2023
Atlas-scale single-cell multi-sample multi-condition data integration using scMerge2
Lin Y, Cao Y, Willie E, Patrick E, Yang J. Atlas-scale single-cell multi-sample multi-condition data integration using scMerge2. Nature Communications 2023, 14: 4272. PMID: 37460600, PMCID: PMC10352351, DOI: 10.1038/s41467-023-39923-2.Peer-Reviewed Original Research
2022
scJoint integrates atlas-scale single-cell RNA-seq and ATAC-seq data with transfer learning
Lin Y, Wu T, Wan S, Yang J, Wong W, Wang Y. scJoint integrates atlas-scale single-cell RNA-seq and ATAC-seq data with transfer learning. Nature Biotechnology 2022, 40: 703-710. PMID: 35058621, PMCID: PMC9186323, DOI: 10.1038/s41587-021-01161-6.Peer-Reviewed Original ResearchMeSH KeywordsChromatin Immunoprecipitation SequencingExome SequencingMachine LearningRNA-SeqSequence Analysis, RNASingle-Cell AnalysisConceptsData modalitiesTransfer learning methodDifferent data modalitiesSingle-cell multiomics dataTransfer learningUnlabeled dataMultimodal datasetLeverage informationNeural networkLearning methodsData compositionLabel transferLabel accuracyJoint visualizationHeterogeneous collectionPromising resultsUnprecedented paceVisualizationFrameworkMultiomics dataScRNA-seq dataDatasetNetworkScATAC-seq dataCell atlases