Donor-derived exosomes
Morelli A, Bracamonte-Baran W, Burlingham W. Donor-derived exosomes. Current Opinion In Organ Transplantation 2017, 22: 46-54. PMID: 27898464, PMCID: PMC5407007, DOI: 10.1097/mot.0000000000000372.Peer-Reviewed Original ResearchConceptsDonor MHC moleculesAntigen-presenting cellsSemidirect pathwayLymphoid organsMHC moleculesT cellsPassenger leukocytesDendritic cellsRecipient antigen-presenting cellsDonor antigen-presenting cellsAcute rejection responseDraining lymphoid organsHost dendritic cellsT cell allosensitizationT cell effectorsT helper cellsT cell helpAlloreactive T helper cellsExtracellular vesiclesAcute rejectionAlloantigen exposureDonor exosomesHeart transplantationMaternal microchimerismMaternal antigens