2011
Endometrial stem cell transplantation restores dopamine production in a Parkinson’s disease model
Wolff EF, Gao X, Yao KV, Andrews ZB, Du H, Elsworth JD, Taylor HS. Endometrial stem cell transplantation restores dopamine production in a Parkinson’s disease model. Journal Of Cellular And Molecular Medicine 2011, 15: 747-755. PMID: 20406327, PMCID: PMC2998585, DOI: 10.1111/j.1582-4934.2010.01068.x.Peer-Reviewed Original ResearchConceptsParkinson's diseaseDopaminergic neuronsWhole-cell patch-clamp recordingsCell patch-clamp recordingsDopamine metabolite concentrationsPD mouse modelStem cell transplantationDisease modelsSite of lesionParkinson's disease modelPyramidal cell bodiesPatch-clamp recordingsMesenchymal stem-like cellsAllogenic stem cellsStem cellsStem-like cellsCell transplantationStriatal dopamineNeural markers nestinCentral neuronsDopaminergic cellsDendritic projectionsDopamine synthesisDopamine productionMouse model
2008
Human Endometrial Stem Cells Transplantation in a Parkinson's Disease Mouse Model.
Wolff E, Gao X, Andrews Z, Yao K, Du H, Taylor H. Human Endometrial Stem Cells Transplantation in a Parkinson's Disease Mouse Model. Biology Of Reproduction 2008, 78: 120-120. DOI: 10.1093/biolreprod/78.s1.120d.Peer-Reviewed Original ResearchDisease mouse modelParkinson's disease mouse modelTyrosine hydroxylaseNestin antibodyStriatal dopamineDopaminergic cellsDopaminergic pathwaysMouse modelMouse brainTherapeutic potentialNeurogenic differentiationWhole-cell patch-clamp recordingsCell patch-clamp recordingsPotassium channelsReproductive-aged womenStem cell transplantationBarium-sensitive potassium channelsDOPAC/dopamineDisease modelsNOD-SCID miceSensitive potassium channelsStem cellsParkinson's disease modelPyramidal cell bodiesPatch-clamp recordings