2023
Colorectal Carcinoma With Sarcomatoid Components
Golconda U, McHugh K, Allende D, Collins K, Henn P, Lacambra M, Bejarano P, Groisman G, Loughrey M, Monappa V, Zhang X, Hornick J, Gonzalez R. Colorectal Carcinoma With Sarcomatoid Components. The American Journal Of Surgical Pathology 2023, 48: 465-474. PMID: 38155543, DOI: 10.1097/pas.0000000000002172.Peer-Reviewed Original ResearchConceptsSarcomatoid componentColorectal carcinomaUndifferentiated carcinomaTumor-infiltrating lymphocytesNodal metastasisAbdominal painDistant metastasisRare subtypeSMARCA4 lossTumor buddingHeterologous elementsRepair protein expressionRectosigmoid regionSpindle cellsGastrointestinal bleedingKeratin-positivePoor prognosisFollow-upCarcinomaMismatch repair protein expressionMolecular testingAdvanced stageTumorLoss of mismatch repair protein expressionProtein expression
2021
Clinicopathological significance of neutrophil-rich colorectal carcinoma
Rottmann BG, Patel N, Ahmed M, Deng Y, Ciarleglio M, Vyas M, Jain D, Zhang X. Clinicopathological significance of neutrophil-rich colorectal carcinoma. Journal Of Clinical Pathology 2021, 76: 34-39. PMID: 34312298, PMCID: PMC10910606, DOI: 10.1136/jclinpath-2021-207702.Peer-Reviewed Original ResearchConceptsRecurrence-free survivalColorectal carcinomaHistological gradeTumor locationRight-sided tumor locationTumor cellsDNA mismatch repair (MMR) statusIndependent risk factorKaplan-Meier analysisHigh histological gradeAdvanced TNM stageMismatch repair statusPrognostic significanceCRC casesClinicopathological significanceTNM stageMetastasis stagePatient prognosisRisk factorsClinicopathological parametersMultivariate analysisRepair statusPatientsCarcinomaHigh rate
2019
Glucose Metabolic Reprogramming and Cell Proliferation Arrest in Colorectal Micropapillary Carcinoma
Vyas M, Patel N, Celli R, Wajapeyee N, Jain D, Zhang X. Glucose Metabolic Reprogramming and Cell Proliferation Arrest in Colorectal Micropapillary Carcinoma. Gastroenterology Research 2019, 12: 128-134. PMID: 31236153, PMCID: PMC6575135, DOI: 10.14740/gr1145.Peer-Reviewed Original ResearchColorectal micropapillary carcinomaGlucose transporter 1Micropapillary carcinomaGlucose metabolic reprogrammingColorectal carcinomaGlandular componentMetabolic reprogrammingGlycogen metabolismFrequent lymphovascular invasionCancer cell growthMPC therapyLymphovascular invasionTumor cell survivalAggressive variantPoor outcomeCell cycle arrestColon cancer cellsKi-67Glycogen metabolizing enzymesMetabolizing enzymesCarcinomaTransporter 1Cell proliferation arrestHCT116 colon cancer cellsReal-time PCR analysis
2015
Interval colorectal carcinoma: An unsolved debate
Benedict M, Galvao Neto A, Zhang X. Interval colorectal carcinoma: An unsolved debate. World Journal Of Gastroenterology 2015, 21: 12735-12741. PMID: 26668498, PMCID: PMC4671029, DOI: 10.3748/wjg.v21.i45.12735.Peer-Reviewed Original ResearchConceptsInterval colorectal carcinomasColorectal carcinomaNegative screening testNew cancer diagnosesHigh-risk individualsPolypoid neoplasiasExcised lesionsGastrointestinal neoplasiaCommunity hospitalRisk individualsSignificant health riskScreening testMultifactorial natureCancer diagnosisNeoplasiaHealth risksUnsolved debatePatientsCarcinomaHospitalLesionsEndoscopistsDiseaseDiagnosis