1993
Effects of intrasphincteric botulinum toxin on the lower esophageal sphincter in piglets
Pasricha P, Ravich W, Kalloo A. Effects of intrasphincteric botulinum toxin on the lower esophageal sphincter in piglets. Gastroenterology 1993, 105: 1045-1049. PMID: 8405847, DOI: 10.1016/0016-5085(93)90947-b.Peer-Reviewed Original ResearchConceptsLES pressureLower esophageal sphincter pressureIntrasphincteric botulinum toxinEsophageal sphincter pressureLower esophageal sphincterRelease of acetylcholineGastrointestinal smooth muscleNormal saline injectionEvidence of toxicityBaseline lower esophageal sphincter pressureBoTx injectionNoncholinergic pathwaysAnticholinergic effectsSphincter pressureLES toneEsophageal sphincterGastrointestinal sphinctersBotulinum toxinNormal salineSaline injectionNerve terminalsParadoxical responseSmooth muscleBoTxSkeletal muscle
1990
Esophageal motility in an adult with a congenital H-type tracheoesophageal fistula
Heitmiller R, Nikoomanesh P, Ravich W. Esophageal motility in an adult with a congenital H-type tracheoesophageal fistula. Dysphagia 1990, 5: 138-141. PMID: 2249489, DOI: 10.1007/bf02412636.Peer-Reviewed Original ResearchConceptsCongenital H-type tracheoesophageal fistulaH-type tracheoesophageal fistulaTracheoesophageal fistulaRespiratory symptomsNormal lower esophageal sphincter pressureLower esophageal sphincter pressureLow-amplitude peristalsisCommon presenting complaintEsophageal motor abnormalitiesEsophageal sphincter pressureCongenital tracheoesophageal fistulaEsophageal symptomsSphincter pressureAdult patientsPresenting complaintEsophageal motilityMotor abnormalitiesFistula repairFistulaPatientsSymptomsFindings persistCase historiesAbnormalitiesPeristalsis