2024
Individuals as active co-creators of their environments: implications for prevention of inequalities
Viding E, McCrory E. Individuals as active co-creators of their environments: implications for prevention of inequalities. Oxford Open Economics 2024, 3: i749-i753. DOI: 10.1093/ooec/odad071.Peer-Reviewed Original ResearchEarly adversityLatent vulnerabilityReduce inequalitiesGene-environment correlationAdaptability to adversityTargeted interventionsPattern of processingDispositional differencesPrevent inequalitiesEarly interventionContext of preventionInterventionIndividual dispositionsAdversityGenetic predispositionDevelopmental effectsCorrelational researchPreventionCo-creationActive co-creatorsIndividualsChildrenEducation domainInequalityLearning process
2022
Altered reward and effort processing in children with maltreatment experience: a potential indicator of mental health vulnerability
Armbruster-Genç D, Valton V, Neil L, Vuong V, Freeman Z, Packer K, Kiffin M, Roiser J, Viding E, McCrory E. Altered reward and effort processing in children with maltreatment experience: a potential indicator of mental health vulnerability. Neuropsychopharmacology 2022, 47: 1063-1070. PMID: 35149765, PMCID: PMC8832084, DOI: 10.1038/s41386-022-01284-7.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingInternalizing symptomsHistory of maltreatmentAnterior cingulate cortexEffort processingEffort-based decision-making taskDecision-making taskEffort-based decisionElevated internalizing symptomsNon-maltreated childrenImpact of maltreatmentMental health vulnerabilitiesFuture internalizing symptomsNeural indicesACC activationAltered rewardBehavioral indicesMaltreatment experiencesLatent vulnerabilityCingulate cortexEffort sensitivityGroup differencesRewardMaltreatmentLongitudinal study
2020
The case for a preventative approach to mental health: Childhood maltreatment, neuroimaging, and the theory of latent vulnerability
McCrory E. The case for a preventative approach to mental health: Childhood maltreatment, neuroimaging, and the theory of latent vulnerability. 2020, 175-189. DOI: 10.1093/med/9780198789697.003.0011.Peer-Reviewed Original ResearchPsychiatric disordersChildhood maltreatmentFuture psychiatric disordersMagnetic resonance imaging researchClinical studiesLatent vulnerabilityClinical approachFunctional magnetic resonance imaging (fMRI) researchEarly adverse environmentsAltered functioningMental healthDisordersPreventative approachMaltreatmentImaging research
2019
A review of childhood maltreatment, latent vulnerability and the brain: implications for clinical practice and prevention
Gerin M, Hanson E, Viding E, McCrory E. A review of childhood maltreatment, latent vulnerability and the brain: implications for clinical practice and prevention. Adoption & Fostering 2019, 43: 310-328. DOI: 10.1177/0308575919865356.Peer-Reviewed Original ResearchMental health problemsLatent vulnerabilityNeurocognitive alterationsChildhood maltreatmentFuture mental health problemsEarly adverse environmentsCommon mental health problemsEmotion regulationThreat processingExecutive controlNeurocognitive systemsHealth problemsPoor mental healthReward processingMaltreated childrenFunctional neuroimagingFuture psychopathologyChild maltreatmentMental healthMaltreatmentLong-term outcomesSuch experiencesFunctioningClinical implicationsChildrenNeurocognitive Adaptation and Mental Health Vulnerability Following Maltreatment: The Role of Social Functioning
McCrory E, Ogle J, Gerin M, Viding E. Neurocognitive Adaptation and Mental Health Vulnerability Following Maltreatment: The Role of Social Functioning. Child Maltreatment 2019, 24: 435-451. PMID: 30897955, DOI: 10.1177/1077559519830524.Peer-Reviewed Original ResearchConceptsSocial functioningEarly maltreatment experiencesMental health vulnerabilitiesMental health problemsNeurocognitive adaptationsEmotion regulationThreat processingStudy of childrenReward processingComputational psychiatryMental health disordersMaltreatment experiencesLatent vulnerabilityChildhood maltreatmentSocial supportFunctioningHealth disordersNeural functionMaltreatmentHealth vulnerabilityProcessingHealth problemsVulnerabilityKey findingsAdolescents
2017
A neurocomputational investigation of reinforcement-based decision making as a candidate latent vulnerability mechanism in maltreated children
Gerin M, Puetz V, Blair R, White S, Sethi A, Hoffmann F, Palmer A, Viding E, McCrory E. A neurocomputational investigation of reinforcement-based decision making as a candidate latent vulnerability mechanism in maltreated children. Development And Psychopathology 2017, 29: 1689-1705. PMID: 29162176, DOI: 10.1017/s095457941700133x.Peer-Reviewed Original ResearchConceptsMaltreated groupReinforcement-based decisionEarly adverse environmentsFunctional magnetic resonanceSuperior temporal gyrusMedial temporal structuresPassive avoidance taskMiddle cingulate gyrusNegative cuesReinforcement expectanciesMaltreated childrenPsychosocial functioningTemporal gyrusPrediction errorVulnerability mechanismsAvoidance taskNonmaltreated peersOrbitofrontal cortexLatent vulnerabilityChildhood abuseWidespread networkValue processingPsychiatric vulnerabilityValue representationCingulate gyrusAnnual Research Review: Childhood maltreatment, latent vulnerability and the shift to preventative psychiatry – the contribution of functional brain imaging
McCrory E, Gerin M, Viding E. Annual Research Review: Childhood maltreatment, latent vulnerability and the shift to preventative psychiatry – the contribution of functional brain imaging. Journal Of Child Psychology And Psychiatry 2017, 58: 338-357. PMID: 28295339, PMCID: PMC6849838, DOI: 10.1111/jcpp.12713.Peer-Reviewed Original ResearchConceptsAnterior cingulate cortexLatent vulnerabilityEmotion regulationThreat processingReward processingChildhood maltreatmentActive emotion regulationDorsal ACC activityReceipt of rewardAdverse caregiving environmentsFuture psychiatric disordersPsychiatric disordersFunctional brain imagingEffective preventative approachesEffortful processingExecutive controlStudy of childrenError monitoringPoor mental healthNeurocognitive domainsNeurocognitive functioningCaregiving environmentNeural responsesEarly neglectNeural responsiveness
2015
Exploring the Relationship Between Childhood Maltreatment and Addiction: A Review of the Neurocognitive Evidence
Puetz V, McCrory E. Exploring the Relationship Between Childhood Maltreatment and Addiction: A Review of the Neurocognitive Evidence. Current Addiction Reports 2015, 2: 318-325. PMID: 26550550, PMCID: PMC4628081, DOI: 10.1007/s40429-015-0073-8.Peer-Reviewed Original ResearchSubstance use disordersChildhood maltreatmentSeverity of illnessSevere clinical presentationClinical presentationPsychiatric disordersUse disordersBrain structuresHistory of maltreatmentDisordersAdultsRiskExecutive functioningMaltreatmentAlterationsNeurocognitive systemsSalient stimuliLatent vulnerabilityIllnessRisk environmentImpairmentThe theory of latent vulnerability: Reconceptualizing the link between childhood maltreatment and psychiatric disorder
McCrory E, Viding E. The theory of latent vulnerability: Reconceptualizing the link between childhood maltreatment and psychiatric disorder. Development And Psychopathology 2015, 27: 493-505. PMID: 25997767, DOI: 10.1017/s0954579415000115.Peer-Reviewed Original ResearchConceptsPsychiatric disordersMental health problemsLatent vulnerabilityPsychiatric riskHealth problemsClinical interventionsDisordersNeurocognitive domainsPrevention approachesChildhood maltreatmentIntervention opportunitiesRisk trajectoriesPsychiatry approachMemory processingInterventionThreat processingChildrenRiskVulnerable childrenMaltreatmentLong termLife spanRisk environmentMaltreating environment