2024
Placental cytochrome P450 methylomes in infants exposed to prenatal opioids: exploring the effects of neonatal opioid withdrawal syndrome on health horizons
Radhakrishna U, Sadhasivam S, Radhakrishnan R, Forray A, Muvvala S, Metpally R, Patel S, Rawal R, Vishweswaraiah S, Bahado-Singh R, Nath S. Placental cytochrome P450 methylomes in infants exposed to prenatal opioids: exploring the effects of neonatal opioid withdrawal syndrome on health horizons. Frontiers In Genetics 2024, 14: 1292148. PMID: 38264209, PMCID: PMC10805101, DOI: 10.3389/fgene.2023.1292148.Peer-Reviewed Original ResearchNeonatal opioid withdrawal syndromeOpioid withdrawal syndromePlacental tissueWithdrawal syndromeLong-term clinical implicationsPrenatal opioid exposureNOWS treatmentPrenatal opioidsOpioid exposureOpioid effectsOpioid usePharmacologic treatmentCYP genesControl mothersMultiple CYP genesValuable biomarkerClinical implicationsInfantsPersonalized treatmentOpioidsCytochrome P450 enzymesInfinium MethylationEPIC BeadChipTreatmentIllumina Infinium MethylationEPIC BeadChipSyndrome
2015
Substance Use in the Perinatal Period
Forray A, Foster D. Substance Use in the Perinatal Period. Current Psychiatry Reports 2015, 17: 91. PMID: 26386836, PMCID: PMC4671272, DOI: 10.1007/s11920-015-0626-5.Peer-Reviewed Original ResearchConceptsPerinatal substance usePerinatal periodSubstance useMajor public health problemPublic health problemUse of tobaccoFetal outcomesFetal effectsFetal healthCurrent treatmentPsychosocial interventionsPolysubstance useHealth problemsNovel interventionsMost efficacyCocaine useIllicit substancesContingency managementPregnancyInterventionTreatmentOpioidsTobaccoProgesteroneRecent literature