2020
Children and adolescents with type 1 and type 2 diabetes mellitus in the Pediatric Diabetes Consortium Registries: comparing clinical characteristics and glycaemic control
Van Name MA, Cheng P, Gal RL, Kollman C, Lynch J, Nelson B, Tamborlane WV, Consortium F. Children and adolescents with type 1 and type 2 diabetes mellitus in the Pediatric Diabetes Consortium Registries: comparing clinical characteristics and glycaemic control. Diabetic Medicine 2020, 37: 863-867. PMID: 31943374, DOI: 10.1111/dme.14233.Peer-Reviewed Original ResearchConceptsType 2 diabetesType 1 diabetesPediatric Diabetes ConsortiumTarget HbAType 1Median C-peptide levelsResidual endogenous insulin secretionType 2 diabetes mellitusC-peptide levelsEndogenous insulin secretionOverweight/obeseYears of agePoor diabetes outcomesSubset of participantsCharacteristics of childrenDiabetic ketoacidosisGlycaemic controlClinical characteristicsDiabetes mellitusDiabetes outcomesRisk factorsFamilies of childrenInsulin secretionInsulin treatmentDiabetes diagnosis
2015
Prevalence of cardiovascular risk factors in youth with type 1 diabetes and elevated body mass index
Redondo MJ, Foster NC, Libman IM, Mehta SN, Hathway JM, Bethin KE, Nathan BM, Ecker MA, Shah AC, DuBose SN, Tamborlane WV, Hoffman RP, Wong JC, Maahs DM, Beck RW, DiMeglio LA. Prevalence of cardiovascular risk factors in youth with type 1 diabetes and elevated body mass index. Acta Diabetologica 2015, 53: 271-277. PMID: 26077171, DOI: 10.1007/s00592-015-0785-1.Peer-Reviewed Original ResearchConceptsType 1 diabetesCardiovascular risk factorsHealthy weight participantsWeight participantsRisk factorsElevated body mass indexHealthy weight peersFrequency of hypertensionDiagnosis of hypertensionHealthy weight childrenBody mass indexYears of ageWarrants further investigationConclusionsObese childrenMass indexObese participantsT1D ExchangeWeight childrenMedical recordsPrevention criteriaWeight statusAimThe prevalenceHigh prevalenceChildren 2Dyslipidemia
2012
Body Mass Index at the Time of Diagnosis of Autoimmune Type 1 Diabetes in Children
Kaminski BM, Klingensmith GJ, Beck RW, Tamborlane WV, Lee J, Hassan K, Schatz D, Kollman C, Redondo MJ, Consortium P. Body Mass Index at the Time of Diagnosis of Autoimmune Type 1 Diabetes in Children. The Journal Of Pediatrics 2012, 162: 736-740.e1. PMID: 23092524, DOI: 10.1016/j.jpeds.2012.09.017.Peer-Reviewed Original ResearchConceptsAutoimmune type 1 diabetesType 1 diabetesGeneral populationDiabetic ketoacidosisT1D onsetHigher BMI z-scoreHispanic race/ethnicityDisease control populationsMedian BMI percentilePediatric Diabetes ConsortiumDiagnosis of T1DPediatric diabetes centersTime of diagnosisDays of diagnosisBody mass indexSame clinical characteristicsBody mass index distributionBMI z-scoreType 2 diabetesChildren ages 2Race/ethnicityClinical characteristicsDiabetes autoantibodiesDiabetes CenterLower hemoglobin
2007
Effects of a Weight Management Program on Body Composition and Metabolic Parameters in Overweight Children: A Randomized Controlled Trial
Savoye M, Shaw M, Dziura J, Tamborlane WV, Rose P, Guandalini C, Goldberg-Gell R, Burgert TS, Cali AM, Weiss R, Caprio S. Effects of a Weight Management Program on Body Composition and Metabolic Parameters in Overweight Children: A Randomized Controlled Trial. JAMA 2007, 297: 2697-2704. PMID: 17595270, DOI: 10.1001/jama.297.24.2697.Peer-Reviewed Original ResearchConceptsWeight management programWeight management groupOverweight childrenMetabolic complicationsInsulin resistanceBody fatBody compositionControl groupArray of comorbiditiesMost overweight childrenSix-month improvementsHomeostasis model assessmentPediatric obesity clinicSerious metabolic complicationWeight management counselingType 2 diabetesMajor health issueFamily-based programsMixed ethnic groupsMonths of studyHOMA-IRObesity clinicOverweight adultsControlled TrialsPediatric obesity
2005
Diabetes in overweight pediatric patients
Tamborlane WV. Diabetes in overweight pediatric patients. Clinical Cornerstone 2005, 7: s25-s29. PMID: 16545735, DOI: 10.1016/s1098-3597(05)80086-9.Peer-Reviewed Original ResearchConceptsDiabetes mellitusNew-onset type 2 diabetes mellitusType 2 diabetes mellitusChildhood diabetes mellitusOverweight pediatric patientsNew diabetes casesMore effective treatmentsPediatric patientsHemoglobin levelsInadequate therapyDiabetes casesDiabetic complicationsPatient satisfactionUrine testingFamily historyEffective treatmentDM treatmentBetter outcomesMetabolic controlInsulin analoguesType 2Ethnic minority groupsHigh rateDiseasePromising new avenue