2000
Quantification of eNOS mRNA in the canine cardiac vasculature by competitive PCR
Fulton D, Papapetropoulos A, Zhang X, Catravas J, Hintze T, Sessa W. Quantification of eNOS mRNA in the canine cardiac vasculature by competitive PCR. AJP Heart And Circulatory Physiology 2000, 278: h658-h665. PMID: 10666099, DOI: 10.1152/ajpheart.2000.278.2.h658.Peer-Reviewed Original ResearchConceptsENOS mRNACoronary arteryCoronary microvesselsLeft ventricleENOS cDNAEndothelial nitric oxide synthase (eNOS) mRNANitric oxide synthase mRNAEndothelial cellsCanine aortic endothelial cellsRight coronary arteryENOS mRNA levelsEndothelial cell markersCompetitive PCRAortic endothelial cellsVon Willebrand factorVein endothelial cellsInducible NOSNeuronal NOSCanine vasculatureLarge arteriesCanine Left VentricleCell markersPathophysiological statesArteryCardiac vasculature
1996
Reduced Gene Expression of Vascular Endothelial NO Synthase and Cyclooxygenase-1 in Heart Failure
Smith C, Sun D, Hoegler C, Roth B, Zhang X, Zhao G, Xu X, Kobari Y, Pritchard K, Sessa W, Hintze T. Reduced Gene Expression of Vascular Endothelial NO Synthase and Cyclooxygenase-1 in Heart Failure. Circulation Research 1996, 78: 58-64. PMID: 8603506, DOI: 10.1161/01.res.78.1.58.Peer-Reviewed Original ResearchConceptsHeart failureCyclooxygenase-1Von Willebrand factorPacing-induced heart failureVentricular end-diastolic pressureEndothelial cellsEndothelium-dependent responsesEnd-diastolic pressureLeft ventricular pacingPeripheral blood vesselsDiastolic pressureVentricular pacingThoracic aortaClinical signsMongrel dogsWestern blottingBlood vesselsWillebrand factorArbitrary unitsEcNOSTotal RNADogsPresent studyFailureCells