2011
Long-term Results of an Obesity Program in an Ethnically Diverse Pediatric Population
Savoye M, Nowicka P, Shaw M, Yu S, Dziura J, Chavent G, O'Malley G, Serrecchia JB, Tamborlane WV, Caprio S. Long-term Results of an Obesity Program in an Ethnically Diverse Pediatric Population. Pediatrics 2011, 127: 402-410. PMID: 21300674, PMCID: PMC3065145, DOI: 10.1542/peds.2010-0697.Peer-Reviewed Original ResearchConceptsControl groupLow-density lipoprotein cholesterolTotal body fat massIntensive lifestyle programIntensive lifestyle interventionHomeostasis model assessmentActive intervention phaseWeight management programBody fat massLong-term resultsBMI z-scorePercent body fatDiverse pediatric populationFamily-based programsLifestyle interventionLipoprotein cholesterolTotal cholesterolObese childrenObese populationPediatric populationInsulin resistanceObesity programLifestyle programFat massIntervention group
1996
Hyperleptinemia: an early sign of juvenile obesity. Relations to body fat depots and insulin concentrations
Caprio S, Tamborlane WV, Silver D, Robinson C, Leibel R, McCarthy S, Grozman A, Belous A, Maggs D, Sherwin RS. Hyperleptinemia: an early sign of juvenile obesity. Relations to body fat depots and insulin concentrations. American Journal Of Physiology 1996, 271: e626-e630. PMID: 8843759, DOI: 10.1152/ajpendo.1996.271.3.e626.Peer-Reviewed Original ResearchConceptsVisceral fat massLeptin levelsLeptin concentrationsFat depotsJuvenile obesityFat massInsulin concentrationsDb/db miceHyperglycemic clamp studiesAdult obese subjectsOb gene productDevelopment of obesityFa/fa ratsLeptin mRNA expressionSubcutaneous fat depotsMagnetic resonance imagingSpecific fat depotsObese subjectsNonobese subjectsObese childrenDb miceNonobese childrenAcute increaseObese stateHyperinsulinemic conditions