1995
Interstitial fluid concentrations of glycerol, glucose, and amino acids in human quadricep muscle and adipose tissue. Evidence for significant lipolysis in skeletal muscle.
Maggs DG, Jacob R, Rife F, Lange R, Leone P, During MJ, Tamborlane WV, Sherwin RS. Interstitial fluid concentrations of glycerol, glucose, and amino acids in human quadricep muscle and adipose tissue. Evidence for significant lipolysis in skeletal muscle. Journal Of Clinical Investigation 1995, 96: 370-377. PMID: 7615807, PMCID: PMC185209, DOI: 10.1172/jci118043.Peer-Reviewed Original ResearchConceptsAdipose tissueEuglycemic hyperinsulinemiaInterstitial glucoseSkeletal muscleInterstitial glycerol concentrationsInterstitial fluid concentrationsHuman skeletal muscleHuman quadriceps muscleInterstitial glycerolIntramuscular lipolysisReuptake blockadePlasma levelsPeripheral tissuesQuadriceps musclePlasma glycerolAlanine levelsFuel metabolismFluid concentrationsMuscleHyperinsulinemiaMetabolic fuelsHuman subjectsSimilar changesHigh rateTissue
1991
SUPPRESSION OF COUNTERREGULATORY HORMONE RESPONSE TO HYPOGLYCEMIA BY INSULIN PER SE
DIAMOND M, HALLARMAN L, STARICK-ZYCH K, JONES T, CONNOLLY-HOWARD M, TAMBORLANE W, SHERWIN R. SUPPRESSION OF COUNTERREGULATORY HORMONE RESPONSE TO HYPOGLYCEMIA BY INSULIN PER SE. The Journal Of Clinical Endocrinology & Metabolism 1991, 72: 1388-1390. PMID: 2026760, DOI: 10.1210/jcem-72-6-1388.Peer-Reviewed Original ResearchConceptsCounterregulatory hormone responsesHormone responseGlucose levelsNormal subjectsCounterregulatory hormone levelsResponses of epinephrineVariable glucose infusionDegree of hyperinsulinemiaHigh-dose studiesHypoglycemic clamp studiesHypoglycemic counterregulationHypoglycemic stimulusInsulin doseExogenous insulinDose studyHormone levelsGlucose infusionClamp studiesHypoglycemiaGrowth hormoneHypoglycemic plateauInsulinModulating effectOnly variableHyperinsulinemia