Pilot trial of KD018 with neo-adjuvant concurrent chemo-radiation therapy in patients with locally advanced rectal cancer.
Kann B, Johung K, Cheng Y, Lam W, Liu S, Decker R, Higgins S. Pilot trial of KD018 with neo-adjuvant concurrent chemo-radiation therapy in patients with locally advanced rectal cancer. Journal Of Clinical Oncology 2017, 35: e15162-e15162. DOI: 10.1200/jco.2017.35.15_suppl.e15162.Peer-Reviewed Original ResearchGI toxicityRectal cancerClinical studiesGrade 3Day 1Clinical stage T3-T4Concurrent chemo-radiation therapyPilot phase I trialPathologic partial responseStandardized pharmaceutical productsAdvanced rectal cancerPhase I trialStage T3-T4Favorable toxicity profileChemo-radiation therapyFirst clinical studyFirst clinical trialTraditional Chinese medicineAbdominal RTGI ailmentsN0-N2Po bidAccrual goalCTCAE v4.0Gastrointestinal toxicity