Nitric oxide stimulates guanylate cyclase and regulates sodium transport in rabbit proximal tubule
Roczniak A, Burns K. Nitric oxide stimulates guanylate cyclase and regulates sodium transport in rabbit proximal tubule. American Journal Of Physiology 1996, 270: f106-f115. PMID: 8769828, DOI: 10.1152/ajprenal.1996.270.1.f106.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiological TransportCarrier ProteinsCells, CulturedCyclic AMP-Dependent Protein KinasesCyclic GMPEnzyme ActivationFemaleGuanylate CyclaseKidney Tubules, ProximalNitric OxideNitroprussidePenicillamineRabbitsS-Nitroso-N-AcetylpenicillamineSodiumSodium-Hydrogen ExchangersSodium-Phosphate Cotransporter ProteinsSymportersConceptsS-nitroso-N-acetylpenicillamineProximal tubule cellsRabbit proximal tubuleSoluble guanylate cyclaseProtein kinase AProximal tubulesSodium nitroprussideNa+/H+ exchangeTubule cellsGuanylate cyclaseNitric oxidePrimary cultures of proximal tubule cellsAmiloride-sensitive 22Na+ uptakeNa+ transportInhibitor of soluble guanylate cyclaseFractional excretion of lithiumRabbit proximal tubule cellsApical Na+/H+ exchangerGuanosine 3',5'-cyclic monophosphateStable end-products of NOEnd-products of NORegulating sodium transportNO stimulates soluble guanylate cyclaseEffects of NO donorsDose-dependent increase