Timing of Calorie Restriction in Mice Impacts Host Metabolic Phenotype with Correlative Changes in Gut Microbiota
Zhang L, Xue X, Zhai R, Yang X, Li H, Zhao L, Zhang C. Timing of Calorie Restriction in Mice Impacts Host Metabolic Phenotype with Correlative Changes in Gut Microbiota. MSystems 2019, 4: 10.1128/msystems.00348-19. PMID: 31796564, PMCID: PMC6890928, DOI: 10.1128/msystems.00348-19.Peer-Reviewed Original ResearchGut microbiotaCalorie restrictionMetabolic phenotypeLate-night eatingRestricted calorie intakeSystemic inflammatory markersIntestinal barrier functionCalorie-restricted miceHost metabolic phenotypeEffects of CRRestriction of foodGut microbiota structureExtended fasting periodPhysiological changesInflammatory markersNormal chowFat accumulationFood intakeCalorie intakeCR miceGlucose metabolismMuscle lossOverall healthFasting periodMice