2020
A preliminary study on functional activation and connectivity during frustration in youths with bipolar disorder
Ross AJ, Roule AL, Deveney CM, Towbin KE, Brotman MA, Leibenluft E, Tseng W. A preliminary study on functional activation and connectivity during frustration in youths with bipolar disorder. Bipolar Disorders 2020, 23: 263-273. PMID: 32790927, PMCID: PMC8074834, DOI: 10.1111/bdi.12985.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAmygdalaBipolar DisorderFrustrationHumansMagnetic Resonance ImagingPrefrontal CortexConceptsInferior frontal gyrusFeedback processingBD youthNeural responsesReward-relevant stimuliFunctional activationSelf-reported frustrationSelf-reported affectAtypical activation patternsGoal-directed behaviorPrefrontal cortex connectivityBipolar disorderBipolar disorder youthAttentional abilitiesAttention taskImpaired attentionFMRI paradigmTask performanceFrontal gyrusAttention networkGreater recruitmentCortex connectivityGreater unhappinessIrritability symptomsInterest activation
2015
BEHAVIOR AND EMOTION MODULATION DEFICITS IN PRESCHOOLERS AT RISK FOR BIPOLAR DISORDER
Tseng W, Guyer AE, Briggs‐Gowan M, Axelson D, Birmaher B, Egger HL, Helm J, Stowe Z, Towbin KA, Wakschlag LS, Leibenluft E, Brotman MA. BEHAVIOR AND EMOTION MODULATION DEFICITS IN PRESCHOOLERS AT RISK FOR BIPOLAR DISORDER. Depression And Anxiety 2015, 32: 325-334. PMID: 25691090, PMCID: PMC4409452, DOI: 10.1002/da.22342.Peer-Reviewed Original ResearchConceptsBipolar disorderAppropriate clinical assessment toolFamilial riskLow-risk groupFirst-degree relativesClinical assessment toolHigh familial riskStandardized laboratory observationsOppositional defiant disorderFamily historyMood disordersModulation deficitsLower riskProdromal indicatorsPsychiatric assessmentChild Behavior ChecklistEarly interventionAnger modulationDefiant disorderDisordersLarge longitudinal sampleHigh-risk preschoolersBehavior ChecklistRiskEmotional problemsAn fMRI study of emotional face encoding in youth at risk for bipolar disorder
Tseng W, Bones BL, Kayser RR, Olsavsky AK, Fromm SJ, Pine DS, Leibenluft E, Brotman MA. An fMRI study of emotional face encoding in youth at risk for bipolar disorder. European Psychiatry 2015, 30: 94-98. PMID: 25172156, PMCID: PMC10656053, DOI: 10.1016/j.eurpsy.2014.05.004.Peer-Reviewed Original Research