2021
Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8+ T-Cell Infiltration After Heart Transplantation
Bracamonte-Baran W, Gilotra N, Won T, Rodriguez K, Talor M, Oh B, Griffin J, Wittstein I, Sharma K, Skinner J, Johns R, Russell S, Anders R, Zhu Q, Halushka M, Brandacher G, Čiháková D. Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8+ T-Cell Infiltration After Heart Transplantation. Circulation Heart Failure 2021, 14: e007982. PMID: 34555935, PMCID: PMC8550427, DOI: 10.1161/circheartfailure.120.007982.Peer-Reviewed Original ResearchConceptsPD-L1 expressionT cell infiltrationPD-L1Heart transplantationEndothelial cellsHemodynamic parametersPD1/PD-L1 axisCD8 T-cell ratioMultivariate logistic regression analysisPeripheral blood mononuclear cellsMurine model resultsGraft endothelial cellsHeart transplant patientsPD-L1 axisT cell frequenciesT cell ratioHeart transplantation modelSurveillance endomyocardial biopsiesBlood mononuclear cellsHuman heart transplantationLogistic regression analysisGraft expressionLeukocyte compartmentLeukocyte patternModulates CD8
2020
Characteristics and Outcomes of Pulmonary Angioplasty With or Without Stenting for Sarcoidosis-Associated Pulmonary Hypertension: Systematic Review and Individual Participant Data Meta-Analysis
daSilva-deAbreu A, Bracamonte-Baran W, Condado J, Babaliaros V, Tafur-Soto J, Mandras S. Characteristics and Outcomes of Pulmonary Angioplasty With or Without Stenting for Sarcoidosis-Associated Pulmonary Hypertension: Systematic Review and Individual Participant Data Meta-Analysis. Current Problems In Cardiology 2020, 46: 100616. PMID: 32532452, DOI: 10.1016/j.cpcardiol.2020.100616.Peer-Reviewed Original ResearchMeSH KeywordsAngioplastyFemaleHumansHypertension, PulmonaryMaleMiddle AgedMulticenter Studies as TopicSarcoidosisStentsConceptsSarcoidosis-associated pulmonary hypertensionIndividual participant dataPulmonary angioplastyPulmonary hypertensionCase reportIndividual Participant Data Meta-AnalysisMulticenter registry studyNYHA FC IIIPulmonary vascular stenosisControlled Clinical TrialsSmall case seriesData Meta-AnalysisRegistry studyCase seriesFC IIIFocal stenosisDefinitive diagnosisClinical trialsPulmonary vesselsOutcome dataVascular stenosisStage IIIPatientsAngioplastySignificant improvement