Induced Regulatory T Cells Superimpose Their Suppressive Capacity with Effector T Cells in Lymph Nodes via Antigen-Specific S1p1-Dependent Egress Blockage
Geng S, Zhong Y, Zhou X, Zhao G, Xie X, Pei Y, Liu H, Zhang H, Shi Y, Wang B. Induced Regulatory T Cells Superimpose Their Suppressive Capacity with Effector T Cells in Lymph Nodes via Antigen-Specific S1p1-Dependent Egress Blockage. Frontiers In Immunology 2017, 8: 663. PMID: 28638384, PMCID: PMC5461288, DOI: 10.3389/fimmu.2017.00663.Peer-Reviewed Original ResearchEffector T cellsLymph nodesT cellsInduced Regulatory T CellsAntigen-specific mechanismsAntigen-specific TregsHilar lymph nodesRegulatory T cellsAirway inflammationSuppression targetsSuppressive capacityAntigen stimulationReceptor expressionPeripheral generationTherapeutic programSame receptorTregsOptimal inhibitionInflammationCellsAsthmaS1P1AllergensReceptors