2022
Expression and Potential Prognostic Value of SOX9, MCL-1 and SPOCK1 in Gastric Adenocarcinoma
Luo W, Nagaria T, Sun H, Ma J, Lombardo J, Bassett R, Cao A, Tan D. Expression and Potential Prognostic Value of SOX9, MCL-1 and SPOCK1 in Gastric Adenocarcinoma. Pathology & Oncology Research 2022, 28: 1610293. PMID: 35221802, PMCID: PMC8863590, DOI: 10.3389/pore.2022.1610293.Peer-Reviewed Original ResearchConceptsGastric cancerPrognostic valueGastric adenocarcinomaMcl-1Pathologic TNM stageDifferent treatment modalitiesCancer-related deathPotential prognostic valueFurther subgroup analysisNegative prognostic markerTumor heterogeneityDifferent molecular alterationsSOX9 expressionSPOCK1 expressionPrognostic roleCommon malignancyPoor prognosisTNM stageTreatment modalitiesSubgroup analysisPrognostic markerUnivariate analysisDisease prognosisDivergent differentiationMolecular alterations
2021
NUTM1-Rearranged Neoplasms—A Heterogeneous Group of Primitive Tumors with Expanding Spectrum of Histology and Molecular Alterations—An Updated Review
Luo W, Stevens T, Stafford P, Miettinen M, Gatalica Z, Vranic S. NUTM1-Rearranged Neoplasms—A Heterogeneous Group of Primitive Tumors with Expanding Spectrum of Histology and Molecular Alterations—An Updated Review. Current Oncology 2021, 28: 4485-4503. PMID: 34898574, PMCID: PMC8628659, DOI: 10.3390/curroncol28060381.Peer-Reviewed Original ResearchConceptsGenome-wide histone modificationsPost-meiotic spermatidsExpression of oncogenesTumor suppressor geneTranscription regulationHistone modificationsBromodomain proteinsNuclear proteinsRNA sequencingFusion proteinProtein productsSuppressor geneFusion partnerGenesSitu hybridizationDifferent clinical coursesProteinSkin adnexal tumorsPrimitive morphologyOncogenic driversInhibitor therapyClinical courseMolecular alterationsPrimitive tumorHematologic malignancies
2014
Mammary analog secretory carcinoma of salivary gland with high-grade histology arising in hard palate, report of a case and review of literature.
Luo W, Lindley S, Lindley P, Krempl G, Seethala R, Fung K. Mammary analog secretory carcinoma of salivary gland with high-grade histology arising in hard palate, report of a case and review of literature. International Journal Of Clinical And Experimental Pathology 2014, 7: 9008-22. PMID: 25674280, PMCID: PMC4313953.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkers, TumorBiopsyBreast NeoplasmsCarcinomaCranial IrradiationFemaleHumansImmunohistochemistryLymphatic MetastasisMagnetic Resonance ImagingNeoplasm GradingOncogene Proteins, FusionPalatal NeoplasmsPalate, HardRadiotherapy, AdjuvantRecombination, GeneticSalivary Gland NeoplasmsTomography, X-Ray ComputedTreatment OutcomeConceptsHigh-grade histologyMinor salivary glandsETV6-NTRK3 translocationSalivary gland tumorsParotid glandSalivary glandsGrade histologySecretory carcinomaHard palateOriginal tumorGland tumorsCervical lymph node metastasisMammary analogue secretory carcinomaPrimary salivary gland tumorsLow histologic gradeLymph node metastasisLow-grade malignancyAcinic cell carcinomaYears of ageHigh-grade transformationYear old adultsReview of literatureOverall prognosisBenign courseNode metastasis