Hormone gene signature guides a novel therapeutic opportunity to improve sensitivity to HER family inhibition in lung cancer
Yochum Z, Stabile L. Hormone gene signature guides a novel therapeutic opportunity to improve sensitivity to HER family inhibition in lung cancer. Translational Lung Cancer Research 2020, 9: 1599-1605. PMID: 32953532, PMCID: PMC7481617, DOI: 10.21037/tlcr-20-617.Peer-Reviewed Original ResearchParadoxical functions of ZEB1 in EGFR -mutant lung cancer: tumor suppressor and driver of therapeutic resistance
Yochum Z, Socinski M, Burns T. Paradoxical functions of ZEB1 in EGFR -mutant lung cancer: tumor suppressor and driver of therapeutic resistance. Journal Of Thoracic Disease 2016, 8: e1528-e1531. PMID: 28066651, PMCID: PMC5179406, DOI: 10.21037/jtd.2016.11.59.Peer-Reviewed Original ResearchNon-small cell lung cancerLung cancerEGFR-mutant lung cancerCell lung cancerCancer-related deathAmplification/mutationEGFR mutationsALK translocationKRAS mutationsDistinct subtypesTherapeutic resistanceCancerMolecular driversPatientsTumor suppressorParadoxical functionsMutationsSubtypesSignificant advancesZEB1