Delayed surgery for localised and metastatic renal cell carcinoma: a systematic review and meta-analysis for the COVID-19 pandemic
Chan V, Tan W, Leow J, Tan W, Ong W, Chiu P, Gurung P, Pirola G, Orecchia L, Liew M, Lee H, Wang Y, Chen I, Castellani D, Wroclawski M, Mayor N, Sathianathen N, Braga I, Liu Z, Moon D, Tikkinen K, Kamat A, Meng M, Ficarra V, Giannarini G, Teoh J. Delayed surgery for localised and metastatic renal cell carcinoma: a systematic review and meta-analysis for the COVID-19 pandemic. World Journal Of Urology 2021, 39: 4295-4303. PMID: 34031748, PMCID: PMC8143063, DOI: 10.1007/s00345-021-03734-1.Peer-Reviewed Original ResearchConceptsMetastatic renal cell carcinomaRenal cell carcinomaLocalised RCCDelayed surgeryCytoreductive nephrectomyDeferred CNOverall survivalCell carcinomaTargeted therapyAssociated with worse cancer-specific survivalAssociated with better overall survivalT1a renal cell carcinomaEffect of delaying surgeryDeferred cytoreductive nephrectomyCancer-specific survivalMeta-analysisElective cancer surgeryNewcastle-Ottawa ScaleSystematic reviewComprehensive literature searchUpfront CNOncological effectivenessRisk of biasImmediate surgeryRandomised controlled trialsIs there still a role for digital rectal examination in the prostate cancer diagnostic pathway in the COVID-19 and post COVID-19 era?
Tan W, Wong A, Mahmalji W, Raza A. Is there still a role for digital rectal examination in the prostate cancer diagnostic pathway in the COVID-19 and post COVID-19 era? The Aging Male 2021, 24: 92-94. PMID: 34319201, DOI: 10.1080/13685538.2020.1786047.Peer-Reviewed Original ResearchConceptsDigital rectal examinationProstate cancer diagnostic pathwayProstate specific antigenSuspicion of prostate cancerCancer diagnostic pathwayDiagnostic pathwayProstate cancerRectal examinationClinical suspicion of prostate cancerAbnormal digital rectal examinationProstate specific antigen measurementsRaised prostate specific antigenReferral to secondary careClinical suspicionSpecific antigenClinical examinationClinical assessmentCOVID-19 eraCancerMRISecondary careCOVID-19ExaminationRadiology servicesCoronavirus-19