Polymorphisms within ASTN2 gene are associated with age at onset of Alzheimer’s disease
Wang KS, Tonarelli S, Luo X, Wang L, Su B, Zuo L, Mao C, Rubin L, Briones D, Xu C. Polymorphisms within ASTN2 gene are associated with age at onset of Alzheimer’s disease. Journal Of Neural Transmission 2014, 122: 701-708. PMID: 25410587, DOI: 10.1007/s00702-014-1306-z.Peer-Reviewed Original ResearchConceptsAstrotactin 2AAO of ADASTN2 geneGenome-wide association analysisSingle nucleotide polymorphism panelFuture functional studiesGenetic architectureSignificant hitsAssociation analysisGenesFunctional studiesGenetic variantsAlzheimer's diseasePathogenesis of ADGenetic profileSNPsKaplan-Meier survival analysisGenetic factorsGenotypesAD interventionAD patientsNeurological conditionsAG genotypeCognitive disordersAA genotype