A randomized controlled trial for response of microbiome network to exercise and diet intervention in patients with nonalcoholic fatty liver disease
Cheng R, Wang L, Le S, Yang Y, Zhao C, Zhang X, Yang X, Xu T, Xu L, Wiklund P, Ge J, Lu D, Zhang C, Chen L, Cheng S. A randomized controlled trial for response of microbiome network to exercise and diet intervention in patients with nonalcoholic fatty liver disease. Nature Communications 2022, 13: 2555. PMID: 35538056, PMCID: PMC9091228, DOI: 10.1038/s41467-022-29968-0.Peer-Reviewed Original ResearchConceptsNonalcoholic fatty liver diseaseFatty liver diseaseDiet interventionPrimary outcomeLiver diseaseTreatment of NAFLDThird primary outcomeTRIAL REGISTRATION NUMBERLiver fat contentCombined aerobic exerciseEffects of interventionsLiver fatAerobic exerciseGlucose metabolismGut microbiotaRegistration numberLarger sample sizeMicrobiota compositionExploratory adPatientsAdverse effectsInterventionIntervention strategiesPrediabetesExercise