized Smoking Cessation Intervention for Patients with Vascular Disease. Annals Of Vascular Surgery 2019, 61: 91-99.e3. PMID: 31449932, DOI: 10.1016/j.avsg.2019.06.017.Peer-Reviewed Original ResearchMeSH KeywordsAneurysmCardiovascular AgentsCholinergic AgentsConnecticutEndovascular ProceduresFemaleHumansMaleMiddle AgedNicotinePatient Education as TopicPeripheral Arterial DiseasePilot ProjectsRisk FactorsRisk Reduction BehaviorSmokersSmokingSmoking CessationTime FactorsTobacco Use Cessation DevicesTransdermal PatchTreatment OutcomeVascular Surgical ProceduresConceptsSmoking cessation interventionIntervention groupSurgery providersPrimary outcomeCessation interventionsExact testBrief smoking cessation counselingCurrent smoking cessation practicesCarbon monoxide breath testingSmoking cessation counselingSmoking cessation practicesVascular surgery serviceSmoking cessation counseling sessionsTertiary care centerFree nicotine patchesSmoking cessation programOpen surgical proceduresOutpatient smoking cessation programFisher's exact testCessation counselingVascular complicationsStandard careNicotine patchNicotine replacementVascular patientsCosts and complications of endovascular inferior vena cava filter retrieval
Brahmandam A, Skrip L, Mojibian H, Aruny J, Sumpio B, Dardik A, Sarac T, Ochoa Chaar CI. Costs and complications of endovascular inferior vena cava filter retrieval. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2019, 7: 653-659.e1. PMID: 31307952, DOI: 10.1016/j.jvsv.2019.02.017.Peer-Reviewed Original ResearchConceptsAdvanced endovascular techniquesIVC filter retrievalFilter dwell timeInferior vena cava filter retrievalEndovascular techniquesFilter retrievalProcedural costsAdditional endovascular techniquesVenous ultrasound examinationVenous access sitesAbnormal radiologic findingsComputed tomography scanTotal procedural timeComplication rateMost complicationsPatient characteristicsTertiary centerRadiologic findingsOutside hospitalIVC filtersLower extremitiesTomography scanUltrasound examinationAccess siteBronchoscopy forcepsHigher Inpatient Mortality for Women after Intervention for Lifestyle Limiting Claudication
Miller SM, Sumpio BJ, Miller MS, Erben Y, Cordova AC, Sumpio BE. Higher Inpatient Mortality for Women after Intervention for Lifestyle Limiting Claudication. Annals Of Vascular Surgery 2019, 58: 54-62. PMID: 30910650, DOI: 10.1016/j.avsg.2019.01.006.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedComorbidityCritical IllnessDatabases, FactualEndovascular ProceduresFemaleHealth Status DisparitiesHospital MortalityHumansIntermittent ClaudicationIschemiaMalePatient AdmissionPeripheral Arterial DiseaseRisk AssessmentRisk FactorsSex FactorsTime FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresConceptsLifestyle-limiting claudicationHigher inpatient mortalityCritical limb ischemiaPeripheral artery diseaseInpatient mortalitySex-related differencesVascular interventionsEV interventionsArtery diseaseChronic obstructive pulmonary diseaseRegression analysisChronic renal failureObstructive pulmonary diseaseOpen surgical repairCoronary artery diseaseNationwide Inpatient SampleLogistic regression analysisChi-squared testLimb ischemiaRenal failureIndependent predictorsOpen repairPulmonary diseaseSurgical repairTreatment guidelinesUse of Closed-Incision Negative-Pressure Therapy: Cardiothoracic and Vascular Surgery.
Wu RT, Sumpio BJ, Miller S, Sumpio BE. Use of Closed-Incision Negative-Pressure Therapy: Cardiothoracic and Vascular Surgery. Plastic & Reconstructive Surgery 2019, 143: 31s-35s. PMID: 30586101, DOI: 10.1097/prs.0000000000005310.Peer-Reviewed Original ResearchConceptsNegative pressure therapyVascular surgeryClosed incision negative pressure therapyIncision negative pressure therapySurgical site infectionMedian sternotomy infectionsGroin woundsSerious sequelaeSite infectionSternotomy infectionsGauze dressingsTraditional gauze dressingsSurgeryTherapyCardiothoracicInfectionRecent enthusiasmComplicationsSequelae
2018
A survey of vascular specialists’ practice patterns of inferior vena cava filter placement and retrieval
Brahmandam A, Skrip L, Sumpio B, Indes J, Dardik A, Sarac T, Rectenwald J, Chaar CIO. A survey of vascular specialists’ practice patterns of inferior vena cava filter placement and retrieval. Vascular 2018, 27: 291-298. PMID: 30501583, DOI: 10.1177/1708538118815394.Peer-Reviewed Original ResearchMeSH KeywordsAttitude of Health PersonnelDevice RemovalHealth Care SurveysHealth Knowledge, Attitudes, PracticeHospitals, High-VolumeHospitals, Low-VolumeHumansPractice Patterns, Physicians'Prosthesis ImplantationRadiologistsRadiology, InterventionalSurgeonsTime FactorsUltrasonography, Doppler, DuplexUnited StatesVena Cava FiltersConceptsInferior vena cava filterVascular specialistsIVCF retrievalPractice patternsBronchoscopy forcepsRetrieval of IVCFTemporary inferior vena cava filterPermanent inferior vena cava filterInferior vena cava filter placementVena cava filter placementRetrievable inferior vena cava filtersLaser sheathLowest renal veinTertiary care centerCava filter placementVena cava filtersMajority of respondersChi-square testTwo-sample t-testVenous duplexRenal veinCare centerFilter placementSocietal guidelinesLower extremitiesRegulation of Yes-Associated Protein by Laminar Flow
Chitragari G, Shalaby SY, Sumpio BJ, Kurita J, Sumpio BE. Regulation of Yes-Associated Protein by Laminar Flow. Annals Of Vascular Surgery 2018, 52: 183-191. PMID: 29758328, DOI: 10.1016/j.avsg.2018.03.002.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingCell ShapeCells, CulturedCytoskeletonDown-RegulationHuman Umbilical Vein Endothelial CellsHumansMechanotransduction, CellularPhosphoproteinsPhosphorylationProteolysisPulsatile FlowRegional Blood FlowStress, MechanicalTime FactorsTranscription FactorsYAP-Signaling ProteinsConceptsHuman umbilical vein endothelial cellsTotal YAPExposure of HUVECsRelease of mediatorsYAP levelsSignificant decreaseUbiquitin-proteasome system inhibitorsUmbilical vein endothelial cellsEndothelial cell proliferationVein endothelial cellsVascular healthSystem inhibitorsYes-Associated ProteinDisease modulationIntimal hyperplasiaDisturbed flowEndothelial cellsBlood vesselsDisease statesPotential targetCell proliferationProteasome-independent mechanismExposureKey regulatorPYAPThe effect of increasing catheter distance from the deep junction on the outcomes of radiofrequency vein ablation
Aurshina A, Zhang Y, Wang F, Cardella J, Orion K, Sumpio B, Sarac T, Chaar C. The effect of increasing catheter distance from the deep junction on the outcomes of radiofrequency vein ablation. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2018, 6: 614-620. PMID: 29784594, DOI: 10.1016/j.jvsv.2018.04.006.Peer-Reviewed Original ResearchConceptsVein ablationGroup BMultivariable analysisTechnical successClinical successRetrospective single-center reviewSingle-center reviewSuperficial venous refluxDeep venous thrombosisGroup A. Group BNumeric rating scalePast medical historyPredictors of recurrenceSaphenous vein ablationDeep venous systemLong-term recurrenceLarger vein diametersIntensity of symptomsCatheter distanceVenous refluxComplication rateVenous thrombosisRecurrence rateMean ageMedical historyRadiotracer Imaging Allows for Noninvasive Detection and Quantification of Abnormalities in Angiosome Foot Perfusion in Diabetic Patients With Critical Limb Ischemia and Nonhealing Wounds
Alvelo JL, Papademetris X, Mena-Hurtado C, Jeon S, Sumpio BE, Sinusas AJ, Stacy MR. Radiotracer Imaging Allows for Noninvasive Detection and Quantification of Abnormalities in Angiosome Foot Perfusion in Diabetic Patients With Critical Limb Ischemia and Nonhealing Wounds. Circulation Cardiovascular Imaging 2018, 11: e006932. PMID: 29748311, PMCID: PMC5951395, DOI: 10.1161/circimaging.117.006932.Peer-Reviewed Original ResearchMeSH KeywordsAnkle Brachial IndexCase-Control StudiesCritical IllnessDiabetic FootHumansIschemiaMicrocirculationOrganophosphorus CompoundsOrganotechnetium CompoundsPerfusion ImagingPredictive Value of TestsRadiopharmaceuticalsRegional Blood FlowSingle Photon Emission Computed Tomography Computed TomographyWound HealingConceptsCritical limb ischemiaAnkle-brachial indexStandardized uptake valueSPECT/CT imagingDiabetic patientsHealthy subjectsSPECT/CTFoot perfusionUptake valueLimb ischemiaMicrovascular perfusionSkeletal muscle microvascular perfusionCT imagingDiabetic CLI patientsMuscle microvascular perfusionPeripheral artery diseaseSingle photon emissionIntraclass correlation coefficientAngiosome perfusionCLI subjectsCLI patientsArtery diseaseDiabetes mellitusCT perfusionVascular territoriesThe effect of commercial insurance policies on outcomes of venous ablation
Chaar C, Aurshina A, Zhang Y, Wang F, Cardella J, Orion K, Sumpio B, Sarac T. The effect of commercial insurance policies on outcomes of venous ablation. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2018, 6: 331-337.e1. PMID: 29661363, DOI: 10.1016/j.jvsv.2017.11.013.Peer-Reviewed Original ResearchConceptsQuality of lifeVenous ablationChronic venous insufficiencyClinical successTechnical successComplication rateMultivariable analysisVenous insufficiencySubgroup analysisImprovement of QOLRetrospective single-center reviewNumeric rating scale scoreSingle-center reviewResolution of symptomsNumeric rating scaleTechnical success rateBlue Cross Blue ShieldImproved patient outcomesRating Scale scoresIntensity of symptomsSignificant differencesC3 diseaseChart reviewIndependent predictorsProcedural successAcute Limb Ischemia in an 8-Year-Old Patient: A Case Report
Erben Y, Miller SM, Sumpio BJ, Dillon BJ, Lee AI, Blume P, Sumpio BE, Mena-Hurtado C. Acute Limb Ischemia in an 8-Year-Old Patient: A Case Report. Annals Of Vascular Surgery 2018, 51: 327.e1-327.e8. PMID: 29655809, DOI: 10.1016/j.avsg.2018.02.012.Peer-Reviewed Original ResearchConceptsAnkle-brachial indexNormal ankle-brachial indexRight foot painAcute limb ischemiaLower extremity angiographyLeg length discrepancyFoot insertsIntermittent painIntravenous heparinFoot painLimb ischemiaOlder patientsNephrotic syndromeEmergency departmentPhysical examinationCapillary refillCase reportLength discrepancyLeft footPatient's motherPatientsPainMothersFootFasciotomyEndovascular interventions decrease length of hospitalization and are cost-effective in acute mesenteric ischemia
Erben Y, Protack CD, Jean RA, Sumpio BJ, Miller SM, Liu S, Trejo G, Sumpio BE. Endovascular interventions decrease length of hospitalization and are cost-effective in acute mesenteric ischemia. Journal Of Vascular Surgery 2018, 68: 459-469. PMID: 29459015, DOI: 10.1016/j.jvs.2017.11.078.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAcute Kidney InjuryAdolescentAdultAgedAged, 80 and overComorbidityCost SavingsCost-Benefit AnalysisDatabases, FactualEndovascular ProceduresFemaleHospital CostsHospital MortalityHumansLength of StayLinear ModelsLogistic ModelsMaleMesenteric IschemiaMesenteric Vascular OcclusionMiddle AgedMultivariate AnalysisOdds RatioPatient DischargePropensity ScoreProportional Hazards ModelsRetrospective StudiesRisk FactorsSplanchnic CirculationTime FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresYoung AdultConceptsAcute mesenteric ischemiaAcute kidney injuryEndovascular interventionHospital mortalityMesenteric ischemiaHospitalization costsOpen groupPropensity-adjusted logistic regression analysisTreatment of AMISevere Charlson Comorbidity IndexEnd pointCharlson Comorbidity IndexOpen surgical revascularizationPrimary end pointSecondary end pointsIncreased hazard ratioLength of hospitalizationMean hospitalization costNational Inpatient SampleCost of hospitalizationLogistic regression analysisSkilled nursing facilitiesLower mortality rateComorbidity indexHospital stayImproved mortality in treatment of patients with endovascular interventions for chronic mesenteric ischemia
Erben Y, Jean RA, Protack CD, Chiu AS, Liu S, Sumpio BJ, Miller SM, Sumpio BE. Improved mortality in treatment of patients with endovascular interventions for chronic mesenteric ischemia. Journal Of Vascular Surgery 2018, 67: 1805-1812. PMID: 29395425, DOI: 10.1016/j.jvs.2017.10.071.Peer-Reviewed Original ResearchConceptsChronic mesenteric ischemiaCost of hospitalizationNational Inpatient SampleMesenteric ischemiaHospital factorsENDO groupCharlson Comorbidity Index scoreEnd pointComorbidity Index scorePrimary end pointSecondary end pointsTreatment of patientsHealth care costsLower mortality rateHospital mortalityHospital stayImproved mortalityLonger LOSMean LOSImproved survivalMean ageEndovascular interventionInpatient SampleOpen groupDevastating diagnosisIncreased mortality in octogenarians treated for lifestyle limiting claudication
Erben Y, Mena‐Hurtado C, Miller S, Jean R, Sumpio BJ, Velasquez CA, Mojibian H, Aruny J, Dardik A, Sumpio B. Increased mortality in octogenarians treated for lifestyle limiting claudication. Catheterization And Cardiovascular Interventions 2018, 91: 1331-1338. PMID: 29405592, DOI: 10.1002/ccd.27523.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overComorbidityDatabases, FactualEndovascular ProceduresFemaleHealth StatusHumansIntermittent ClaudicationLength of StayMaleMiddle AgedPeripheral Arterial DiseaseRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresConceptsCharlson Comorbidity IndexOpen surgeryTreatment modalitiesHigher Charlson comorbidity indexMean Charlson Comorbidity IndexYounger cohortsInfectious wound complicationsInfra-inguinal interventionsAcute kidney injuryPeripheral arterial diseasePeripheral artery diseaseCongestive heart failureNationwide Inpatient SampleBinary logistic regression analysisLogistic regression analysisSkilled nursing facilitiesTreatment of LLCHospital mortalityComorbidity indexExercise therapyHospital stayKidney injuryOverall morbidityWound complicationsLonger LOS
2017
Popliteal Artery Entrapment Syndrome: Bilateral Lower Extremity Involvement.
Henry HT, Szolomayer LK, Sumpio BE, Sutton KM. Popliteal Artery Entrapment Syndrome: Bilateral Lower Extremity Involvement. Orthopedics 2017, 41: e295-e298. PMID: 28934539, DOI: 10.3928/01477447-20170918-10.Peer-Reviewed Original ResearchConceptsPopliteal artery entrapment syndromeArtery entrapment syndromeEntrapment syndromeBilateral popliteal artery entrapment syndromeExertional compartment syndromeLower extremity claudicationSuccessful surgical treatmentFemale collegiate athletesPopliteal neurovascular structuresCompartment syndromeExtremity involvementPersistent disabilitySurgical treatmentUnnecessary morbiditySurgical interventionPhysical examinationThorough historyAthlete's returnIdentification of individualsNeurovascular structuresSyndromeCollegiate athletesAnatomic structuresDiagnosisClaudicationManagement of Chronic Wounds: Diagnosis, Preparation, Treatment, and Follow-up.
Gupta S, Andersen C, Black J, de Leon J, Fife C, Lantis Ii JC, Niezgoda J, Snyder R, Sumpio B, Tettelbach W, Treadwell T, Weir D, Silverman RP. Management of Chronic Wounds: Diagnosis, Preparation, Treatment, and Follow-up. WOUNDS A Compendium Of Clinical Research And Practice 2017, 29: s19-s36. PMID: 28862980.Peer-Reviewed Original ResearchConceptsChronic wound typesChronic woundsWound typesCare settingsAccurate diagnosisCurrent evidence-based guidelinesPressure ulcers/injuriesVenous leg ulcersEvidence-based guidelinesEvidence-based criteriaTerms of prevalenceLeg ulcersPatient adherenceTreatment algorithmDiabetic footTherapy optionsWound recurrenceSurgical woundsCare plansHolistic careTherapy selectionChronic wound diagnosisAppropriate managementDiagnosisExpert panelDistal embolization during lower extremity endovascular interventions
Chaar C, Shebl F, Sumpio B, Dardik A, Indes J, Sarac T. Distal embolization during lower extremity endovascular interventions. Journal Of Vascular Surgery 2017, 66: 143-150. PMID: 28366300, DOI: 10.1016/j.jvs.2017.01.032.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalAngioplasty, BalloonAtherectomyChi-Square DistributionCritical IllnessDatabases, FactualDisease-Free SurvivalEmbolismFemaleFemoral ArteryHumansIncidenceIntermittent ClaudicationIschemiaLimb SalvageLower ExtremityMaleMiddle AgedMultivariate AnalysisNew EnglandOdds RatioPeripheral Arterial DiseaseProportional Hazards ModelsRegistriesRetrospective StudiesRisk AssessmentRisk FactorsStentsTime FactorsTreatment OutcomeVascular PatencyConceptsLower extremity endovascular interventionsSuperficial femoral arteryCritical limb ischemiaDistal embolizationLoss of patencyEndovascular interventionBalloon angioplastyLimb ischemiaAdditional endovascular interventionArterial endovascular interventionUse of atherectomyVascular Study GroupLength of occlusionNew England databaseNumber of arteriesMajor amputationMost patientsPatient characteristicsFemoral arteryRisk factorsStudy groupMultivariable regressionLimb lossLower riskAngioplasty