2019
Parasite‐Derived Vesicular‐Mediated Protein Export by the Human Pathogen Babesia microti
Mamoun C, Thekkiniath J, Kilian N, Lawres L, Gewirtz M, Abraham A, Graham M, Liu X, Ledizet M. Parasite‐Derived Vesicular‐Mediated Protein Export by the Human Pathogen Babesia microti. The FASEB Journal 2019, 33: 649.2-649.2. DOI: 10.1096/fasebj.2019.33.1_supplement.649.2.Peer-Reviewed Original ResearchMajor morphogenetic changesImmunoelectron microscopy analysisB. microtiProtein exportPhylum ApicomplexaMorphogenetic changesSecreted proteinsCell fractionationIntraerythrocytic developmentCanonical motifsExport systemPlasma membraneErythrocyte cytoplasmMajor immunodominant antigenBabesia microtiParasitophorous vacuoleHost erythrocyteWorldwide geographic distributionMalaria-like illnessGeographic distributionMalaria parasitesCell environmentProteinFASEB JournalFull-text articles
2012
Nuclear localization of Klotho in brain: an anti-aging protein
German D, Khobahy I, Pastor J, Kuro-o M, Liu X. Nuclear localization of Klotho in brain: an anti-aging protein. Neurobiology Of Aging 2012, 33: 1483.e25-1483.e30. PMID: 22245317, PMCID: PMC3328593, DOI: 10.1016/j.neurobiolaging.2011.12.018.Peer-Reviewed Original ResearchConceptsExtracellular domainNuclear membraneSingle-pass transmembrane proteinMultiple fibroblast growth factor receptorsFibroblast growth factor receptorNuclear functionsPrecise cellular localizationTransmembrane proteinGrowth factor receptorNuclear localizationPlasma membraneTransmembrane formCellular localizationCell typesCultured cellsAnti-aging proteinCell membraneImmunoelectron microscopyLigand affinityWhole animalFactor receptorAntioxidant enzymesProteinKlotho proteinGenes
2001
Synaptotagmin VII as a Plasma Membrane Ca2+ Sensor in Exocytosis
Sugita S, Han W, Butz S, Liu X, Fernández-Chacón R, Lao Y, Südhof T. Synaptotagmin VII as a Plasma Membrane Ca2+ Sensor in Exocytosis. Neuron 2001, 30: 459-473. PMID: 11395007, DOI: 10.1016/s0896-6273(01)00290-2.Peer-Reviewed Original ResearchMeSH KeywordsAgingAlternative SplicingAmino Acid SequenceAnimalsAnimals, NewbornBrainCalciumCalcium-Binding ProteinsCell MembraneCloning, MolecularEmbryo, MammalianExocytosisExonsGene Expression Regulation, DevelopmentalGreen Fluorescent ProteinsLuminescent ProteinsMaleMembrane GlycoproteinsMiceMolecular Sequence DataNerve Tissue ProteinsOrgan SpecificityPC12 CellsRatsRecombinant Fusion ProteinsSequence AlignmentSequence Homology, Amino AcidSynapsesSynaptotagminsTransfectionConceptsSynaptotagmin VIIPlasma membraneNeuroendocrine PC12 cellsSynaptic vesiclesSynaptic vesicle exocytosisPlasma membrane Ca2Presynaptic active zoneVesicle exocytosisSynaptic exocytosisDependent exocytosisCentral synapsesRegulated patternSynaptotagmin IExocytosisMembrane Ca2SynaptotagminFusion partnerPC12 cellsNeuroendocrine cellsNeurotransmitter releasePotent inhibitorVesiclesActive zoneMembraneCells