Wayne Fenton, PhD
Research Scientist in GeneticsDownloadHi-Res Photo
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About
Research
Overview
Medical Research Interests
Animals; Bacteria; Biological Phenomena; Cell Physiological Phenomena; Chemical Phenomena; Genetic Phenomena; Organisms; Phenomena and Processes
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Horwich lab
Research at a Glance
Yale Co-Authors
Frequent collaborators of Wayne Fenton's published research.
Arthur Horwich, MD
Publications
1997
Escherichia coli GroEL, structure, function
Weissman J, Fenton W, Braig K, Adams P, Horwich A. Escherichia coli GroEL, structure, function. 1997, 173-178. DOI: 10.1093/oso/9780198599494.003.0065.Peer-Reviewed Original Research
1988
Mitochondrial Import and Processing of Mutant Human Ornithine Transcarbamylase Precursors in Cultured Cells
Isaya G, Fenton W, Hendrick J, Furtak K, Kalousek F, Rosenberg L. Mitochondrial Import and Processing of Mutant Human Ornithine Transcarbamylase Precursors in Cultured Cells. Molecular And Cellular Biology 1988, 8: 5150-5158. DOI: 10.1128/mcb.8.12.5150-5158.1988.Peer-Reviewed Original ResearchConceptsLeader peptideMitochondrial importMutant precursorHeLa cellsAssociated with mitochondriaHuman ornithine transcarbamylaseAmino acid substitutionsOrnithine transcarbamylase precursorIntact HeLa cellsIntramitochondrial locationLack of bindingMutant proteinsMitochondrial matrixAcid substitutionsActive enzymeActive trimerMitochondrial fractionTrypsin protectionAffinity columnFractionation studiesMitochondriaCultured cellsCytosolOrnithine transcarbamylaseMutations