2017
Bayesian Cox Proportional Hazards Model in Survival Analysis of HACE1 Gene with Age at Onset of Alzheimer's Disease
Wang KS, Liu Y, Gong S, Xu C, Xie X, Wang L, Luo X. Bayesian Cox Proportional Hazards Model in Survival Analysis of HACE1 Gene with Age at Onset of Alzheimer's Disease. International Journal Of Clinical Biostatistics And Biometrics 2017, 3 PMID: 29430571, PMCID: PMC5806706, DOI: 10.23937/2469-5831/1510014.Peer-Reviewed Original ResearchCox proportional hazards modelCox regression modelProportional hazards modelRisk of ADAAO of ADHACE1 geneAlzheimer's diseaseSurvival analysisHazards modelHazard ratioSingle nucleotide polymorphismsBayesian Cox proportional hazards modelMultiple logistic regression modelRegression modelsConfidence intervalsChronic neurodegenerative diseasesLogistic regression modelsAD patientsOnset (AAO) of ADG haplotypeNeurodegenerative disordersNeurodegenerative diseasesDiseaseStrong associationCommon form
2005
ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies
Luo X, Kranzler HR, Zuo L, Yang BZ, Lappalainen J, Gelernter J. ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies. Pharmacogenetics And Genomics 2005, 15: 755-768. PMID: 16220108, DOI: 10.1097/01.fpc.0000180141.77036.dc.Peer-Reviewed Original ResearchConceptsAlcohol dependenceDrug dependenceSingle nucleotide polymorphismsDiagnosis of alcoholLogistic regression analysisUnrelated healthy controlsUnrelated casesRigorous study designsGene variationRelative risk analysisHaplotype-based haplotype relative riskHealthy controlsRelative riskHaplotype relative risk analysisDisequilibrium testCase-control association analysisInitial studyStudy designTransmission disequilibrium testStrong associationHaplotype relative riskRegression analysisMarkersAffected offspringPresent study