2024
Higher proceduralist stroke thrombectomy volume is associated with reduced inpatient mortality
Koo A, Renedo D, Ney J, Amllay A, Kanzler M, Stogniy S, Alawieh A, Sujijantarat N, Antonios J, Al Kasab S, Malhotra A, Hebert R, Matouk C, de Havenon A. Higher proceduralist stroke thrombectomy volume is associated with reduced inpatient mortality. Journal Of NeuroInterventional Surgery 2024, jnis-2024-022021. PMID: 39214687, DOI: 10.1136/jnis-2024-022021.Peer-Reviewed Original ResearchIn-hospital deathIn-hospital mortalityAcute ischemic strokeCut-pointsAbsolute risk of deathAssociated with lower oddsState Inpatient DatabasesFlorida State Inpatient DatabaseIn-hospital moralityRates of in-hospital mortalityDiagnosis of acute ischemic strokePrimary study outcomeRisk of deathStroke careOptimal cut-pointAssociated with reduced inpatient mortalityEndovascular thrombectomyRetrospective cohort studyLower oddsPotential confoundersAbsolute riskAcute ischemic stroke patientsInpatient mortalityCohort studyInpatient DatabaseImpact of Baseline Collateral Status Assessed on Perfusion Scans on Patient Outcomes in Acute Ischemic Stroke: A Meta-analysis and Systematic Review (P2-5.001)
Nayar D, Bajaj S, Malhotra A. Impact of Baseline Collateral Status Assessed on Perfusion Scans on Patient Outcomes in Acute Ischemic Stroke: A Meta-analysis and Systematic Review (P2-5.001). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206669.Peer-Reviewed Original ResearchClinical Applications of Dual‐Energy Computed Tomography for Acute Ischemic Stroke
Chen H, Bodanapally U, Colasurdo M, Malhotra A, Gandhi D. Clinical Applications of Dual‐Energy Computed Tomography for Acute Ischemic Stroke. Stroke Vascular And Interventional Neurology 2024, 4 DOI: 10.1161/svin.123.001193.Peer-Reviewed Educational MaterialsDual-energy computed tomographyAcute ischemic strokePostinterventional managementIschemic strokeDual-energyClinical applicationPredicting hemorrhagic transformationContext of acute ischemic strokeDiagnostic challengePatient selectionEarly cerebral ischemiaHemorrhagic transformationRecanalization therapyComputed tomographyClinical evidenceDiagnostic accuracyTreatment strategiesAcute stroke triageVascular lesionsNeurological disabilityCerebral ischemiaDiagnostic imagingTomographyStroke triageNarrative reviewTime-driven activity-based costing (TDABC) of direct-to-angiography pathway for acute ischemic stroke patients with suspected large vessel occlusion
Sangha K, White T, Boltyenkov A, Bastani M, Sanmartin M, Katz J, Malhotra A, Rula E, Naidich J, Sanelli P. Time-driven activity-based costing (TDABC) of direct-to-angiography pathway for acute ischemic stroke patients with suspected large vessel occlusion. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 107516. PMID: 38183964, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107516.Peer-Reviewed Original ResearchAcute ischemic strokeEndovascular treatmentAcute ischemic stroke patientsAppropriate patient selection criteriaNovel care pathwayIschemic stroke patientsLarge vessel occlusionPatient selection criteriaInstitutional patient databaseTime-driven activity-based costingEligible patientsAnterior circulationIschemic strokeClinical outcomesPatient factorsStroke patientsAIS patientsVessel occlusionCare pathwayPatient costsMain cost driversPatientsPatient databaseAngiography suiteCT pathway
2022
Associations of Osteoarthritis With Thrombectomy Utilization and Outcomes for Large Vessel Acute Ischemic Stroke
Chen H, Khunte M, Colasurdo M, Jindal G, Malhotra A, Gandhi D, Chaturvedi S. Associations of Osteoarthritis With Thrombectomy Utilization and Outcomes for Large Vessel Acute Ischemic Stroke. Stroke 2022, 54: 518-526. PMID: 36541211, DOI: 10.1161/strokeaha.122.041749.Peer-Reviewed Original ResearchConceptsMultivariable logistic regression modelEndovascular thrombectomyAssociation of osteoarthritisLogistic regression modelsHospital mortalityMedical comorbiditiesIschemic strokeRisk factorsLower oddsLarge vessel acute ischemic strokeNational Inpatient Sample databaseMultivariable logistic regression analysisLarge-vessel ischemic strokeIntravenous thrombolysis treatmentStroke risk factorsAcute ischemic strokeIschemic stroke patientsPresence of osteoarthritisCause of disabilityCross-sectional studyLogistic regression analysisPatient selection practicesLarge-scale cross-sectional studyDirect risk factorEVT treatment
2020
CT Angiography for Triage of Patients with Acute Minor Stroke: A Cost-effectiveness Analysis.
Wu X, Hughes DR, Gandhi D, Matouk CC, Sheth K, Schindler J, Wira C, Wintermark M, Sanelli P, Malhotra A. CT Angiography for Triage of Patients with Acute Minor Stroke: A Cost-effectiveness Analysis. Radiology 2020, 294: 580-588. PMID: 31934828, DOI: 10.1148/radiol.2019191238.Peer-Reviewed Original ResearchConceptsLarge vessel occlusionAcute minor strokeBest medical managementMinor strokeCT angiographyMedical managementProbabilistic sensitivity analysesLower health benefitsImmediate thrombectomyHealth benefitsHealth outcomesVascular imagingAcute ischemic strokeMarkov decision-analytic modelWorse health outcomesImproved health outcomesDecision analytic modelNet monetary benefitIntravenous thrombolysisIschemic strokeYounger patientsThrombectomy strategyPatientsAngiographyStroke
2019
Culprit intracranial plaque without substantial stenosis in acute ischemic stroke on vessel wall MRI: A systematic review
Wang Y, Liu X, Wu X, Degnan AJ, Malhotra A, Zhu C. Culprit intracranial plaque without substantial stenosis in acute ischemic stroke on vessel wall MRI: A systematic review. Atherosclerosis 2019, 287: 112-121. PMID: 31254918, PMCID: PMC6707846, DOI: 10.1016/j.atherosclerosis.2019.06.907.Peer-Reviewed Original ResearchConceptsIschemic stroke patientsVessel wall MRISubstantial stenosisIschemic strokeStroke patientsMagnetic resonance angiographyIntracranial plaquesPlaque featuresAtherosclerotic plaquesSystematic reviewHigh-resolution vessel wall MRIHigh-risk plaque featuresAcute ischemic stroke patientsProgressive motor deficitsAcute ischemic strokeIntracranial atherosclerotic plaquesOverall functional outcomeHigh-risk plaquesRelevant clinical dataArterial atherosclerotic plaquesArticle reference listsAcute strokeCulprit plaquesIntracranial atherosclerosisMotor deficitsComparative Effectiveness of Endovascular Thrombectomy in Elderly Stroke Patients
Malhotra A, Wu X, Payabvash S, Matouk CC, Forman HP, Gandhi D, Sanelli P, Schindler J. Comparative Effectiveness of Endovascular Thrombectomy in Elderly Stroke Patients. Stroke 2019, 50: 963-969. PMID: 30908156, DOI: 10.1161/strokeaha.119.025031.Peer-Reviewed Original ResearchConceptsQuality-adjusted life yearsIntravenous thrombolysisEndovascular thrombectomyLarge vessel occlusionAge 80 yearsEVT strategyVessel occlusionModified Rankin Scale scorePoststroke functional outcomeAcute ischemic strokeRankin Scale scoreElderly stroke patientsMarkov decision-analytic modelYears of ageDecision analytic modelMultiple sensitivity analysesPurpose- StrokeAcute strokeBaseline disabilityElderly patientsIschemic strokeStroke patientsFunctional outcomeHealthy patientsAdvanced ageNeuroimaging of Pediatric Arteriopathies
Goyal P, Malhotra A, Almast J, Sapire J, Gupta S, Mangla M, Mangla R. Neuroimaging of Pediatric Arteriopathies. Journal Of Neuroimaging 2019, 29: 287-308. PMID: 30920080, DOI: 10.1111/jon.12614.Peer-Reviewed Original ResearchConceptsIschemic strokeMajor prognostic implicationsPediatric ischemic strokeSecondary stroke preventionAcute ischemic strokeFocal neurologic deficitsAdult stroke populationSmall vessel arteriopathyNoninflammatory etiologiesRecurrent strokeStroke preventionSystemic complicationsCerebral arteriopathyNeurologic deficitsStroke etiologyAcute managementPrompt diagnosisStroke populationNeuropsychiatric symptomsClinical manifestationsClinical symptomsPrognostic implicationsPredominant vesselRisk factorsSchool-aged children