Label-Free Biosensor Imaging on Photonic Crystal Surfaces
Zhuo Y, Cunningham B. Label-Free Biosensor Imaging on Photonic Crystal Surfaces. Sensors 2015, 15: 21613-21635. PMID: 26343684, PMCID: PMC4610529, DOI: 10.3390/s150921613.Peer-Reviewed Original ResearchConceptsPhotonic crystal surfaceCrystal surfaceImaging detection instrumentMetal plasmonic nanoparticlesDielectric nanoparticlesPhotobleachable fluorescent dyesOptical scatteringDielectric permittivityNanostructure designSensing resolutionOperating principleSubstrate surfaceCytotoxic stainsOptical microscopyPlasmonic nanoparticlesBiomaterial interactionsMatrix surfaceBiomolecular layerDetection instrumentKinetic monitoringPhotonsLabel-freeNanoparticlesSurfaceNanoparticle contrast agentsRecent Advances in Biosensing With Photonic Crystal Surfaces: A Review
Cunningham B, Zhang M, Zhuo Y, Kwon L, Race C. Recent Advances in Biosensing With Photonic Crystal Surfaces: A Review. IEEE Sensors Journal 2015, 16: 3349-3366. PMID: 27642265, PMCID: PMC5021450, DOI: 10.1109/jsen.2015.2429738.Peer-Reviewed Original ResearchPhotonic crystal surfaceDetection of small moleculesCrystal surfaceAnalysis of drug-protein interactionsLabel-free high-resolution imagingDrug-protein interactionsDetection of disease biomarkersCancer biomarker detectionFluorescence enhancementLabel-free biosensingHigh-resolution imagesSmall moleculesOptical resonatorIndividual nanoparticlesBiomarker detectionPhotobleachable fluorescent dyesLife science researchDevice structureReview several recent advancesBiosensingDisease biomarkersHigh-resolution imaging of living cellsImaging of living cellsResolution imagesAnalysis of cells