2023
A systematic review of childhood maltreatment and resting state functional connectivity
Gerin M, Viding E, Herringa R, Russell J, McCrory E. A systematic review of childhood maltreatment and resting state functional connectivity. Developmental Cognitive Neuroscience 2023, 64: 101322. PMID: 37952287, PMCID: PMC10665826, DOI: 10.1016/j.dcn.2023.101322.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityAnterior cingulate cortexFunctional connectivityCingulate cortexChildhood maltreatmentAltered functional connectivityState functional connectivityDorsal anterior cingulate cortexNegative psychiatric outcomesVentral anterior cingulate cortexDorsolateral prefrontal cortexRsFC alterationsAltered connectivityInclusion criteriaAmygdala connectivityNineteen studiesPsychiatric outcomesFuture symptomsSystematic reviewBrain regionsClinical disordersBrain circuitsAnterior insulaPrefrontal cortexMaltreatment exposure
2020
Individual differences in sensitivity to the early environment as a function of amygdala and hippocampus volumes: An exploratory analysis in 12-year-old boys
Pluess M, De Brito S, Bartoli A, McCrory E, Viding E. Individual differences in sensitivity to the early environment as a function of amygdala and hippocampus volumes: An exploratory analysis in 12-year-old boys. Development And Psychopathology 2020, 34: 901-910. PMID: 33342453, DOI: 10.1017/s0954579420001698.Peer-Reviewed Original ResearchConceptsIndividual differencesLeft amygdalaEnvironmental influencesLeft amygdala volumeNeurobiological sensitivityImportant brain regionsChild behaviorBrain regionsEarly environmentContextual factorsPositive experiencesBrain structuresAmygdala volumePreliminary evidenceAmygdalaGeneral environmental qualityHippocampus volumeExploratory analysisBoysExploratory studyEnvironmental features
2015
Childhood Trauma and Neural Responses to Personalized Stress, Favorite-Food and Neutral-Relaxing Cues in Adolescents
Elsey J, Coates A, Lacadie CM, McCrory EJ, Sinha R, Mayes LC, Potenza MN. Childhood Trauma and Neural Responses to Personalized Stress, Favorite-Food and Neutral-Relaxing Cues in Adolescents. Neuropsychopharmacology 2015, 40: 1580-1589. PMID: 25567424, PMCID: PMC4915266, DOI: 10.1038/npp.2015.6.Peer-Reviewed Original ResearchConceptsChildhood traumaPersonalized stressSubjective anxietyFavorite-food cuesFunctional magnetic resonance imagingPhysical health outcomesCortico-limbic circuitryNeural correlatesMotivational stateTrauma exposureNeural responsesFunctional neuroimagingPrefrontal cortexStress cuesAnterior cingulateEmotional disturbanceCerebellar regionsCuesGroup differencesRisky behaviorsBrain regionsAdolescentsSubcortical structuresAnxietyIncreased activation
2011
Effects of DTNBP1 genotype on brain development in children
Tognin S, Viding E, McCrory E, Taylor L, O’Donovan M, McGuire P, Mechelli A. Effects of DTNBP1 genotype on brain development in children. Journal Of Child Psychology And Psychiatry 2011, 52: 1287-1294. PMID: 21639861, DOI: 10.1111/j.1469-7610.2011.02427.x.Peer-Reviewed Original ResearchConceptsBrain developmentBrain structuresWhite matter brain regionsLeft anterior cingulate gyrusAnterior cingulate gyrusWhite matter volumeLeft medial frontal areaLow-risk allelesVoxel-based morphometryHigh-risk allelesDystrobrevin-binding protein 1Magnetic resonance imagingInfluences brain developmentFamily-wise error correctionMedial frontal areasCingulate gyrusMatter volumeWhite matterWhole brainMale childrenPotential susceptibility geneResonance imagingBrain regionsSchizophrenia
2010
Effects of stressful life events on human brain structure: A longitudinal voxel-based morphometry study
Papagni S, Benetti S, Arulanantham S, McCrory E, McGuire P, Mechelli A. Effects of stressful life events on human brain structure: A longitudinal voxel-based morphometry study. Stress 2010, 14: 227-232. PMID: 21034297, DOI: 10.3109/10253890.2010.522279.Peer-Reviewed Original ResearchConceptsGray matter volumePost-traumatic stress disorderStressful life eventsNumber of SLEsPsychiatric diagnosisLongitudinal voxel-based morphometry studyVoxel-based morphometry studyGray matter changesFormal psychiatric diagnosisMagnetic resonance imagingRisk of illnessLife eventsMatter changesParahippocampal gyrusMatter volumeAnterior cingulateHealthy adultsMorphometry studyMental disordersResonance imagingBrain regionsBrain structuresStress disorderAnatomical scansTime pointsResearch Review: The neurobiology and genetics of maltreatment and adversity
McCrory E, De Brito SA, Viding E. Research Review: The neurobiology and genetics of maltreatment and adversity. Journal Of Child Psychology And Psychiatry 2010, 51: 1079-1095. PMID: 20546078, DOI: 10.1111/j.1469-7610.2010.02271.x.Peer-Reviewed Original ResearchConceptsChildhood maltreatmentEarly adversityFunctional brain differencesIndividual's genetic makeAdrenal axis stress responseAtypical developmentEmotional developmentNeurobiological developmentAtypical activationNeurobiological mechanismsBrain differencesPrefrontal cortexPsychiatric vulnerabilityEnvironmental experiencesAdversityEnvironmental adversityBrain regionsEarly stressMaltreatmentNeuroendocrine findingsChildrenAdultsCorpus callosumGenetic makeHuman studies