2019
A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders
Rayner C, Coleman JRI, Purves KL, Hodsoll J, Goldsmith K, Alpers GW, Andersson E, Arolt V, Boberg J, Bögels S, Creswell C, Cooper P, Curtis C, Deckert J, Domschke K, El Alaoui S, Fehm L, Fydrich T, Gerlach AL, Grocholewski A, Hahlweg K, Hamm A, Hedman E, Heiervang ER, Hudson JL, Jöhren P, Keers R, Kircher T, Lang T, Lavebratt C, Lee SH, Lester KJ, Lindefors N, Margraf J, Nauta M, Pané-Farré CA, Pauli P, Rapee RM, Reif A, Rief W, Roberts S, Schalling M, Schneider S, Silverman WK, Ströhle A, Teismann T, Thastum M, Wannemüller A, Weber H, Wittchen HU, Wolf C, Rück C, Breen G, Eley TC. A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. Translational Psychiatry 2019, 9: 150. PMID: 31123309, PMCID: PMC6533285, DOI: 10.1038/s41398-019-0481-y.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyBehavioral therapyAnxiety disordersTherapy outcomeEvidence-based treatmentsPolygenic scoringMajor depressive disorderGenome-wide association studiesDepressive disorderGenome-wide associationStrong genetic correlationCommon genetic variantsComplex traitsSingle nucleotide polymorphismsWide associationStrongest predictorPsychopathologyAnxietyPersonalityGenetic overlapAssociation studiesGenetic correlationsGenetic variantsNucleotide polymorphismsDisorders
2012
Social Skills as a Mediator Between Anxiety Symptoms and Peer Interactions Among Children and Adolescents
Motoca LM, Williams S, Silverman WK. Social Skills as a Mediator Between Anxiety Symptoms and Peer Interactions Among Children and Adolescents. Journal Of Clinical Child & Adolescent Psychology 2012, 41: 329-336. PMID: 22471319, PMCID: PMC3348994, DOI: 10.1080/15374416.2012.668843.Peer-Reviewed Original ResearchConceptsYouth anxiety symptomsNegative peer interactionsSocial skillsParent ratingsAnxiety symptomsPeer interactionsYouth sexStructural equation modeling resultsPositive peer interactionsPrimary social phobiaAnxiety problemsSocial phobiaYouth ratingsSignificant moderatorCross-sectional designYouth ageSkillsYouthModeratorRatingsAdolescentsDepressive disorderChildrenPhobiaAnxiety
2010
An Examination of the Tripartite Model of Anxiety and Depression in an Outpatient Sample of Adolescents
Dia DA, Harrington D, Silverman WK. An Examination of the Tripartite Model of Anxiety and Depression in an Outpatient Sample of Adolescents. Journal Of Evidence-Based Social Work 2010, 7: 302-312. PMID: 20799129, DOI: 10.1080/19371910903178771.Peer-Reviewed Original ResearchConceptsTripartite modelCommon mental health problemsMental health problemsNegative affectivityCause of anxietyPhysiological hyperarousalSurvey packetAnxietyGeneral risk factorsOutpatient sampleTreatment programAdolescentsPrior researchRisk factorsDepressive disorderModification indicesAverage ageHealth problemsDepressionEffective preventionDistinct componentsClinical samplesHyperarousalAffectivityParticipants