2000
Impaired in vivo stimulation of lipolysis in adipose tissue by selective beta2-adrenergic agonist in obese adolescent girls.
Enoksson S, Talbot M, Rife F, Tamborlane WV, Sherwin RS, Caprio S. Impaired in vivo stimulation of lipolysis in adipose tissue by selective beta2-adrenergic agonist in obese adolescent girls. Diabetes 2000, 49: 2149-2153. PMID: 11118019, DOI: 10.2337/diabetes.49.12.2149.Peer-Reviewed Original ResearchConceptsSubcutaneous abdominal adipose tissueAbdominal adipose tissueBeta2-adrenergic agonistObese adolescent girlsGlycerol releaseAdipose tissueBMI 21Lean girlsObese womenObese girlsSelective beta2-adrenergic agonistAdolescent girlsSignificant differencesMobilization of fatBMI 36Lean womenAdrenergic systemLipolytic sensitivityAdolescent obesityLipolytic effectVivo stimulationBMI 38AgonistsWomenObesity
1995
Central adiposity and its metabolic correlates in obese adolescent girls
Caprio S, Hyman LD, Limb C, McCarthy S, Lange R, Sherwin RS, Shulman G, Tamborlane WV. Central adiposity and its metabolic correlates in obese adolescent girls. American Journal Of Physiology 1995, 269: e118-e126. PMID: 7631766, DOI: 10.1152/ajpendo.1995.269.1.e118.Peer-Reviewed Original ResearchConceptsObese adolescent girlsObese girlsInsulin secretionInsulin actionSubcutaneous abdominal fat depotsFree fatty acid levelsGlucose-stimulated insulin responseHip circumference ratioEuglycemic insulin clampHyperglycemic clamp techniqueBasal insulin secretionAbdominal fat depotsAdolescent girlsHepatic glucose productionFatty acid levelsMagnetic resonance imagingLean womenCentral adiposityInsulin dosesVisceral fatInsulin clampInsulin resistanceNonobese girlsGlucose disposalInsulin infusion