2024
Characteristics of renal pathology and coagulation function in IgA nephropathy and IgA vasculitis associated nephritis
Wang Y, Wang H, Ma X, Zhu Z, Tian X, Fu R, Jia L. Characteristics of renal pathology and coagulation function in IgA nephropathy and IgA vasculitis associated nephritis. BMC Nephrology 2024, 25: 35. PMID: 38273279, PMCID: PMC10811929, DOI: 10.1186/s12882-024-03465-6.Peer-Reviewed Original ResearchConceptsIgAN patientsFibrinogen degradation productsIgA nephropathyIgAVN patientsLevels of plasma D-dimerLevels of serum creatininePartial remission rateSevere coagulation abnormalitiesPlasma D-dimerPoor renal functionChronic kidney injuryRemission ratePathological resultsSerum creatinineAbdominal symptomsRenal functionCoagulation abnormalitiesDeposition of fibrinogenKidney biopsyD-dimerKidney injuryCoagulation functionIgAVNIgAN groupMethodsA total
2023
VPA improves ferroptosis in tubular epithelial cells after cisplatin-induced acute kidney injury
Li Y, Li K, Zhao W, Wang H, Xue X, Chen X, Li W, Xu P, Wang K, Liu P, Tian X, Fu R. VPA improves ferroptosis in tubular epithelial cells after cisplatin-induced acute kidney injury. Frontiers In Pharmacology 2023, 14: 1147772. PMID: 37153759, PMCID: PMC10155836, DOI: 10.3389/fphar.2023.1147772.Peer-Reviewed Original ResearchCisplatin-induced acute kidney injuryAcute kidney injuryAcyl-CoA synthetase long-chain family member 4Valproic acidKidney injuryTubular epithelial cellsGlutathione peroxidase 4Renal injuryDownregulation of GPX4Cisplatin-induced AKI miceCisplatin-induced renal injuryFer-1 treatmentEpithelial cellsBlood urea nitrogenCell deathFamily member 4AKI miceSerum creatinineAntiepileptic drugsHistone deacetylase 1Protective effectUrea nitrogenViable treatmentTissue damageCisplatin treatment