2023
Changes in Inflammatory Biomarkers in Patients with Schizophrenia: A 3-Year Retrospective Study
Zhu X, Li R, Zhu Y, Zhou J, Huang J, Zhou Y, Tong J, Zhang P, Luo X, Chen S, Li Y, Tian B, Tan S, Wang Z, Han X, Tian L, Li C, Tan Y. Changes in Inflammatory Biomarkers in Patients with Schizophrenia: A 3-Year Retrospective Study. Neuropsychiatric Disease And Treatment 2023, 19: 1597-1604. PMID: 37465565, PMCID: PMC10350427, DOI: 10.2147/ndt.s411028.Peer-Reviewed Original ResearchSystemic immune-inflammation indexMonocyte/lymphocyte ratioNeutrophil/lymphocyte ratioPlatelet/lymphocyte ratioLymphocyte ratioLYM countSex-matched healthy participantsComplete blood count dataContinuous antipsychotic treatmentPathophysiology of schizophreniaImmune system activationLinear mixed modelsBlood count dataImpact of ageInflammatory hypothesisInflammatory biomarkersNeutrophil countAntipsychotic treatmentInflammatory stateRetrospective studyHealthy controlsSystem activationPatientsFull courseSchizophrenia diagnosis
2022
Linear Mixed Model Analysis of Polygenic Hazard Score on Verbal Memory Decline in Alzheimer’s Disease
Wang K, Xu C, Theeke LA, Xiao D, Luo X, Xie C, Initiative A. Linear Mixed Model Analysis of Polygenic Hazard Score on Verbal Memory Decline in Alzheimer’s Disease. Nursing Research 2022, 72: 66-73. PMID: 36097266, DOI: 10.1097/nnr.0000000000000623.Peer-Reviewed Original ResearchConceptsRey Auditory Verbal Learning TestAuditory Verbal Learning TestMini-Mental State Examination scoreVerbal Learning TestVerbal memory declineState Examination scoreAPOE ε4 alleleVerbal memory lossDisease Neuroimaging InitiativeVerbal memoryCognitive measuresLearning TestLinear mixed modelsMemory declineMild cognitive impairmentExamination scoresLongitudinal effectsLinear mixed model analysisBaseline Mini-Mental State Examination scorePolygenic hazard scoreCognitive dysfunctionCognitive impairmentMixed model analysisAlzheimer's Disease Neuroimaging InitiativeAlzheimer's disease