2023
Colorectal Carcinoma With Sarcomatoid Components
Golconda U, McHugh K, Allende D, Collins K, Henn P, Lacambra M, Bejarano P, Groisman G, Loughrey M, Monappa V, Zhang X, Hornick J, Gonzalez R. Colorectal Carcinoma With Sarcomatoid Components. The American Journal Of Surgical Pathology 2023, 48: 465-474. PMID: 38155543, DOI: 10.1097/pas.0000000000002172.Peer-Reviewed Original ResearchConceptsSarcomatoid componentColorectal carcinomaUndifferentiated carcinomaTumor-infiltrating lymphocytesNodal metastasisAbdominal painDistant metastasisRare subtypeSMARCA4 lossTumor buddingHeterologous elementsRepair protein expressionRectosigmoid regionSpindle cellsGastrointestinal bleedingKeratin-positivePoor prognosisFollow-upCarcinomaMismatch repair protein expressionMolecular testingAdvanced stageTumorLoss of mismatch repair protein expressionProtein expression
2020
Splenic-vasculature involvement is associated with poor prognosis in resected distal pancreatic cancer
Yin F, Saad M, Lin J, Jackson CR, Ren B, Lawson C, Karamchandani DM, Bernabeu BQ, Jiang W, Dhir T, Zheng R, Schultz CW, Zhang D, Thomas CL, Zhang X, Lai J, Schild M, Zhang X, Xie H, Liu X. Splenic-vasculature involvement is associated with poor prognosis in resected distal pancreatic cancer. Gastroenterology Report 2020, 9: 139-145. PMID: 34026221, PMCID: PMC8128010, DOI: 10.1093/gastro/goaa084.Peer-Reviewed Original ResearchProgression-free survivalLarger tumor sizeOverall survivalStage pT3Radiographic evidencePrognostic valueTumor sizePancreatic cancerPancreatic carcinomaPredictors of PFSPost-operative adjuvant chemotherapyShorter progression-free survivalDistal pancreatic cancerSplenic artery invasionSplenic vein invasionIndependent risk factorPapillary mucinous neoplasmAdjuvant chemotherapyLymphovascular invasionNodal metastasisVein involvementDistant metastasisPerineural invasionPoor prognosisRetrospective study